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:: Volume 8, Issue 1 (Iranian south medical of journals 2005) ::
Iran South Med J 2005, 8(1): 37-42 Back to browse issues page
Evaluating autoimmunity markers (TPO Ab, Tg Ab and TM Ab) in hypothyroid patients of Bushehr province
Iraj Nabipour Mr 1, Fatemeh Rezapour Ms2, Seyed Mojtaba Jafary Mr
1- , nabipour@bpums.ac.ir
2- Medicine School
Abstract:   (17508 Views)
Background: Chronic autoimmune thyroiditis (Hashimoto's Thyroiditis) is the common cause of primary hypothyroidism in iodine sufficient countries. Iran is named an iodine sufficient country, in this century. Methods: A total of 88 hypothyroid patients, on suppressing dose of levothyroxine who were followed in a university endocrine disorder clinic were evaluated for serum thyroid autoimmunity markers: thyroid peroxidase antibody (TPO Ab), thyroglobulin antibody (Tg Ab) and thyroid microsomal antibody (TM Ab) using ELISA method. Results: The prevalence of TPO Ab, Tg Ab and TM Ab were 73.9%, 45.5% and 71.6%, respectively. Among the patients with high level of TPO Ab (> 75 u/ml), 45.3% had grade 1 or 2 of goiter (P< 0.05). Conclusion: Autoimmune thyroid disease (Hashimoto's thyroiditis) is the most common cause of hypothyroidism in Bushehr province.
Keywords: hypothyroidism; autoimmune thyroiditis; TPO Ab; Tg Ab; TM Ab
Full-Text [PDF 138 kb]   (1545 Downloads)    
Type of Study: Original | Subject: General
Received: 2005/06/10 | Accepted: 2005/08/6 | Published: 2009/01/14
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Nabipour I, Rezapour F, Jafary S M. Evaluating autoimmunity markers (TPO Ab, Tg Ab and TM Ab) in hypothyroid patients of Bushehr province . Iran South Med J. 2005; 8 (1) :37-42
URL: http://ismj.bpums.ac.ir/article-1-57-en.html


Volume 8, Issue 1 (Iranian south medical of journals 2005) Back to browse issues page
دانشگاه علوم پزشکی بوشهر، طب جنوب ISMJ

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