Volume 21, Issue 5 (Iranian South Medical Journal 2018)                   Iran South Med J 2018, 21(5): 409-428 | Back to browse issues page

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Aleebrahim A, Nabipour I. Ethnopharmacology of Medicinal Plants in the Kangan- Asaluyeh Area. Iran South Med J 2018; 21 (5) :409-428
URL: http://ismj.bpums.ac.ir/article-1-960-en.html
1- The Persian Gulf Marine Biotechnology Research Center, The Persian Gulf Biomedical Sciences Research Institute, Bushehr University of Medical Sciences, Bushehr, Iran
Abstract:   (7534 Views)
Background: Ethnopharmacology, as a multidisciplinary approach for novel drug discovery, provides valuable data about medicinal plants in different cultures. The aim of this ethnopharmacological study was to identify medicinal plants in the Kangan-Asaluyeh area in the north of the Persian Gulf.
Material and Methods: The medical uses of medicinal plants were gathered from 20 local informants by face-to-face interviews. The relative frequency of citation (FRC) and cultural importance (CI) indices were calculated.
Results: A total of 90 medicinal plants belonging to 42 families were identified. Zataria multiflora, Teucrium polium, Salvia mirzayanii, Pistacia atlantica, Astragalus fasciculifolius, Achillea eriophora DC, Artemisia sieberi, Cassia italic and Haplophyllum tuberculatum had the highest CI and FRC indices. The highest medical uses were for gastrointestinal discomforts, infectious diseases, skin diseases, respiratory diseases, and the metabolic disorders, respectively.
Conclusion: There is a vast variety of medicinal plants in the Kangan-Asaluyeh area. Although most of the therapeutic applications of these plants in this region are the same as Iran’s traditional medicine, the people in the Kangan-Asalouyeh area use some of these plants for some diseases which are unique for this region. For example, the native people use Zataria multiflora, Teucrium polium, Pistacia atlantica, Artemisia sieberi for gastrointestinal discomfort and abdominal pain. They use Achillea eriophora DC, Haplophyllum tuberculatum for neonatal colic, Zataria multiflora for cough, Astragalus fasciculifolius for fracture, Teucrium polium and Artemisia sieberi for diabetes mellitus and inflammatory diseases, Cassia italic for constipation, Pistacia atlantica for diaper rash and sore throat, Haplophyllium tuberculatum for headache and improving mental health and Achillea eriophora DC for jaundice. Thus, investigation about these plants should be initiated to discover novel drugs for clinical applications.
Full-Text [PDF 891 kb]   (2955 Downloads)    
Type of Study: Original | Subject: Pharmacology
Received: 2018/05/4 | Accepted: 2018/07/16 | Published: 2018/11/3

References
1. Khamkar AD, Motghare VM, Deshpande R. Ethnopharmacology-A novel approach for drug discovery. Idia J Physiol Pharmacol 2015; 2(4): 222-5.
2. McGonigle IV. Patenting nature or protecting culture? Ethnopharmacology and indigenous intellectual property rights. J Leukoc Biol 2016; 3(1): 217-26.
3. Heinrich M. Ethnopharmacology in the 21st century-grand challenges. Front Pharmacol 2010; 1: 8.
4. Amin G. The Traditional Herbal Medicine in Iran. Tehran: Tehran University of Medical Sciences, Research Deputy of Health Ministry press, 2005 ,46. (Persian)
5. Mahboubi M. Management of Acute Cough by Zataria multiflora boiss as an alternative treatment. J Integr Med 2018; 16(1): 20-5.
6. Shayeganmehr A, Vasfi Marandi M, Karimi V, et al. Zataria multiflora essential oil reduces replication rate of avian influenza virus (H9N2 Subtype) in challenged broiler chicks. Br Poult Sci 2018; 59(4): 389-95.
7. Ariaee N, Ghorbani J, Panahi M, et al. Oral administration of Zataria multiflora extract decreases IL-17 expression in perennial allergic rhinitis. Rep Biochem Mol Biol 2018; 6(2): 203-7.
