@article{ author = {Nazifi, Saeed and Saeb, Medhi and PorGonabadi, Soolmaz and Saeb, Saeedeh and AnsariLari, Maryam}, title = {The Effect of Dietary Wild Pistachio Oil (Pistacia atlantica) on Serum Thyroid Hormones and Leptin Concentration in Experimental Hyperthyroidism in the Female Rat}, abstract ={Background: Unsaturated fatty acids such as turpentine oil can decrease serum leptin level with attention to this effect and the axial role of thyroid hormones and leptin in metabolism, the aim of the present study was to investigate the impact of dietary wild pistachio oil on serum leptin concentration and its relationship with thyroid hormones in experimental hyperthyroidism in Sprague Dawely female rat. Methods: 30 healthy adult female rats was selected and divided into five groups. Animals were fed with normal diet, levothyroxine plus normal diet, and 5, 10, 20 percent of turpentine oil plus normal diet respectively. Duration of the study was one month sampling obtained in each ten day intervals. Hyperthyroidism was created in animals with dosage of 12 mg/l of levothyroxine in drinking water for one month. Rats treated with 5%, 10% and 20% concentrations of wild pistachio oil for one month. Blood samples were collected from heart in each ten days interval. Results: No difference was observed in thyroid hormones and leptin in control group (P>0.05). With an increasing in turpentine oil in diet a significant reduction was obtained for T4, T3 and fT4 respectively (P<0.05). A significant decrease also was observed with increase of 10 and 20 percent of turpentine oil in serum leptin level as compared to control group (P<0.05). There is a clear relationship between percent of turpentine oil feeding and thyroid and leptin hormone levels in experimental hyperthyroidism rats (P<0.05). Wild pistachio oil had been positive impression on reducing hyperthyroidism effects especially T4 concentration (P<0.05). Wild pistachio oil usage in the hyperthyroidismic rats caused to decrease significantly the serum concentration of leptin during the experimental period (P<0.05). Conclusion: There is a clear relationship between percent of turpentine oil feeding and thyroid and leptin hormone levels in experimental hyperthyroidism rats. Therefore, this study indicates that consumption of turpentine oil could induce the renovation of hyperthyroidism from regulation of leptin secretion and metabolism.}, Keywords = {wild pistachio oil, leptin, hyperthyroidism, thyroid hormones, female rat}, volume = {14}, Number = {1}, pages = {1-8}, publisher = {Bushehr University of Medical Sciences}, url = {http://ismj.bpums.ac.ir/article-1-238-en.html}, eprint = {http://ismj.bpums.ac.ir/article-1-238-en.pdf}, journal = {Iranian South Medical Journal}, issn = {1735-4374}, eissn = {1735-6954}, year = {2011} } @article{ author = {Kazemi, Masoomeh and Sahraie, Hedayat}, title = {The Effect of Oral Morphine Consumption on Ependymal Duct and Spinal Cord Development in Wistar Rats Embryos}, abstract ={Background: Previous studies have shown that morphine consumption during pregnancy may delay embryo development or cause abnormal nervous system function. The present study focused on the effects of maternal morphine consumption on ependyma duct and spinal cord development in Wistar rats. Methods: Wistar rats (170-200g) were used throughout. The experimental groups after fertility received 0.05 mg/ml of morphine by tap water while, the control group received water. On 17th day of pregnancy, the pregnant animals were anesthetized by chloroform and the embryos were removed surgically. The embryos were fixed in formalin 10% for 4 weeks. Then, tissue processing, sectioning and staining hematoxylin and eosin (H;E), were applied for the embryos. The sections were examined for ependyma duct and spinal cord development by light microscope and MOTIC ,SPSS software. Results: Severe reduction of the area ependyma duct and an increase in the marginal layer of spinal cord area were observed in the experimental group. In addition, an increase in the mantle layer area and number cells of spinal cord in the experimental group regarding to controls was identified. Conclusion: The study showed that oral morphine consumption has caused to a decrease ependyma duct and spinal cord .This defect may cause postponed on function and development central neuron system. such as, changes observed in the fetus born by opioid addicted women.}, Keywords = {morphine, teratogenicity , embryo, wistar rats, development , ependymal duct, spinal cord}, volume = {14}, Number = {1}, pages = {9-16}, publisher = {Bushehr University of Medical Sciences}, url = {http://ismj.bpums.ac.ir/article-1-239-en.html}, eprint = {http://ismj.bpums.ac.ir/article-1-239-en.pdf}, journal = {Iranian South Medical Journal}, issn = {1735-4374}, eissn = {1735-6954}, year = {2011} } @article{ author = {Derakhshesh, behrouz and Yousefzadi, Morteza and Afsharnasab, Mohammad and Yeganeh, Vahid and DashtianNasab, Aghil}, title = {In vitro Antibacterial Activities of the Marine Macroalgae" Laurencia Snyderiae" and "Sargassum Angustifolium" Against Human Pathogens}, abstract ={Background: Nowadays widespread applications of antibiotics caused to create resistant microorganisms and increased additive antibiotic resistance in all over the world. Thus, researches linked to investigate new antimicrobial agents that are produced in natural way have great significance to achieve new pharmaceutics resources. Based on many accomplished researches, some macroalgae have found to show noticeable antimicrobial and antifungal activities. Methods: In this research antimicrobial activity of organic extracts of the macroalgae "Laurencia snyderiae" and Sargassum angustifolium (which has been collected from coasts of Boushehr port) was tested against 3 Gram- positive bacteria Streptococous mutans, Streptococous salivaris and Streptococous sanguis as well as 4 Gram- negative bacteria Salmonella typhi, Proteus vulgaris, Shigella flexniu and Micrococos luteus. Extraction was carried out using maceration method, methanol and chloroform extracts was obtained. Antimicrobial activities of the final extracts was tested using two methods agar disk diffusion method and serial tube dilution method (in order to determine) Minimum Inhibitory Concentration (MIC). Results: Results of bioassay showed the tested macroalgae exhibited the highest antibacterial activity against Gram- negative bacteria, S. typhi and Gram- negative bacteria M. Luteus exhibited the highest resistant against algal extracts. Conclusion: red alga L. snyderiae exhibited higher antibacterial activity than brown alga S. angustifolium against tested bacteria strains.