TY - JOUR T1 - The effect of clonidine as preanesthetic medication in children TT - تاثیر کلونیدین به عنوان پیش داروی قبل از بیهوشی بر وضعیت آرامبخشی و ریکاوری اطفال JF - ISMJ JO - ISMJ VL - 6 IS - 1 UR - http://ismj.bpums.ac.ir/article-1-106-en.html Y1 - 2003 SP - 31 EP - 36 KW - children KW - preanesthetic medication KW - clonidine KW - anxiety N2 - Separation of children from their parents at the time of transfer to operating room commonly cause severe anxiety which can induce undesired physiologic and psychologic Sequalea. For the purpose of sedation different pharmacologic and non pharmacological methods have been used. In the present study in order to achieve this object clonidine, an 2 agonist had been used because of its easy availability tastelessness and oral route of usage. 105 children aged 4-8 with ASA:I, candidate of elective operations were selected and randomly divided into three groups of 35 patients each the control, the clonidine-2 and the clonidine-4. 90 minutes before the expected time of transfer to operation room, 1ml/kg apple juice containing no drugs (control), clonidine 2g/kg (clonidine-2) or clonidine 4g/kg (clonidine-4) were given to the children. The state of sedation before premedication, at 30th, 60th and 90th minutes after premedicaiton, at the time of separation from the parents and anesthesia induction were evaluated. Also discharge readiness time were recorded. Comparison of sedation state showed that oral clonidine (in doses 2g/kg or 4g/kg) improved sedation and 90 minutes after usage only 12.5% of the control group patients, as compared with, 78.3% of the clonidine-2 and 90.5% of the clonidine-4 were drowsy (P M3 ER -