8. Kianmehr M, Haghmorad D, Nosratabadi R, et al. The effect of Zataria multiflora on Th1/Th2 and Th17/T regulatory in a mouse model of allergic asthma. Front Pharmacol 2017; 8: 458.
9. Alavinezhad A, Hedyati M, Boskaady MH. The effect Zataria multiflora and carcarvacrol on wheezing, FEV1, and plasma levels of nitric in asthmatic patients. Avicenna J Phytomed 2017; 7(6): 531-41.
10. Khazdair MR, Rajabi O, Balali-Mood M, et al. The effect of Zataria multiflora on pulmonary function tests, hematological and oxidant/ antioxidant parameters in sulfur mustard exposed veterans, A randomized doubled-blind clinical trial. Environ Toxicol Pharmacol 2018; 58: 180-8.
11. Meister A, Bernhardt G, Choristoffel V, et al. Antispasmodic activity of Thymus vulgaris extract on the isolated guinea-Pig trachea: discrimination between drug and ethanol effects. Planta Medica 1999; 65(6): 512-6.
12. Gharib Naseri MK, Mazlomi H, Goshaiesh M, et al. Antispasmodic effect of Zataria multiflora boiss. leaf extract on the rat uterus. Iran J Pharm Res 2010; 5(2): 131-6.
13. Reiter M, Brandt W. Relaxant effects on tracheal and ileal amooth muscles of the guinea Pig. Arzneimittelforschung 1985; 35(1A): 408-14.
14. Mahboubi M. Therapeutic potential of Zataria multiflora boiss in treatment of irritable bowel syndrome (IBS). J Diet Suppl 2018; 1-10.
15. Nakhai LA, Mohammadirad A, Yasa N, et al. Benefits of Zataria multiflora boiss in experimental model of mouse inflammatory bowel disease. eCAM 2007; 4(1): 43-50.
16. Moein S, Pimoradloo E, Moein M, et al. Evalution of antioxidant potentials and ∝ − amylase inhibition of different fractions of Labiatae plants extracts: As a model of antidiabetic compounds properties. Biomed Res Int 2017; 1-8.
17. Ghanbari-Niaki A, Saeidi A, Ahmadian M, et al. The combination of exercise training and Zataria multiflora supplementation increase serum irisin levels in postmenopausal women. IMR 2018; 7(1): 44-52.
18. Karimi F, Abbasi S, Bateni AR. The effect of Teucrium polium on blood glucose in diabetes mellitus type 2; A comparison with glibenclamide. Iran South Med J 2002; 2: 96-103.
19. Safaeian L, Ghanadian M, Shafiee-Moghadam Z, et al. Antihyperlipidemic effect of different fractions obtained from Teucrium polium hydroalcoholic extract in rats. International Am J Prev Med 2018; 9: 9-30.
20. Stefkov G, Kulevanova S, Miova B, et al. Effects of Teucrium polium spp. capitatum flavonoids on the lipid and carbohydrate metabolism in rats. Pharm Biol 2011; 49(9): 885-92.
21. Khodadadi S, Zabihi NA, Niazmand S, et al. Teucrium polium improves endothelial dysfunction by regulating eNOS and VCAM-1 genes expression and vasoreactivity in diabetic rat aorta. Biomed Pharmacother 2018; 103: 1526-30.
22. Gharib Naseri MK, Omidi Birgani F, Vakilzade G. Spasmolytic effect of Teucrium polium on virgin rat uterus. Iran J Basic Med Sci 2005; 8(1): 31-7.
23. Khadige A, Keshavarz Z, Mojab F, et al. The effect of Teucrium polium on the duration of menstrual bleeding: A Triple-blind placebo-controlled clinical trial. Electron Physician 2017; 9(9): 5233-6.
24. Alizadeh AM, Sohanaki H, Khaniki M, et al. The effect of Teucrium polium honey on the wound healing and tensile strength in rat. Iran J Basic Med Sci 2011; 14(6): 499-505.
