@ARTICLE{Tabib, author = {Tabib, Seyed Masoud and Ravanbod, Mohammadreza and Valizadeh, Seyed Mohammad and Farzaneh, Mohammadreza and }, title = {A case of Mantle Cell Lymphoma with Multiple Lymphomatous Polyposis }, volume = {13}, number = {4}, abstract ={Multiple Lymphomatous Polyposis (MLP) is characterized by multiple polyps involving long segments of the GI tract. More than 75% of the cases are derived from pregerminal center B cells (mantle zone B cells) & less than 25% from germinal center B cells. Thus MLP is a heterogenous group that includes Mantle Cell Lymphoma (MCL) & Follicular Lymphoma (FL). Here we present a 75-year-old sailor who referred to us with abdominal pain, bloody diarrhea, iron deficiency anemia & lymphadenopathy in inguinal & femoral regions. The presence of intestinal polyposis in colonoscopic & endoscopic evaluations & the pathologic & immunohistochemical findings on tissue specimens that showed B cell lymphoma with moderate proliferative activity (50%) & nodular proliferation of small lymphocytes accompanied with positivity for CD5, CD20, CD43 & negativity for CD3, CD10, CD23 revealed that these findings are consequent to MCL with accompanied MLP. }, URL = {http://ismj.bpums.ac.ir/article-1-235-en.html}, eprint = {http://ismj.bpums.ac.ir/article-1-235-en.pdf}, journal = {Iranian South Medical Journal}, doi = {}, year = {2010} }