TY - JOUR T1 - A Case Report of a Novel Balanced Reciprocal Translocation t(2;14)(q11;q24) in a Young Woman with Two Pregnancy Losses TT - گزارش یک مورد جابجایی دو طرفه متعادل t(2;14)(q11;q24) در زن جوانی با 2 بار سابقه سقط JF - ISMJ JO - ISMJ VL - 22 IS - 1 UR - http://ismj.bpums.ac.ir/article-1-1048-en.html Y1 - 2019 SP - 54 EP - 61 KW - Recurrent miscarriage KW - Balanced translocation KW - t(2 KW - 14) N2 - Reciprocal chromosome translocations, especially balanced rearrangements are known to be one of the main causes of recurrent miscarriage. In this case report, we performed the clinical and cytogenetic analysis on a young couple with two pregnancy losses. Though the couple had a normal clinical study, the cytogenetic analysis revealed a balanced reciprocal translocation of t(2;14)(q11;q24) whereas the husband has a normal karyotype of 46,XY. Indeed based on the literature, this is the first report of t(2;14)(q11;q24) related to pregnancy loss. Therefore, cytogenetic tests are recommended for couples with a history of miscarriage more than twice. M3 10.29252/ismj.22.1.54 ER -