}, Keywords = {laurencia snyderiae, sargassum angustifolium, antibacterial activity, MIC}, volume = {14}, Number = {1}, pages = {17-22}, publisher = {Bushehr University of Medical Sciences}, url = {http://ismj.bpums.ac.ir/article-1-240-en.html}, eprint = {http://ismj.bpums.ac.ir/article-1-240-en.pdf}, journal = {Iranian South Medical Journal}, issn = {1735-4374}, eissn = {1735-6954}, year = {2011} } @article{ author = {Ravanipour, Masoumeh and RezaieKalantary, Roshanak and Farzadkia, Mehdi and HashemiNajafAbadi, Samireh}, title = {Determine the Efficacy of Salinity on Bioremediation of Polluted Soil by Phenanthrene}, abstract ={Background: Phenanthrene is one of the Polycyclic Aromatic Hydrocarbons (PAHs) that are formed during the incomplete combustion of fossil fuels, oil pollution and different process of oil and gas plants. PAHs-contaminated area have increased a health risk to humans and environments due to toxicity, carcinogenicity, hydrophobicity and their tendency to accumulation in soil and sediment and their entrance to food chain. Bioremediation is an effective method for removing toxic pollutants from soils such as Phenanthrene. The main object of this study is the assessment of the effects of salinity on the efficacy of the process of bioremediation on polluted soils by Phenanthrene. Methods: The bare soil of any organic and microbial pollution was first polluted artificially to the phenanthrene then a nutrient solution with two minimum and maximum concentrations of salinity were added to it in order to have the proportion of 10% w:v (soil: water). After that a microbial mixture which was enable degradation the phenanthrene added to the slurry and aerated. After the extraction of phenanthrene by ultrasonic, the residual concentration in the soil was analyzed by GC. Results: In the conditions that salinity concentration was maximum, the microbial growth has a longer lag phase than the minimum salinity. The findings from extraction process by GC depict the removal percentage of maximum and minimum salinity in 56th %70.5 day and %71.8, respectively. Conclusion: In In spite of the longer log phase of maximum concentration of salinity and according to GC results, there was just a little difference between two solutions. Therefore it reveals that salinity can increase the lag phase but haven't any inhibitory effect on Phenanthrene removal.}, Keywords = {soil pollution, PAHs, bioremediation, salinity}, volume = {14}, Number = {1}, pages = {23-30}, publisher = {Bushehr University of Medical Sciences}, url = {http://ismj.bpums.ac.ir/article-1-241-en.html}, eprint = {http://ismj.bpums.ac.ir/article-1-241-en.pdf}, journal = {Iranian South Medical Journal}, issn = {1735-4374}, eissn = {1735-6954}, year = {2011} } @article{ author = {Forouzani, Abdolrasoul and Khajehiean, Abdolmohamamd and Darabi, Hossein and Fouladvand, Morad Ali and Nabipour, Iraj and Bahramian, Fatemeh}, title = {Fauna and Monthly Activity of Sand flies in The Focus of Cutaneous Leishmaniasis in Bushehr District (2007-2008)}, abstract ={Background: Cutaneous Leishmaniasis is one of the endemic diseases in Bushehr Province, which its prevalence has increased in some districts, as well as Bushehr district recently. This is essential to access minute information about epidemiology of diseases (Parasite, Vector, Reservior), in order to achieve effective control of disease. One of the basic information in respect of controlling measures, is the knowledge and information of fauna and monthly activities of vectors which is essential, because ignoring of different biological aspects of vectors, could cause failure to control strategies. Methods: This is a descriptive- cross sectional study, carried out in four villages of Bushehr district (2007-2008) which were affected by cutaneous Leishmaniasis. Sand flies were collected by standard sticky traps, and identified by electric microscope, using reliable identification keys. Results: Sixteen species. (six Phelebotomus and ten Sergentomyia) were identified from a total of 15952 sand flies caught for this study, out of which eight species are reported for the first time in Bushehr district, namely: Phelobotomus mongolensis, P.caucasicus, P.ansari, Sergentomyia tiberiadis, S.clydei, S.antenata, S.iranica, S.palestiensis. Monthly activity of sand flies starts in mid March and ends by the end of December. The peack of sand flies monthly activities is in June, while the peack activity of P.papatasi is in the end of July. Conclusion: Considering nine months activity period of sand flies in Bushehr district, and their peack of activities, specially for P.paptasi, it is suggested that the controlling measures to be administrated in July.}, Keywords = {leishmaniasis, phlebetomus, sand fly, Bushehr }, volume = {14}, Number = {1}, pages = {31-40}, publisher = {Bushehr University of Medical Sciences}, url = {http://ismj.bpums.ac.ir/article-1-242-en.html}, eprint = {http://ismj.bpums.ac.ir/article-1-242-en.pdf}, journal = {Iranian South Medical Journal}, issn = {1735-4374}, eissn = {1735-6954}, year = {2011} } @article{ author = {Saberi, Hamidreza and Moraveji, Alireza and Naseh, Jav}, title = {Occupational Burnout among School Teachers and some Related Factors in Kashan 2007}, abstract ={Background: Occupational burnout is considered as side effect of occupational stress. It includes some mental, functional, and personal characteristics in which a person has some symptoms of them. Occupational burnout can be caused in all jobs therefore, diminishes performance and utilization, depression and disease. Due to the important role of teachers, this study was conducted to asses the occupational burnout in teachers in Kashan. Methods: This study was carried by Maslach standard questionnaires on 385 teachers and justify teachers under study in three fields: depersonalization, emotional exhaustion, diminished performance, and occupational burnout of was assessed by standard scorning. Results: The results indicated that the majority of school teachers had burnout in both internal and external dimensions in mild level. In this study three dimensions of burnoutwere: Depersonalization(mild84.5%,moderate10.9%,sever4.6%),emotional exhaustion (mild 71.9%, moderate 18%, sever10.1%),diminished performance(mild86.7%,moderate11.1%,sever2.2%) negative significant association was founded with increasing age(p=0.002) and duration of work years(p=0.001) and burnout. We founded that positive significant association with increasing educational degree(p<0.05),gender (p<0.01), kind of house(p=0.003), psychological disorders(p=0.02), family dissatisfaction(p=0.031) and teacher’s burnout. Conclusion: It seems that most people under study had mild occupational burnout, and acute occupational burnout was observed in some teachers (depersonalization 15.4%, emotional exhaustion28.1%) that need to more attention to them, because the role of teachers in our country is very important.