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:: Volume 20, Issue 5 (Iranian South Medical Journal 2017) ::
Iran South Med J 2017, 20(5): 492-500 Back to browse issues page
Levofloxacin Resistance in Blood and Urine Culture Samples in Khalij Fars Hospital of Bushehr
Fshemeh Hadavand 1, Katayon Vahdat *2, Sara Yazdani 3, Nilofar Motamed 4
1- The Persian Gulf Tropical Medicine Research Center, The Persian Gulf Biomedical Sciences Research Institute, Bushehr University of Medical Sciences, Bushehr, Iran
Department of Infectious Diseases, School of Medicine, Bushehr University of Medical Sciences, Bushehr, Iran
2- The Persian Gulf Tropical Medicine Research Center, The Persian Gulf Biomedical Sciences Research Institute, Bushehr University of Medical Sciences, Bushehr, Iran
Department of Infectious Diseases, School of Medicine, Bushehr University of Medical Sciences, Bushehr, Iran , k.vahdat@bpums.ac.ir
3- The Persian Gulf Tropical Medicine Research Center, The Persian Gulf Biomedical Sciences Research Institute, Bushehr University of Medical Sciences, Bushehr, Iran
4- Department of Community Medicine, School of Medicine, Bushehr University of Medical Sciences, Bushehr, Iran
The Persian Gulf Nuclear Medicine Research Center, The Persian Gulf Biomedical Sciences Research Institute, Bushehr University of Medical Sciences, Bushehr, Iran
Abstract:   (88 Views)
Background: Due to broad spectrum antimicrobial activity of Levofloxacin, it has been used widely around the world. Recently levofloxacin-resistance reports have been published. This study was done to evaluate resistance to levofloxacin in positive urine and blood cultures in Persian Gulf hospital in Bushehr, during 2015-16.
Materials and Methods: In  this cross- sectional study all positive urine and blood cultures were enrolled, if the amount of the isolated pathogen  colony counts were more than 105. Culture samples were divided into 3 groups including sensitive, intermediate and resistant; based on bacterial growth around discs. SPSS version 18.0 was used as the statistical analysis program, and a p-value of less than 0.05 was considered statistically significant.
Results: Cultures belonged to 150 patients including 61 (%40.7) male and 89 (%59.3) female subjects with mean age of 42.98 ± 29.25 years were studied. Culture samples were consisted of urine (% 50.7) and blood cultures (% 49.3). E.coli was the most common pathogen (% 46) and Klebsiella (% 16.7) was the second pathogen in all cultures. Regarding sensitivity to  levofloxacin, 119 (% 79.3) samples were sensitive, 22 (% 14.7) culture had intermediate sensitivity and 9 (%6) samples were resistant to levofloxacin. The only  resistant pathogen was E.coli.
Conclusion: This study showed that Levofloxacin has good activity
against many pathogens except for E.coli infections that showed some resistance. However , it can still be a good choice in treatment of most infections.
 
Keywords: Resistance, levofloxacin, blood culture, urine culture
Full-Text [PDF 652 kb]   (82 Downloads)    
Type of Study: Original | Subject: Microbiology and Immunology
Received: 2017/11/13 | Accepted: 2017/11/13 | Published: 2017/11/13
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Hadavand F, Vahdat K, Yazdani S, Motamed N. Levofloxacin Resistance in Blood and Urine Culture Samples in Khalij Fars Hospital of Bushehr. Iran South Med J. 2017; 20 (5) :492-500
URL: http://ismj.bpums.ac.ir/article-1-901-en.html
Volume 20, Issue 5 (Iranian South Medical Journal 2017) Back to browse issues page
دانشگاه علوم پزشکی بوشهر، طب جنوب ISMJ

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