:: Volume 17, Issue 6 (Iranian South Medical Journal 2015) ::
Iran South Med J 2015, 17(6): 1188-1194 Back to browse issues page
Correlation between metabolic syndrome and serum concentration of vitamin 25(OH)D
Afsaneh Talaei 1, Navidreza Mashayekhi2
1- Department of Endocrinology, Thyroid disorders research center, Arak university of medical scienceArak, IRAN , talaei@arakmu.ac.ir
2- Department of Cardiology, School of medicine, Arak university of medical science, Arak, IRAN
Abstract:   (4037 Views)

Background: The simultaneous occurrence of risk factors for both type II diabetes and coronary artery disease show the existence of "metabolic syndrome".The studies have been shown that vitamin D deficiency has an inverse correlation with the components of metabolic syndrome such as BMI,systolic blood pressure,waist,fatsing blood glucose,LDL cholesterol and insulin resistance. So, this sudy evaluated the association between metabolic syndrome and vitamin D deficiency.

Materials and Methods: In this cross – sectional study among overweight patients referred to private and public clinics,70 patients with metabolic syndrome based on ATPIII criteria and 70 overweight healthy participants were selected and mean of 25 hydroxyvitamin D level in the two groups were compared. Laboratory tests for lipid profile and fasting blood glucose and vitamin D level and also examinations for waist, weight,height were done. Mann-Whitney-U and Student-t-test were used to evaluate the relationship of vitamin D level and metabolic syndrome.

Results: Participants in this study were 63% female.The prevalence of vitamin D deficiency was 71.4% and 26.2% in metabolic and control groups, respectively (P 0.001). Mean of vitamin D was 20±22 and 27±17 ng / ml in metabolic and control groups respectively (P 0.01).

Conclusion: The findings showed a significant correlation between vitamin D deficiency and metabolic syndrome and vitamin D deficiency has a role in establishment of metabolic syndrome through different mechanisms.

Keywords: Diabetes, metabolic syndrome, deficiency, vitamin D
Full-Text [PDF 533 kb]   (1580 Downloads)    
Type of Study: Original | Subject: Biochemistry. Cell Biology and Genetics
Received: 2014/12/18 | Accepted: 2014/12/18 | Published: 2014/12/18


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Volume 17, Issue 6 (Iranian South Medical Journal 2015) Back to browse issues page