}, Keywords = {occupational burnout, teachers, depersonalization, maslach}, volume = {14}, Number = {1}, pages = {41-50}, publisher = {Bushehr University of Medical Sciences}, url = {http://ismj.bpums.ac.ir/article-1-243-en.html}, eprint = {http://ismj.bpums.ac.ir/article-1-243-en.pdf}, journal = {Iranian South Medical Journal}, issn = {1735-4374}, eissn = {1735-6954}, year = {2011} } @article{ author = {KalantarHormozi, Mohammad Reza and Nabipour, Iraj and Assadi, Majid and Asadipouya, Kamyar and Zendehboudi, Soudabeh and RanjbarOmrani, Gholamhosei}, title = {Subclinical Hypothyroid}, abstract ={Background: subclnical hypothyroid (SCH), defined by a normal total or free T4 level and a midly Elevated TSH, is common in adults. Subclinical hypothyroid is a risk factor for developing hypothyroidism complication . the goal of screening is to identify and treatment patients with sublinical hypothyroid before they develop these complication. Methods: The sample size of this study was the articles indexed in pubmed,ovid, tripdatabase, new spring link black coehrane, Elsevirer, Embase and contained the terms subclinical hypothyroid, Anti-tpo, Thyrotropin, levothyroxine trapy. Results: 831 articles were found that 75 articles were investigated for this issue. The results are discussed under. The subtile such as subclinical hypothyroid, screening for subclinical hypothyroid, Indication of treatment of Subclinical hypothyroid. Conclusion: In this summary, we tried to review the current literature about definition, Indection of screening and treatment of subclinical hypothyroid and reach a comprehensive guidline for practical significance of this subject in routines practice.}, Keywords = {subclinical hypothyroid, Anti-TPO, thyrotropin, levothyroxine tropy}, volume = {14}, Number = {1}, pages = {51-60}, publisher = {Bushehr University of Medical Sciences}, url = {http://ismj.bpums.ac.ir/article-1-244-en.html}, eprint = {http://ismj.bpums.ac.ir/article-1-244-en.pdf}, journal = {Iranian South Medical Journal}, issn = {1735-4374}, eissn = {1735-6954}, year = {2011} } @article{ author = {Sarmadian, Hossein and Dalvandi, Mohsen and Ghasemikhah, Reza and Mehrian, Payam and Assadi, Maji}, title = {Cerebral Hydrated Disease in a Patient with Behcet,s Syndrome: A Case Report}, abstract ={Hydatid cyst is a zoonotic infection caused by the larval stage of the worm Echinococcus granulosus. Although any organ could be infected, the involvement of the bone, brain and heart are uncommon. The brain involvement Prevalence varies in the hydatid disease. We present a 27-year-old man with 10 years history of Behcet disease and with an unusual occurrence of brain hydatidosis, diagnosed by MRI and histological findings. Removal of the cyst by surgery was successfully performed and Albendazole was administered for 4 weeks after the surgery (400 mg two times daily) accompanied MLP.}, Keywords = {brain hydatid cyst, albendazole, MRI, behcet}, volume = {14}, Number = {1}, pages = {61-64}, publisher = {Bushehr University of Medical Sciences}, url = {http://ismj.bpums.ac.ir/article-1-245-en.html}, eprint = {http://ismj.bpums.ac.ir/article-1-245-en.pdf}, journal = {Iranian South Medical Journal}, issn = {1735-4374}, eissn = {1735-6954}, year = {2011} } @article{ author = {Assadi, Majid and Moslehi, Masoo}, title = {Cardiac & Lung Nuclear Medicine Exams}, abstract ={This book has three chapters: Heart, lung and radiation protection. In each chapter, indications of scans, radiopharaceuticals the study performance, patient preparation, report and also possible problems were discussed. In addition, in the end of each chapter, many mutliplechoice question (MCa) were expressed. The studying of this book for at medical students, physicians and colleagues is recommended.}, Keywords = {}, volume = {14}, Number = {1}, pages = {65-65}, publisher = {Bushehr University of Medical Sciences}, url = {http://ismj.bpums.ac.ir/article-1-246-en.html}, eprint = {http://ismj.bpums.ac.ir/article-1-246-en.pdf}, journal = {Iranian South Medical Journal}, issn = {1735-4374}, eissn = {1735-6954}, year = {2011} } @article{ author = {Kargar, Mohammad and Daneshvar, Mousa and Homayoun, Maryam}, title = {Surveillance of Virulence Markers and Antibiotic Resistance of Shiga toxin Producing E.coli O157:H7 Strains from Meats Purchase in Shiraz}, abstract ={Background: Shiga toxin Producing Escherichia coli O157:H7 is a common pathogen in cattle, which occasional causes some human disease. This bacterium can potentially contaminate meat and clinical cases of E.coli O157:H7 infections are often associated with consumption of undercooked ground beef. Methods: In this cross-sectional study 122 samples of ground meat were collected and after enrichment in specific culture media and evaluation sorbitol fermentation and their &beta;-glucoronidase activity, the isolation of E.coli O157:H7 strains have been confirmed with specific antisera. Then virulence genes verotoxin, intimin and hemolysin with multiplex PCR and antibiotic resistance strains with disk diffusion method have been tested. Results: Out of specimens that have been supplied, 119 sorbitol negative colonies isolated which 3 strains O157:H7 (2.45%) with specific antisera confirmed. Out of considered virulence genes, in two cases of these samples (1.64%) the stx1 and eaeA genes were seen and also 2 isolated bacteria had resistance to erythromycin, tetracycline, ampicillin, penicillin, clindamicin, cefixime, novobiocin, and gentamicin antibiotics. Conclusion: As this organism lives in intestines of healthy cattle, preventive measures on cattle farms and during meat processing are necessary.