:: Volume 14, Issue 4 (Iranian South Medical Journal 2011) ::
Iran South Med J 2011, 14(4): 240-245 Back to browse issues page
Endocrine complications in patients with major β-thalassemia
Parastoo Rostami *1, Gisoo Hatami2, Afshin Shirkani2
1- school of Medicine, Bushehr University of Medical Sciencse, Bushehr, IRAN , drp_rostami@yahoo.com
2- school of Medicine, Bushehr University of Medical Sciencse, Bushehr, IRAN
Abstract:   (15170 Views)

Background: Endocrine complications in patients with major β –thalassemia related to iron overload that the most important cause of mortality and morbidity in this patients.This study evaluate prevalence of endocrine complications in major β -thalassemia. Methods: Sixty patients with major β- thalassemia enrolled in this study. Results: We assessed 60 patients, including 27 men and 33 female disorders with major β- thalassemia by age range (10-44 years-old). 26.8% of patients didn’t have any endocrine disorders, 23.5% of patients one disorder and 48.7% have more than two. The most common complications of endocrinewere: hypogonadism (66.7%), short stature (45%), hypoparathyroidism (21.7%), diabet mellitus (18.3%), impaired glucose tolerance (6.7%), overt hypothyroidism (1.65%), subclinical hypothyroidism (1.65%). Conclusion: High prevalence of endocrine complications found in this study may emphasize regular endocrine assessment. In thalassemic patients especially in patients over the age of 10 years old.

Keywords: βthalassemia major, hypoparathyroidism, short stature, hypogonadism, hypothyroidism, hypoparathyroidism
Full-Text [PDF 171 kb]   (2101 Downloads)    
Type of Study: Original | Subject: General
Received: 2010/08/6 | Accepted: 2011/02/11 | Published: 2011/11/30


XML   Persian Abstract   Print



Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 14, Issue 4 (Iranian South Medical Journal 2011) Back to browse issues page