AU - Soleimani, Solmaz AU - Yousefzadi, Morteza AU - Moein, Sohila AU - Amrollahi Bioki, Narges TI - Assessment of Anti- Inflammatory effect of sea urchin Echinometra mathaei From the Persian Gulf PT - JOURNAL ARTICLE TA - ISMJ JN - ISMJ VO - 18 VI - 6 IP - 6 4099 - http://ismj.bpums.ac.ir/article-1-754-en.html 4100 - http://ismj.bpums.ac.ir/article-1-754-en.pdf SO - ISMJ 6 ABĀ  - Background: sea urchins belonging to phylum echinoderms of marine invertebrates them found to possess excellent. Inflammation can be considered a set of complex processes that many body systems including the immune and nervous system are involved. The aim of the present research was undertaken to study the anti- inflammatory activity of different extracts, coelomic fluid and pigments shells and spines of sea urchin of Echinodermata mathaei. Material and method: Isolation of different tissues extracts (spine, shell, gonad and aristotol lantern) sea urchin by three solvents (n- hexan, ethyl acetate, methanol). Isolation coelomic fluid by buffered mode and pigments shell and spine by HCl of sea urchin evaluation antioxidant (DPPH radical scavenging) and anti- inflammatory activity investigated through inhibition albumin serum denaturation. Resuts: According to the results of the study, the spine- methanoli and coelomic fluid (CF) had the highest activity in the DPPH radical scavenging and aristotol lantern- ethyl acetate and pigment shell highest activity in the anti- inflammatory methods. Significant differences were observed at P<0.05. Conclusion: The result of this research indicated that sea urchin of E.mathaei due to the high antioxidant activity, have anti- inflammatory activities too. CP - IRAN IN - LG - eng PB - ISMJ PG - 1208 PT - Original YR - 2016