}, Keywords = {escherichia coli O157:H7, shiga toxin , antibiotic resistance, meat O157:H7, shiga toxin, antibiotic resistance, meat }, volume = {14}, Number = {2}, pages = {76-83}, publisher = {Bushehr University of Medical Sciences}, url = {http://ismj.bpums.ac.ir/article-1-253-en.html}, eprint = {http://ismj.bpums.ac.ir/article-1-253-en.pdf}, journal = {Iranian South Medical Journal}, issn = {1735-4374}, eissn = {1735-6954}, year = {2011} } @article{ author = {Yaghoubi, Ramin and Mirzaie, Mitra and Ramzi, Mani and ShahIli, Marj}, title = {Determination of the Prevalence of HGV Infection in Leukemia Patients}, abstract ={Background: The potential of acute and chronic viral hepatitis infections in blood leukocytes is one of the possible risk factors of leukemia. Between hepatitis viruses, HGV is important for unknown mechanism of pathogenesis in affecting the outcome of leukemia. In this research the prevalence of HGV infection was studied for evaluation of the possible role of this viral infection in the pathophysiology of leukemia. Methods: In this study, 100 EDTA treated blood samples were collected for 2 and half a year from different types of leukemia and also healthy control group, respectively. The plasma of these blood samples were harvested and stored at -80°C till laboratory tests were performed. Serological and antigenic markers of HBV, HCV and HGV were analyzed by ELISA methods. The HGV viremia was also studied by an in-house nested-RT-PCR method in plasma samples of patients with leukemia and control population. Results: Anti-E2-Ab was detected in 1(1%) of leukemia patients who has not the history of HBV and HCV infections. HGV-RNA was diagnosed in 4(4%) of patients with leukemia and 1(1%) of control group. Simultaneous infection of HGV-RNA and HBsAg was detected in one of patients with leukemia. Significant difference was seen between the prevalence of HBV infection in leukemia patients and control group (P=0.02). Also significant correlation was detected between sex and the prevalence of HBV infection in leukemia patients (P=0.02). None of studied risk factors of leukemia were not significantly correlated with HGV infection. Conclusion: In this study the low prevalence of active and persistent HGV infections in leukemia patients in comparing with control population was confirmed. Also detection of HGV and HBV co-infection in these patients, announced the need of completed studies in different populations with different hematological malignancies and/or abnormalities, for better therapeutic and laboratory management of these cancers.}, Keywords = {HGV, HCV, HBV, leukemia }, volume = {14}, Number = {2}, pages = {84-93}, publisher = {Bushehr University of Medical Sciences}, url = {http://ismj.bpums.ac.ir/article-1-254-en.html}, eprint = {http://ismj.bpums.ac.ir/article-1-254-en.pdf}, journal = {Iranian South Medical Journal}, issn = {1735-4374}, eissn = {1735-6954}, year = {2011} } @article{ author = {Shojapour, Mana and Validi, Majid and Shariaty, Laleh and Karimi, Ali and Zamanzad, Behnam}, title = {Determination of antimicrobial resistance pattern and Extended-Spectrum Beta Lactamases producing Pseudomonas aeruginosa strains isolated from clinical specimens of Hajar and Kashani Hospitals,Shahrekord 1387}, abstract ={Background: Pseudomonas aeruginosa is one of the leading causes of hospital infections in patients hospitalized for a 10 day period or over. It is also considered to be the most important cause of the burn wound infection. Approximately 75% of deaths in burned patients are due to wound infection and the subsequent septicemia. Clinical use of antibiotics has increasingly led to the global distribution of P. aeruginosa isolates with multi-drug resistance. The study was launched to determine the antimicrobial susceptibility pattern and the presence of the extended-spectrum-beta lactamase (ESBL) in P.aeruginosa strains isolated from clinical specimens. Methods: Totally, 175 P. aeruginosa strains were isolated from clinical samples and identified by standard methods. The pattern of antimicrobial resistance was then performed on the isolates using Disk Agar Diffusion (DAD) according to CLSI Guideline. Primary screening test for ESBL producing strains was performed by ceftazidim antibiotic disk using disk diffusion method. Combined disk method was used to confirm ESBL producing bacteria. Results: The rate of antimicrobial resistance of P.aeruginosa isolates were 64% to ticarcillin, 52.2% to cefepime, 68.6% to ticarcillin/clavolanic acid, 68.6% to ceftazidime, 67.4% to amikacin, 68.6% to gentamicin, 48% to imipenem, 77.7% to ciprofloxacin and 5.1% to polymixcine B. In the primary screening test, 120 isolates of P.aeruginosa strains were resistant to ceftazidime. In the combined disk method, 66 isolates (55%) were positive for ESBLs. Conclusion: Polymixcine B was found to be the most effective antimicrobial agent in this study. Bacteria carrying ESBL genes may increase mortality and morbidity. Thus, their accurate diagnosis is of extreme importance to prevent from the treatment failure resulted from improper antibiotic administration.}, Keywords = {antibiotic resistance, combined disk method, ESBLs, pseudomonas aeruginosa}, volume = {14}, Number = {2}, pages = {94-99}, publisher = {Bushehr University of Medical Sciences}, url = {http://ismj.bpums.ac.ir/article-1-255-en.html}, eprint = {http://ismj.bpums.ac.ir/article-1-255-en.pdf}, journal = {Iranian South Medical Journal}, issn = {1735-4374}, eissn = {1735-6954}, year = {2011} } @article{ author = {Movahed, Ali and Mohammadi, Mohamad Mehdi and Akbarzadeh, Samad and Nabipour, Iraj and Ramezanian, Nader and Hajian, Najmeh}, title = {The heart of date palm: its nutritional and functional constituents}, abstract ={Background: The date palm (Phoenix dactylifera L.) is one of the three important fruit crops in the palm family. Kabkub is the main cultivated species in southern part of Iran, Bushehr. Every part of this tree has its own uses. The tree's terminal buds (heart of palm or palmitos) are believed to have many nutritional values. As a folk medicine, it has been used for the improvement of stamina and treatment of sexual weakness. In order to evaluate the nutritional values of this product of date palm, we analyzed the total carbohydrates, proteins, minerals, and fats in the sample. Methods: The palm hearts were obtained from local trees, minced, dried, and ground to powder. Fats were extracted and analyzed using Bligh-Dyer method and gas chromatography. Total proteins and carbohydrates were determined by Kjeldahl and Lane-Eynon methods, respectively. The minerals were analyzed by atomic absorption spectroscopy. Results: The total fat content of the sample was 0.27g/28g. The unsaturated fatty acids present in the sample were mainly linoleic, linolenic and oleic acids, all together comprised 27.2% of the fats. Palmitic acid was the main saturated fat. The total protein estimated was 0.3g/28g. The carbohydrate content of the palm heart was 2.29 g and the minerals present in the sample were mainly Zn, Fe, Mg, P, Mn, Ca, Cu, Na, K, and Se. Conclusion: Date palm contains many essential fatty acids and known anti-inflammatory nutrients including zinc. The amount of crude fiber present in the heart of palm makes it as a valuable dietary product to be used as a tasty fat-cholesterol free nutrient.