25. Ziaei A, Amirghofran Z, Zapp J, et al. Immunoinhibitory effect of teuclatriol a guaiane sesquiterpene from salvia mirzayanii. Iran J Immunol 2011; 8(4): 226-35.
26. Sonboli A, Babakhani B, Mehrabian AR. Antimicrobial activity of six constituents of essential oil from Salvia. Zeitschrift für Naturforschung C 2006; 61(3-4): 160-4.
27. Mehrabani M, Heydari M, Mehrabani M. The effects of Solvia mirzayanii methanolic extract on acute and chronic antihyperglycemic in Rat. J Medicinal Plants 2010; 9(36): 106-16.
28. Ziaei A, Hoppstädter J, Kiemer AK, et al. Inhibitory effects of teuclatriol, A sesquiterpene from Salvia mirzayanii, on nuclear factor-κB activation and expression of inflammatory mediators. J Ethnopharmacol 2015; 160: 94-100.
29. Ziaei A, Ramezani M, Wright L, et al. Identification of spathulenol in Salvia mirzayanii and the immunomodulatory effects. Phytother Res 2011; 25(4): 557-62.
30. Ayatollahi AM, Ghanadian M, Att-ur-Rahman R, et al. Methoxylated flavones from Salvia mirzayanii rech. f. and esfand with immune suppressive properties. Iran J Pharm Res 2015; 14(3): 955-60.
31. Barzegar H, Hojjati M, Panahi M. Antioxidant and antimicrobial activity of different extracts of Pistacia atlantica leaf. Iran J Food Sci Technol 2017; 14(69): 147-58.
32. Memariani Z, Sharifzadeh M, Bozorgi M, et al. Protective effect of essential oil of Pistacia atlantica desf. on peptic ulcer: role of α-pinene. J Tradit Chin Med 2017;37(1): 57-63.
33. Haghdoost F, Baradarane Mahdavi M, Zandifar A, et al. Pistacia atlantica resin has a dose-dependent effect on angiogenesis and skin burn wound healing in rat. Evid Based Complement Alternat Med 2013; 2013: 893425.
34. Mehrabani M, Seyyedkazemi SM, Nematollahi MH, et al. Accelerated burn wound closure in mice with a new formula based on traditional medicine. Iran Red Crescent Med J 2016; 18(11): e26613.
35. Nikbakht MR, Soleimani Z, Moravveji SA, et al. Evaluating the effectiveness of Pistacia atlantica in the improvement of diabetic foot. Feyz 2016; 20(4): 347-51.
36. As’adi N, Kariman N, Mojab F, et al. The effect of saqez (Pistacia atlantica) ointment on the treatment of nipple fissure and nipple pain in breastfeeding women. Electronic physician 2017; 9(8): 4952-60.
37. Tanideh N, Davarmanesh M, Andisheh-tadbir A, et al. Healing acceleration atlantica (bene) essential oil in hamsters. J Oral Pathol Med 2017; 46(9): 725-30.
38. Ghahramani Dehbokri Sh, Saeidiani S, Mohammadzadeh R, et al. A comparative study of the healing effects of calendula and Astragalus fasciculifolius aqueous resin extract on rabbit skin wounds. J Vet Med 2010; 3(9): 51-61. (Persian)
39. Shirkani A, Mozaffari M, Zarei M. Antimicrobial effects of 14 medicinal plant speices of dashti in Bushehr province. Iran South Med J 2014;17(1): 49-57. (Persian)
40. Özbek H, Uğraş S, Dülger H, et al. Hepatoprotective effect of Foeniculum vulgare essential oil. Fitoterapia 2003; 74(3): 317-19.
41. Jaimand K, Rezaei M. Investigation on chemical constituents of essential oils from Achillea eriophora DC by distillation methods. Iran J Med Arom plant 2004; 20(1): 89-98.
42. Anvari S, Bahaoddini A, Moein M, et al. The effect of hydroalcoholic extract of Achillea eriophora DC. on blood pressure of anaesthetized male rat. Excli Journal 2016; 15: 797-806.
