:: Volume 17, Issue 1 (Iranian South Medical Journal 2014) ::
Iran South Med J 2014, 17(1): 42-48 Back to browse issues page
The survey of shigellosis frequency and determination of antibiotic resistance profile of isolated strains from infected children in Tehran
Shahla Abbaspour, Jalal Mardaneh 1, Khadijeh Ahmadi
1- , mardaneh@razi.tums.ac.ir
Abstract:   (4795 Views)

Background: Shigellosis is endemic throughout the world and it is among the most common causes of bacterial diarrheal diseases. Antibiotic resistance of Shigella is becoming a progressive problem in world. The aim of this study was the survey of shigellosis frequency and determination of antibiotic resistance profile of isolated strains from infected children in Tehran. Material and Methods: This study conducted on 9131 patients with acute diarrheal disease. For isolation of Shigella spp. from stool samples, culture performed on different selective and differential media. After confirmation of bacteria by biochemical tests, susceptibility testing was done by disc diffusion method according to clinical and laboratory standards (CLSI) recomendations. Results: Among 9131 stool samples, Shigella spp. was isolated from 90 cases. Shigella sonnei was the most common isolated species. 92/2 % of isolates were resistant to cotrimoxazole. In contrast, most of the Shigella spp. was founded to be sensitive to ciprofloxacin, imipenem and third-generation cephalosporins. Conclusion: Surveillance programs on antimicrobial resistance not only identify pathogenic bacterial species, by reporting data like serotyping, microorganisms incidence rates, and susceptibility to the antimicrobial agents currently used for treatment, but also contribute to monitoring the intervention strategies including removing organism from reservoirs.

Keywords: children, Shigellosis, antibiotic, resistance
Full-Text [PDF 262 kb]   (1472 Downloads)    
Type of Study: Original | Subject: General
Received: 2014/02/1 | Accepted: 2014/02/1 | Published: 2014/02/1


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Volume 17, Issue 1 (Iranian South Medical Journal 2014) Back to browse issues page