}, Keywords = {date palm, Kabkub, palmitos, palm heart, nutritional values }, volume = {14}, Number = {2}, pages = {100-105}, publisher = {Bushehr University of Medical Sciences}, url = {http://ismj.bpums.ac.ir/article-1-256-en.html}, eprint = {http://ismj.bpums.ac.ir/article-1-256-en.pdf}, journal = {Iranian South Medical Journal}, issn = {1735-4374}, eissn = {1735-6954}, year = {2011} } @article{ author = {Parsi, Behz}, title = {Determining the pulmonary function test indices in the labors at school equipment manufacturing company in Sari-Iran in 2008}, abstract ={Background: Occupational respiratory exposure with the hazardous lead to the onset of various complications in man. Screening of the labors in the manufacturing companies is the main procedure of controlling the incidence of such problems. In this study we aimed to evaluate the spirometry indices in the labors at the school equipments manufacturing factory in Sari, Iran and investigate the frequency of abnormal spirometry parameters, and an early identification of labors at risk of pulmonary diseases. Methods: In this descriptive study, all of the 133 male workers at risk of pulmonary exposure to hazardous air dusts were taken for the study by census method. After clinical examination and filling the provided questionnaire, the pulmonary function tests by spirometry based on the American Thoracic Association (ATA) in the subjects under study were performed. The Forced Expiratory Volume in First Second, Forced Vital Capacity (FEV1, FVC) and the FEV1/ FVC ratio were recorded. Results: The clinical symptoms indicating the pulmonary conditions were not observed in any of the subjects under study but the data of spirometry of the subject separately indicated reduced of FVC criteria in five cases, and in two of them reduction of both FEV1 and FVC indices, compared to the standard levels was observed. Insignificant difference between the criteria of spirometry and body mass index (BMI), smoking, the workplace and working experience was observed. Conclusion: Though no relation was observed between spirometry criteria disorders and smoking, work experience and workplace, but in seven cases spirometry indices disorder without clinical symptoms was observed. These subjects identified as the risk individuals.}, Keywords = {pulmonary function test, school equipments manufacturing company, occupational health, Cigarette Smoking }, volume = {14}, Number = {2}, pages = {106-113}, publisher = {Bushehr University of Medical Sciences}, url = {http://ismj.bpums.ac.ir/article-1-257-en.html}, eprint = {http://ismj.bpums.ac.ir/article-1-257-en.pdf}, journal = {Iranian South Medical Journal}, issn = {1735-4374}, eissn = {1735-6954}, year = {2011} } @article{ author = {Rajaiefard, Abdolreza and Moghimi, Bijan and Tabatabaie, Seyed Hamidreza and Safaie, Azadeh and Tabeie, Seyed Ziadi}, title = {Epidemiological and clinical features of gastric cancer: descriptive study of cancer registry cases of Fars province (2001-2006)}, abstract ={Background: Cancer diseases especially gastric cancer is one of the most important problems in Iran and many other countries. Whereas, determination of epidemiological characteristics of gastric cancer is very important, this study carried out with the aim of epidemiologic survey of gastric cancer in Fars province. Methods: This study was performed on total gastric cancer cases that registered in Tumor Registry Center of Fars province between2001-2006. Necessary information was gathered from cancer registry forms and hospital files. All statistical analysis was performed by using SPSS (V.13) software. Results: Of 442 gastric cancer patients 68.6% were males and 31.4% were females. Mean age at diagnosis was 58.4 years (SD=14.46), for men 60.72 years (SD=13.82) and for women 53.29 years (SD=14.48). In total, 91.5% of patients were married, most of men were farmer and greatest parts of women were housewife. History of smoking reported by 52.8% of cases. Most prevalent clinical finding in patients were epigastric pain, loss weight and loss appetite, respectively. In 74% of patients, time interval between beginnings of first symptoms until diagnosis of disease was more than one month and in 40.7% of cases, grade of tumor at diagnosis time was poorly differentiated. Conclusion: According to these results, deduction of risk factors and early detection in at risk subjects such as smokers, high risk occupations and individuals with family history of cancer, is important for prevention and control of gastric cancer.}, Keywords = {epidemiology, gastric cancer, descriptive-analytic study, Cigarette Smoking, Cancer Registry, Fars Province }, volume = {14}, Number = {2}, pages = {114-121}, publisher = {Bushehr University of Medical Sciences}, url = {http://ismj.bpums.ac.ir/article-1-258-en.html}, eprint = {http://ismj.bpums.ac.ir/article-1-258-en.pdf}, journal = {Iranian South Medical Journal}, issn = {1735-4374}, eissn = {1735-6954}, year = {2011} } @article{ author = {Fard-fahani, Armaghan and Beiki, Davood and Fallahi, Babak and Emami-Ardakani, Alireza and Saghari, Mohsen and Eftekhary, Mohamm}, title = {Neuroendocrine tumors treatment with I-131 Metaiodobenzylguanidine (MIBG)}, abstract ={Background: I-131 Metaiodobenzylguanidine (MIBG) is a radiopharmaceutical which is proved effective in treatment of tumors with neuroendocrine origin, especially the neuroectodermal (sympathoadrenal) type, including pheochromocytoma, paraganglioma and neuroblastoma. It is also of some value in other neuroendocrine tumors (mainly carcinoid and medullary carcinoma of thyroid). Methods: The method employed in this research was a systematic bibliographic review, in which only valid studies or the clinically detailed enough open-labeled studies using validated scales were used. Results: I-131 MIBG is the best nonsurgical method for treatment of pheochromocytoma. It not only increases survival, but also significantly improves patients’ symptoms (75-90%). Although the efficacy of this method for refractory or relapsing neuroblastoma has been 30%, adding other treatment modalities increases the impact of this treatment. For other neuroendocrine tumors including carcinoid tumor and medullary carcinoma of thyroid, MIBG therapy has been effective in reducing patients’ symptoms. The most important complication of this method is myelosuppression which needs follow-up and if necessary relevant treatment. Conclusion: I-131 MIBG has an important role in treatment of chromafin tumors. For pheochromocytoma and neuroblastoma it is the best nonsurgical treatment. It is effective in neuroblastoma especially if it is used in conjunction with other treatment modalities. I-131 MIBG can also diminish symptoms of carcinoid tumor and medullary thyroid carcinoma efficiently.