:: Volume 17, Issue 5 (Iranian South Medical Journal 2014) ::
Iran South Med J 2014, 17(5): 938-947 Back to browse issues page
Antimicrobial resistance pattern of Gram –negative bacilli isolated of Vali-Asr Hospital wards in Arak
Farshid Didgar1, Hussain Sarmadian 2, Reza Ghasemikhah3
1- Department. of infectious Disease. Arak university of medical sciences .Arak .IRAN
2- Department. of infectious Disease. Arak university of medical sciences .Arak .IRAN , dr.sarmadian@arakmu.ac.ir
3- Department. of parasitology and mycology. Arak university of medical sciences .Arak .IRAN
Abstract:   (4219 Views)

Background: Infectious diseases are of the most important causes of mortality all around the world particular in developing countries. Recently, the most important thing that has worried medical society is antibiotic resistance. Multi-resistant gram_negative rods are important pathogens in hospitals, causing high rate of mortality.The main goal of this study was to investigate the antimicrobial resistance patterns among common gram-negative bacilli isolated from patients of Vali-Asr Hospital. Material and Methods: This is a cross-sectional descriptive study conducted between the years 2010-2012 in Vali-Asr hospital in Arak. In this study 1120 specimen were examined. Bacterial strains were isolated by conventional methods from various clinical samples of patients including: blood, urine, wound, sputum, CSF, andetc.All isolates were examined for antimicrobial resistance using disc diffusion method. Results: In this study 737 specimen were positive cultures. A total of 332 isolates of Gram-negative bacilli were identified. The most frequent gram negative bacteria were isolated from urine, wound, blood, respiratory secretion and catheter. The most frequent pathogens were E.coli followed by k.pneumonia, entrobacter, p.oaeruginosa, Acinetobacter spp, citrobacter and proteus. High rate of resistance to third generation of cephalospoins & carbapenems observed amang isolates of Acintobacter spp.Prodution of extended spectrum beralactamases (ESBLS) was found in 51.4% of all Gram negative bacteria. Conclusion: Antibiotic resistance, particularly multi-drug resistance is frequent among microorganisms of ValiAsr Hospital. Resistance in our country, like other countries have been shown to be increased, so it is highly recommended to prohibit unnecessary prescription of antibiotics.

Keywords: Bacterial infection, Gram- Negative bacilli, Antimicrobial drugs, Antimicrobial resistance.
Full-Text [PDF 551 kb]   (1140 Downloads)    
Type of Study: Original | Subject: General
Received: 2014/10/15 | Accepted: 2014/10/15 | Published: 2014/10/15


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Volume 17, Issue 5 (Iranian South Medical Journal 2014) Back to browse issues page