@ARTICLE{Tabib, author = {Tabib, Seyed masood and Mostaghni, Amir Ahmad and Valizadeh, Seyed Mohammad and }, title = {Assessment of endoscopic gastrostomy complications and the efficacy of single dose prophylactic antibiotic in 136 patients}, volume = {10}, number = {2}, abstract ={Background: Endoscopic gastrostomy provides a secure route for the provision of permanent enteral feeding. We performed this study to determine the incidence of endoscopic gastrostomy complications. Our secondary aim was to determine the efficacy of prophylactic antibiotic at the time of Percutaneous Endoscopic Gastrostomy (PEG) for reducing peristomal wound infection. Methods: The complications of endoscopic gastrostomy in 136 consecutive patients who had been referred to department of gastroenterology diseases of Fatemeh-Zahra hospital were recorded. Also in a randomized clinical trial the efficacy of a single dose of 1 g intravenous ceftriaxone or 5 g tetracycline cream 30 min before PEG insertion for prevention of gastrostomy wound infection was compared to those who received no prophylactic antibiotic. Results: A number of 77 male and 59 female patients were enrolled in this study. The mean age of the subjects was 49 ± 8 years. The most common indications for placement of the gastrostomy tube were cerebrovascular accident and brain trauma, respectively. Peristomal leakage was seen in 3.7% and gastrostomy wound infection after the first week, gastric ulceration and inadvertent PEG tube removal were detected each in 2.2% of subjects. Gastrostomy wound infection in the first 48 hours and one week follow-up after PEG insertion were not seen in the subjects. Conclusion: Percutaneous endoscopic gastrostomy is an easy, secure, and safe way to provide enteral feeding and the risk of major complications is negligible. The benefit of prophylactic antibiotics for prevention of gastrostomy wound infection is questionable. }, URL = {http://ismj.bpums.ac.ir/article-1-19-en.html}, eprint = {http://ismj.bpums.ac.ir/article-1-19-en.pdf}, journal = {Iranian South Medical Journal}, doi = {}, year = {2008} }