}, Keywords = {pheochromocytoma, neuroblastoma, I-131 MIBG, carcinoid tumor, medullary thyroid carcinoma, neuroendocrine tumors }, volume = {14}, Number = {2}, pages = {122-133}, publisher = {Bushehr University of Medical Sciences}, url = {http://ismj.bpums.ac.ir/article-1-259-en.html}, eprint = {http://ismj.bpums.ac.ir/article-1-259-en.pdf}, journal = {Iranian South Medical Journal}, issn = {1735-4374}, eissn = {1735-6954}, year = {2011} } @article{ author = {Alizadeh-Otaghvar, Hamidreza and Firoozbakht, Saeedeh and Montazeri, Sahar and Khazraie, Samaneh and BaniAhmad, Marjan and Hajiloo, Maryam}, title = {A Remarkable Improvement of Patients with Idiopathic Thrombocytopenic Purpura after appendectomy including Carcinoid tumor}, abstract ={The assistance of chronic idiopathic thrombocytopenic purpura and appendiceal carcinoid tumor is so rare and has not been reported before .we present here in a 11 year old boy that is the known case of chronic idiopathic thrombocytopenic purpura (with the platelet count of 20000 when admitted). He reffered due to anorexia, pain and tenderness of right lower quadrant of abdomen and vomiting. He also had leukocytosis and abdominal free fluid in sonographic report. These findings suggested the diagnosis of acute appendicitis and the patient underwent appendectomy, after the operation, the platelet count became normal. The pathologic report of the specimen of the appendix was carcinoid tumor. Now the question is whether the appendiceal carcinoid tumor can be the reason of symptoms of chronic idiopathic.}, Keywords = {chronic idiopathic thrombocytopenic purpura, acute appendicitis, carcinoid tumor, appendectomy }, volume = {14}, Number = {2}, pages = {134-139}, publisher = {Bushehr University of Medical Sciences}, url = {http://ismj.bpums.ac.ir/article-1-260-en.html}, eprint = {http://ismj.bpums.ac.ir/article-1-260-en.pdf}, journal = {Iranian South Medical Journal}, issn = {1735-4374}, eissn = {1735-6954}, year = {2011} } @article{ author = {Ravanipour, Maryam}, title = {A Review on Ageing with Empowerment Approach}, abstract ={Older adult population is being increased in Iran as well as in the world. Power is a resource for living that is present in all individuals, and has a positively uplifting effect on quality of life. In this book it will be reviewed the ageing theories, successful ageing, self care in ageing, some problems in this age, factors influences on sense of power and empowerment, concept of power, empowerment theories and manifestations and outcomes of powerlessness and finally empowerment process. Studying of this book for policymakers, students, and colleagues is recommended.}, Keywords = {No Keyword}, volume = {14}, Number = {2}, pages = {140-140}, publisher = {Bushehr University of Medical Sciences}, url = {http://ismj.bpums.ac.ir/article-1-261-en.html}, eprint = {http://ismj.bpums.ac.ir/article-1-261-en.pdf}, journal = {Iranian South Medical Journal}, issn = {1735-4374}, eissn = {1735-6954}, year = {2011} } @article{ author = {AliSaeedi, Alireza and Sadeghi, Masoomeh and Saneie, Hamid and Ramezani, Mohammad Arash and Sarrafzadegan, Nazal}, title = {The Comparison of serum inflammatory markers E-selection and Interlokin-6 in patient with acute coronary syndrome and stable angina}, abstract ={Background: It is stabilized that one of Atherosclerosis cause is an inflammatory phenomenon. E selectin and interleukin 6 (IL-6) are the sensitive markers of systemic inflammation. The aim of this study was to compare the serum level of this cytokines between acute coronary syndrome (ACS) and stable angina (SA) patients, and define relation between serum level of these cytokines and plaque complication. Methods: The patients were selected consequently and all of them were male. The mean age of patients was 56/3±9/4 years and there was no significant difference in mean age between two groups.. The patients with ACS were recruited in first group. In contrast SA patients were put in the second group. Coronary angiography was done for all patients. The serum E-selectin and interleukin-6 were assessed by ELIZA methods. At the end data were analyzed by T test and ANCOVA model. Results: The mean of total cholesterol and LDL cholesterol were higher in SA patients significantly. The average of serum E-selectin in ACS was 53/4±25/7 mg/dl and in SA group was 49/4±23/7 mg/dl. The mean of IL-6 were 101/6±190/7 vs 226/9±366 in two groups consequently. There was statistically significant difference in mean of IL-6 between two group (t=2/869, p=0.005), but no in E-selectin serum level. Conclusion: Our data showed no significant difference between ACS and SA patients in E-selectin serum level, but mean of serum IL-6 was higher in SA patients. It is considered that inflammatory process has essential role in chronic atherosclerosis.}, Keywords = {E-selectin, interleukin-6, acute coronary syndrome, stable angina }, volume = {14}, Number = {3}, pages = {151-158}, publisher = {Bushehr University of Medical Sciences}, url = {http://ismj.bpums.ac.ir/article-1-268-en.html}, eprint = {http://ismj.bpums.ac.ir/article-1-268-en.pdf}, journal = {Iranian South Medical Journal}, issn = {1735-4374}, eissn = {1735-6954}, year = {2011} } @article{ author = {Shemirani, Hasan and Nekooie, Fatemeh and Pourmoghaddas, Masoo}, title = {The Role Of Inflammation In Stent Restenosis More Than 1 Year Afetr Drug Eluting Stent Implantation}, abstract ={Background: In stent restenosis (ISR) following endovascular interventions is the main limitation of their long-term success. Despite advances have been made during recent years to decrease restenosis, it remains a challenging clinical problem.The aim of this study was to evaluate the relationship between angiographic coronary in stent restenosis, inflammation after successful stent implantation. Methods: This study included 78 patients, 35year old and higher who underwent coronary angiography more than 1 year after drug-eluting stent (DES) implantation because of symptoms suggestive ischemia. Patients were