Volume 22, Issue 1 (Iranian South Medical Journal 2019)
Iran South Med J 2019, 22(1): 54-61 |
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Farzaneh M, Hasanpour M, Daghbashi M, Mohammadi Baghmollaei E. A Case Report of a Novel Balanced Reciprocal Translocation t(2;14)(q11;q24) in a Young Woman with Two Pregnancy Losses. Iran South Med J 2019; 22 (1) :54-61
URL: http://ismj.bpums.ac.ir/article-1-1048-en.html
URL: http://ismj.bpums.ac.ir/article-1-1048-en.html
1- Department of Pathology, School of Medicine, Bushehr University of Medical Sciences, Bushehr, Iran
2- Department of Molecular Pathology and Cytogenetics, Mehr Laboratory, Boushehr, Iran
3- School of Medicine, Bushehr University of Medical Sciences, Bushehr, Iran
4- Department of Molecular Pathology and Cytogenetics, Mehr Laboratory, Boushehr, Iran , e.mohammadi_b@yahoo.com
2- Department of Molecular Pathology and Cytogenetics, Mehr Laboratory, Boushehr, Iran
3- School of Medicine, Bushehr University of Medical Sciences, Bushehr, Iran
4- Department of Molecular Pathology and Cytogenetics, Mehr Laboratory, Boushehr, Iran , e.mohammadi_b@yahoo.com
Abstract: (3685 Views)
Reciprocal chromosome translocations, especially balanced rearrangements are known to be one of the main causes of recurrent miscarriage. In this case report, we performed the clinical and cytogenetic analysis on a young couple with two pregnancy losses. Though the couple had a normal clinical study, the cytogenetic analysis revealed a balanced reciprocal translocation of t(2;14)(q11;q24) whereas the husband has a normal karyotype of 46,XY. Indeed based on the literature, this is the first report of t(2;14)(q11;q24) related to pregnancy loss. Therefore, cytogenetic tests are recommended for couples with a history of miscarriage more than twice.
Type of Study: Original |
Subject:
Gynecology
Received: 2018/04/21 | Accepted: 2018/11/12 | Published: 2019/04/7
Received: 2018/04/21 | Accepted: 2018/11/12 | Published: 2019/04/7
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