43. Arzi A, Akhavan M. The effect of hydroalcholic extract of Achillea millefolium on analgesic effect of morphine in rats. JBUMS 2001; 3(4): 11-4. (Persian)
44. Sedighi M, Naseri H, Rafieian-Kopaei M, et al. Reversal effect of Achillea millefolium extract on ileum contractions. J Herbmed Pharmacol 2013; 2(1): 5-8.
45. Dadkhah H, Fatemi F, Ababzadeh SH, et al. Potential preventive role of iranian Achillea wilhelmsii C. koch essetial oils in acetaminophen-Induced hepatotoaicity. Bot Stud 2014; 55(1): 37.
46. Morshedi A, Dashti RMH, Dehghan HM, et al. The effect of hydroolcholic extract of Artemisia sieberi on reducing neurogenic and inflammatory pain in mice 2011; 10(40):45-57.
47. Darabian A, Mosavi Z, Asgarpanah J, et al. In vivo Analgesic and anti-nflammatory effects of the essential oil from Artemisia sieberi fruit. RJP 2017; 4(4): 7-15.
48. Irshaid F, Mansi K, Bani-Khaled A, et al. Hepatoprotetive, cardioprotective and nephroprotective actions of essential oil Extract of Artemisia sieberi in Alloxan Induced Diabetic Rats. Iran J Pharm Res 2012; 11(4): 1227-34.
49. Khayoon HA, Ali AH, Kadhim TA, et al. Antidiabetic effect of Artemisia sieberi in rabbits that induced diabetic by alloxan. Health Perspect 2001; 109: 69.
50. Asgary S, Madani H, Mahzoni P, et al. Effect of Artemisia sieberi besser on plasma lipoproteins levels and progression of fatty streak in hypercholesterolemic rabbits. Iran J Med Aromat Plants 2006; 22(4): 303-14. (Persian)
51. Youssefi MR, Tabari MA, Moghadamnia AA. In vitro and in vivo activity of Artemisia sieberi against trichomonas gallinae. Iran J Vet Res 2017; 18(1): 25-9.
52. Hossaini M, Yousefi M, Abouhossaini Tbari M. Comparisan of the effect of Artemisia sieberi essential oil and albendazole dray on protosculeaes of hydatid cyst under in vitro conditions. Babol University Med Sci 2017; 19(12): 63-8. (persian)
53. Zargari A. Medicinal Plants. Vol 2. Tehran: university of Tehran Press, 1996, 105.
54. Parizan T, Elhamirad AH, Estiri SH, et al. Assessing antioxidant activity methanol extract of senna leaf and its effect on the stability of soybean oil. J Food Sci Technol 2011; 3(1): 51-9.
55. Ghazi Khanloo Sani K, Jafari MR, Khosravani A. Extract (Cassia angustifolia) on bowel preparation of patients undergoing diagnostic imaging of abdominal region. Hist Med 2011; 61-177.
56. Assane M, Nydyema R, Bassene E, et al. purgative activity of Cassia italica. Dakar Med 1994; 39(2): 125-8.
57. Lavari N, Ghasemi M, Nabipour I. Ethnopharmacology of Medicinal Plants in the Southwest of Mond Mountain. Iran South Med J 2017; 20(4): 380-98. (Persian)
58. Dastranj F, Karimi F, Rahmani N. Cytotoxic ealuations of metanolic extract fractions from Haplophyllum tuberculatum against RAJI and A594 cancerous cell lines. J Plant Res 2018; 31(1): 116-26.
59. Raissi A, Arbabi M, Roustakhiz J, et al. Haplophyllum tuberculatum: an overview. J herbMed pharmacol 2016; 5(4): 125-30.
60. Hamdi A, Majouli K, Abdelhamid A, et al. pharmacological activities of the organic extracts and fatty acid composition of the petroleum ether extract from Haplophyllum tuberculatum leaves. J Ethnopharmacol 2018; 216: 97-103.

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