divided into ISR group (case) and patent stent group (control) according to angiography results. For all patients blood lipids and high sensitivity C-Reactive Protein (hsCRP) were measured simultaneously. Results: Age, sex, hypertension, current smoking, and lipid profile other than High Density Lipoprotein (HDL-C) of patients in the case and control groups were similar .However, HDL-C < 40mg/L was more prevalent with ISR (66.7% vs. 30.8%, p=0.002). The hsCRP level was 2.98±2.06 mg/L in the case group and 2.50±1.80 mg/L in the control group. There were no significant differences in mean hsCRP concentration between the two groups (p=0.14), however mean hsCRP level was significantly higher in men of case group than control group (3.35mg/L vs. 2.21mg/L, p<0.05). Conclusion: This study demonstrates that in men but not in women inflammation may be a predictor of in stent restenosis more than 1 year after drug eluting stent implantation. Also, high-density lipoprotein (HDL) probably has protective effect against stent restenosis.}, Keywords = {coronary restenosis, C-reactive protein, drug-eluting stent, inflammation}, volume = {14}, Number = {3}, pages = {159-164}, publisher = {Bushehr University of Medical Sciences}, url = {http://ismj.bpums.ac.ir/article-1-269-en.html}, eprint = {http://ismj.bpums.ac.ir/article-1-269-en.pdf}, journal = {Iranian South Medical Journal}, issn = {1735-4374}, eissn = {1735-6954}, year = {2011} } @article{ author = {Shariaty, Laleh and Shojapour, Mana and Validi, Majid and Farrokhi, Effate and Tabatabaiefar, Mohammad Amin and Karimi, Ali and Nafisi, Mohammadrez}, title = {The investigation of prevalence of methicillin and vancomycin resistance in coagulase negative Staphylococci isolated from clinical samples of Shahrekord university hospitals, 2009}, abstract ={Background: Vancomycin has been widely used in the treatment of infections caused by methicillin-resistant coagulase negative Staphylococci (MRCoNS). The emergence of vancomycin-intermediate and -resistant coagulase negative Staphylococci (VICoNS and VRCoNS, respectively) in various parts of the world, has caused great concern. In this study we investigated the prevalence of MRCoNS and Emergence of VICoNS and VRCoNS in Shahrekord Hospitals. Methods: Eighty eight coagulase negative Staphylococcus isolates were identified out of 284 Staphylococcus isolates collected from Shahrekod’s hospitals, Then, antimicrobial susceptibility pattern was determined for 12 antibiotics with Disk Diffusion method. Methicillin resistant strains were identified by several methods: Disk diffusion, E-test and Real-time PCR. Vancomycin resistant strains were also identified by several methods: Disk diffusion, Agar screening, E-test and Duplex PCR. Results: Using the disk diffusion test, 100% of isolates were resistant to penicillin while the lowest resistance (33%) was found for ofloxacin. Fourty six CoNS strains were methicillin resistant and none of these isolates were vancomycin resistant and none had vanA/vanB genes demonstrated by PCR. Conclusion: This study showed a high prevalence of MRCoNS at Shahrekord hospitals, but, vancomycin resistance was not found.}, Keywords = {coagulase negative Staphylococci, vancomycin resistance, methicillin resistance, prevalence }, volume = {14}, Number = {3}, pages = {165-172}, publisher = {Bushehr University of Medical Sciences}, url = {http://ismj.bpums.ac.ir/article-1-270-en.html}, eprint = {http://ismj.bpums.ac.ir/article-1-270-en.pdf}, journal = {Iranian South Medical Journal}, issn = {1735-4374}, eissn = {1735-6954}, year = {2011} } @article{ author = {Soufian, Masoomeh and Mahdaviani, Fatemeh Sadat and Izadi, Nabiollah and Mousavinejad, Ali and Sarmadian, Hossein and Zarrinfar, Nader and Kahbazi, Manizheh and Farazi, Ali Asghar}, title = {Comparison the prevalence of isolated Hepatitis B core antibody among injection drug users with blood donors in central province in IRAN}, abstract ={Background: In healthy blood donors, 2%–5% have isolated anti-HBc. Prevalence of hepatitis B, C and co- infection (HBV +HCV) among injection drug user is high. Hepatitis C suppress of HB SAg and may be hepatitis B presented only with isolated anti HBC. This study determined of prevalence of isolated anti HBC among injection drug users and compare with blood donors in Arak city. Methods: A total 684 subjects (531voluntary blood donors and 153 injection drug users) in Arak, Iran were included in this study. Hepatitis B surface antigen (HBsAg), hepatitis B surface antibody (anti-HBs), anti-HBc, and hepatitis C antibody (anti-HCV) were tested in all subjects. Results: A total of 531 voluntary blood donors living in the city of Arak, in the Central Province of Iran, with a mean age of 36 ± 10.18 years (range 16–60 years) were enrolled in the study. Ninety-three percent of patients were male and 7% were female. Of the 531 cases, 11 subjects (2.1%) had isolated anti-HBc. A total of 153 injection drug users of Arak, in the Central Province of Iran, with a mean age of 30.66 ± 5.92 years (range 20-50 years) were enrolled in the study. All of them were male. Of the 153 cases, 12 subjects (7.84%) had isolated anti-HBc. All of 12 cases were HCV positive. Conclusion: Prevalence of isolated anti-HBc among injection drug users was 3. 73 fold in comparison with blood donors. For diagnosis of hepatitis B in this group test for anti-HBc will be done. Evaluation of occult hepatitis B in subject with isolated anti-HBc by exact method such as real time PCR is necessary.}, Keywords = {isolated anti-HBc, injection drug users, prevalence, hepatitis }, volume = {14}, Number = {3}, pages = {173-178}, publisher = {Bushehr University of Medical Sciences}, url = {http://ismj.bpums.ac.ir/article-1-271-en.html}, eprint = {http://ismj.bpums.ac.ir/article-1-271-en.pdf}, journal = {Iranian South Medical Journal}, issn = {1735-4374}, eissn = {1735-6954}, year = {2011} } @article{ author = {Aghajanzadeh, Manouchehr and Roudbari, Seyed Ali and Khadem, Shahram and Sakhabakhsh, Mehdi and Emami, Dina and Masahnia, Sar}, title = {The role of Thymectomy in Remission of Myasthenia gravis patients with or without Thymoma}, abstract ={Background: Myasthenia gravis is an auto immune disease thymus have important role in this disease which Thymoma is the primary tumor of thymus that is produced by augmentation of epithelial cells inside of Glands. Thymectomy can improved myasthenia gravis disease. The main aim of this study is to assess the remission among the myasthenic patients after thymectomy. Methods: From 1993 to 2004, 68 patients who underwent thymectomy for mysthenia gravis were studied. Myathenia was established by positive electromyography and tensilon tests. These patients were operated by one surgeon at teaching and private hospitals, the specimens were tested by pathologist and patients were under follow up for 12 to 48 months. In following- up time the patient’s answer to remedy was basis to daily use of Mestinone and myasthenia crisis was investigated. Results: The age of the patients was 14 to 60years. The average age of the patients who was 34/08 years old. In 42 of patients was female and 26 was men. Between the men, 11 had complete remission 14 partial remission and one no answer. Between the female, 21 had complete remission. 