RT - Journal Article T1 - Hypothesis Generation: Does Lu177 Therapy May be Effective for Treatment of Benign Prostate Hyperthrophy? JF - ISMJ YR - 2021 JO - ISMJ VO - 24 IS - 6 UR - http://ismj.bpums.ac.ir/article-1-1558-en.html SP - 637 EP - 638 K1 - benign prostate hypertrophy K1 - systemic radiation therapy K1 - lutetium AB - It has been decades full of documents to support the effectiveness and safety of I131 therapy for benign and malignant thyroid disease. Benign hyperfunctioning thyroid nodules and post thyroidectomy malignant metastases accumulate I131. Recently Lu177 PSMA has been successfully used for the treatment of prostate cancer metastases. Comparing the thyroid and prostate may bring a theory to treat benign prostate hypertrophy with Lu177 PSMA. Although proceeding to practice needs prior dosimetry study, effectiveness and safety evaluation, and cost-benefits assessment, the idea on its own is interesting. LA eng UL http://ismj.bpums.ac.ir/article-1-1558-en.html M3 10.52547/ismj.24.6.637 ER -