Volume 25, Issue 3 (Iranian South Medical Journal 2022)
Iran South Med J 2022, 25(3): 277-284 |
Back to browse issues page
Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
Mahmudpour M, Nabipour I, Esmailie A H, Amini A. A Case of Systemic Lupus Erythematosus with Renal Failure Following the Administration of Sinopharm COVID-19 Vaccine. Iran South Med J 2022; 25 (3) :277-284
URL: http://ismj.bpums.ac.ir/article-1-1631-en.html
URL: http://ismj.bpums.ac.ir/article-1-1631-en.html
1- The Persian Gulf Tropical Medicine Research Center, The Persian Gulf Biomedical Sciences Research Institute, Bushehr University of Medical Sciences, Bushehr, Iran
2- The Persian Gulf Marine Biotechnology Research Center, The Persian Gulf Biomedical Sciences Research Institute, Bushehr University of Medical Sciences, Bushehr, Iran
3- Department of Pathology, School of Medicine. Bushehr University Of Medical Sciences, Bushehr, Iran
4- Department of Internal Medicine, School of Medicine. Bushehr University Of Medical Sciences, Bushehr, Iran , amini_az@yahoo.com
2- The Persian Gulf Marine Biotechnology Research Center, The Persian Gulf Biomedical Sciences Research Institute, Bushehr University of Medical Sciences, Bushehr, Iran
3- Department of Pathology, School of Medicine. Bushehr University Of Medical Sciences, Bushehr, Iran
4- Department of Internal Medicine, School of Medicine. Bushehr University Of Medical Sciences, Bushehr, Iran , amini_az@yahoo.com
Abstract: (1380 Views)
The outbreak of COVID-19 has been revealed some pathogenic mechanisms which are indicating the role of virus in the pathogenesis of diseases such as diabetes mellitus, autoimmune and cardiovascular diseases. COVID-19 results in deterioration of glycemic control in diabetic patients and even in some cases developed new onset diabetes mellitus which are indicating the possible interfering role of SARS-CoV-2 in different metabolic pathways. Furthermore, during COVID-19 exacerbation of inactivated or de novo autoimmune diseases have been reported which indicate the causative role of virus in the stimulation of immune system and aggravation of autoimmune diseases through different mechanisms. In this report, a 31 year old male case of systemic lupus erythematosus (SLE) has been introduced who developed flu like illness, generalized edema and renal failure following the administration of third dose of Sinopharm BIBP COVID-19 (Sinopharm Beijing institute of Biological Products, China). During hospital course, proper therapeutic response was not achieved despite biopsy proven class IV lupus nephritis and standard therapy with methyl prednisolone and cyclophosphamide. He discharged with administration of routine hemodialysis thrice weekly. According to the course of disease, findings of biopsy and serologic tests, there were some challenging scenarios that are discussed in this report.
Type of Study: Case Report |
Subject:
Pathology
Received: 2022/05/29 | Accepted: 2022/07/5 | Published: 2022/09/22
Received: 2022/05/29 | Accepted: 2022/07/5 | Published: 2022/09/22
References
1. Iwata S, Tanaka Y. Association of viral infection with the development and pathogenesis of systemic lupus erythematosus. Front Med 2022; 9: 849120. [DOI]
2. Soliman NA. COVID-19 infection and the kidneys: Learning the lesson. J Infect Public Health 2021; 14(7): 922-926. [DOI]
3. Arantes MF, Rodrigues CE, Seabra VF, et al. Renal involvement in patients with COVID-19. Clin 2020; 75: e2194. [DOI]
4. Sethi S, D’Costa MR, Hermann SM, et al. Immune-Complex Glomerulonephritis After COVID-19 Infection. Kidney Int Rep 2021; 6(4): 1170–3. [DOI]
5. Klomjit N, Alexander MP, Fervenza FC, et al. COVID-19 Vaccination and Glomerulonephritis. Kidney Int Rep 2021; 6(12): 2969–2978. [DOI]
6. Appel GB, Jayne D. Lupus nephritis. In: Johnson R, Floege J, Feehaly J, eds. Comprehensive Clinical Nephrology. St. Louis: Elsevier; 2010. [Article]
7. Touzot M, Terrier CS, Faguer S, et al. Proliferative lupus nephritis in the absence of overt systemic lupus erythematosus: A historical study of 12 adult patients. Medicine (Baltimore) 2017; 96(48): e9017. [DOI]
8. Dooly MA, Hogan S, Jennette C, et al. Cyclophosphamide therapy for lupus nephritis: poor renal survival in black Americans. Glomerular Disease Collaborative Network. Kidney Int 1997; 51(4): 1188-95. [DOI]
9. Contreras G, Lenz O, Pardo V, et al. Outcomes in African Americans and Hispanics with lupus nephritis. Kidney Int 2006; 69(10): 1846-51. [PubMed]
10. Su H, Yang M, Wan C, et al. Renal histopathological analysis of 26 postmortem findings of patients with COVID-19 in China. Kidney Int 2020; 98(1): 219–227. [DOI]
11. Migliaccio MG, Di Mauro M, Ricciolino R, et al. Renal Involvement in COVID-19: A Review of the Literature. Infect Drug Resist 2021; 14: 895–903. [DOI]
12. Wang EY, Mao T, Klein J, et al. Diverse functional autoantibodies in patients with COVID-19. Nature 2021; 595(7866): 283-288. [DOI]
13. Liu Y, Ebinger JE, Mostafa R, et al. Paradoxical sex-specific patterns of autoantibody response to SARS-CoV-2 infection. J Transl Med 2021; 19: 524. [Article]
14. Sacchi MC, Tamiazzo S, Stobbione P, et al. SARS-CoV-2 infection as a trigger of autoimmune response. Clin Transl Sci 2021; 14(3): 898-907. [DOI]
15. Chang SE, Feng A, Meng W, et al. New-onset IgG autoantibodies in hospitalized patients with COVID-19. Nat Commun 2021; 12(1): 5417. [DOI]
16. Zhang Y, Xiao M, Zhang S, et al. Coagulopathy and Antiphospholipid Antibodies in Patients with Covid-19. N Engl J Med 2020; 382(17): e38. [DOI]
17. Zuo Y, Estes SK, Ali RA, et al. Prothrombotic autoantibodies in serum from patients hospitalized with COVID-19. Sci Transl Med 2020; 12(570): eabd3876. [DOI]
18. Haas M, Kaul S, Eustace JA. HIV-associated immune complex glomerulonephritis with “ lupus-like” features: A clinicopathologic study of 14 cases. Kidney Int 2005; 67(4): 1381–90. [DOI]
19. Roy S, Gupta R, Adapa S, et al. Hepatitis B-Associated Lupus-Like Glomerulonephritis Successfully Treated With Antiretroviral Drugs and Prednisone: A Case Report and Literature Review. J Investig Med High Impact Case Rep 2022; 10: 23247096221086451. [DOI]
20. Hobeika L, Srivastava M, Vo M, et al. Lupus-like glomerulonephritis: an autoimmune complication of hepatitis C infection. CEN Case Rep 2012; 1(1): 29–33. [DOI]
Send email to the article author
| Rights and Permissions | |
 |
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |
