Volume 9, Issue 1 (Iranian south medical of journals 2006)                   Iran South Med J 2006, 9(1): 36-44 | Back to browse issues page

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Hatami G, Motamed N, Darvishi Z. Outcomes and survival of neonates with Hypoxic Ischemic Encephalopathy (HIE) in a university hospital in Bushehr port 1999-2006 . Iran South Med J 2006; 9 (1) :36-44
URL: http://ismj.bpums.ac.ir/article-1-44-en.html
Outcomes and survival of neonates with Hypoxic Ischemic Encephalopathy (HIE) in a university hospital in Bushehr port 1999-2006
Gisoo Hatami * 1, Niloofar Motamed2 , Zeynab Darvishi
1- , gissoo_hat@yahoo.com
2- Medicine School
Abstract:   (27016 Views)
Background: Hypoxic Ischemic Encephalopathy (HIE) neonatorum is very important due to its high morbidity and mortality rates and long-term neuromotor outcomes. Methods: In order to evaluate outcomes in moderate to severe HIE, in a historical cohort study, medical records of all neonates with HIE during 1999-2006 in a university hospital were reviewed. Of 134 neonates who had been admitted, 94 cases could be evaluated and were in reach of follow-up. Results: A total of 77 deaths (81.9%) were found due to sequel of asphyxia. The survival rate was 17% with a median of 5 days. Of 17 alive neonates, 5 cases (29.4%) had cerebral palsy. The most important risk factors related to survival were: heart massage more than one minute, low first minute APGAR score, low PH in arterial blood gas analysis and low birth weight (P<0.05). Also emergency cesarean section was a major risk factor for death. Conclusion: HIE has high morbidity and mortality rates and needs urgent attention for implementation of prevention programs including more intensive intrapartum monitoring.
Keywords: Hypoxic Ischemic Encephalopathy, survival rate, neonate, Hypoxia
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Type of Study: Original | Subject: General
Received: 2005/12/15 | Accepted: 2006/07/24 | Published: 2009/01/14
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