19 partial remission and 2 no answer. This study had no inhospital mortality, but in follow up we 4/4% mortality seen. In pathology studies, 21 patients had thymoma, 45 had hyperplasia, and 2 had normal thymus. In 21 patients with thymoma, 11 had complete remission, 10 partial remissions. Between 45 patients with hyperplasia, 20 complete remission, 22 partial remission and 3 no answer. From two normal pathology reports, 1 complete and one partial remission. Conclusion: We conclude that thymectomy is a beneficial procedure for myasthenia gravis patients with a complete clinical remission rate in our series. Therefore we conclude thymectomy for myasthenia gravis patients is indicated as early as possible in the course of disease.}, Keywords = {myasthenia gravis, thymectomy, thymoma, hyperplasia, remission }, volume = {14}, Number = {3}, pages = {179-184}, publisher = {Bushehr University of Medical Sciences}, url = {http://ismj.bpums.ac.ir/article-1-272-en.html}, eprint = {http://ismj.bpums.ac.ir/article-1-272-en.pdf}, journal = {Iranian South Medical Journal}, issn = {1735-4374}, eissn = {1735-6954}, year = {2011} } @article{ author = {Khoramroudi, Rozita and Norouzi, Azita and Jamand, Tayebeh and Tahmasebi, Rahim and Akaberian, Sherafat and Hefzollah, Ali}, title = {Comparative Study of Calcium efficacy and placebo on leg muscle cramps during pregnancy in patients referred to clinics supervised by Bushehr University of Medical Sciences}, abstract ={Background: Muscle cramps are common complains during pregnancy muscle cramps occur mostly during nights causing sleep disorder. The causes of muscle cramps are unknown. One probable cause could be the imbalance between intake and excretion of serum electrolyte such as calcium. Methods: The method used for the present study was double blind clinical trial. The study was conducted on 60 pregnant women suffering from leg muscle cramps who sought medical treatment in three selected clinics in Bushehr from April 2006 to November 2007. All subjects being third trimester of pregnancy, single pregnant, only used iron and multivitamins. Irregular use of medication, PLP (Preterm Labor Pain), disability completion forms excluded of study. Simple and accessible sampling was used in this study. Selection of study group and placebo were random. Visual analog forms were used to record the number and intensity of muscle cramps. These forms had provisions for 7 days of pretreatment and 28 days of treatments. At the end of the first week, the subjects were prescribed to take medications every night for four weeks. The subjects were asked to record the intensity of their muscle cramps on the visual analog forms during these four weeks. Results: The number and intensity of muscle cramps were considered in this study. The results of the study showed no significant change in intensity in the two groups. However, there was a significant reduction in the number of cramps in the study group after taking calcium (p=< 0.02<0.05). Conclusion: Taking calcium resulted in a significant reduction in the number of cramps in this study compared to placebo group. Therefore, prescribing calcium is effective in reducing the number of cramps, when the numbers of occurrences are excessive. In cases of highly intensive and painful cramps, however, taking calcium is as effective as placebo.}, Keywords = {pregnancy, muscle cramps, calcium, nocturnal }, volume = {14}, Number = {3}, pages = {185-192}, publisher = {Bushehr University of Medical Sciences}, url = {http://ismj.bpums.ac.ir/article-1-273-en.html}, eprint = {http://ismj.bpums.ac.ir/article-1-273-en.pdf}, journal = {Iranian South Medical Journal}, issn = {1735-4374}, eissn = {1735-6954}, year = {2011} } @article{ author = {Nafisi, Shahryar and Yadegary, Samira and Salimipour, Hooman and Naieni, Rozit}, title = {Review of Brown-Vialetto-Van Laere syndrome and differential diagnosis}, abstract ={Background: Brown-Vialetto-Van Laere syndrome is a neurological devastating condition classified as one of motor neuron disorders. In spite of rarity, it has a widespread distribution. It mostly presented with progressive pontobulbar palsy and bilateral deafness. Diagnosis is based on clinical and electrophysiological findings. Methods: We reviewed related articles by search in pub med, Ovid, Cochrane library and Scopus database. The used key words included motor neuron disorders, Brown-Vialetto-Van laere Syndrome, progressive pontobulbar palsy and sensorineural deafness. Results: The search culminated in 351 articles which 25 were correlated with the subject of our study. The results are presented in epidemiology, pathogenesis, clinical features, diagnosis and differential diagnosis subtitles. Conclusion: In this study Brown-Vialetto-Van Laere syndrome is explained regarding laboratory and clinical findings in previously reported cases. Similar syndromes based on discriminating features were also described.}, Keywords = {motor neuron disorder, Brown-Vialetto-Van laere syndrome, progressive pontobulbar palsy, sensorneural deafness}, volume = {14}, Number = {3}, pages = {193-198}, publisher = {Bushehr University of Medical Sciences}, url = {http://ismj.bpums.ac.ir/article-1-274-en.html}, eprint = {http://ismj.bpums.ac.ir/article-1-274-en.pdf}, journal = {Iranian South Medical Journal}, issn = {1735-4374}, eissn = {1735-6954}, year = {2011} } @article{ author = {Anvarypour, Abdolrasoul and Saffarian, Arash and Alizadehotaghour, Hamidreza and Naseri, Vafa and Ramezanian, Nader}, title = {Awake endotracheal intubation and self positioning the patient to prone position for lumbar discectomy operation}, abstract ={Awake endotracheal intubation is indicated when risk of pulmonary aspiration and difficult airway management is present. In this way, patient cooperation and topical anesthesia with experience of anesthesiologist in difficult airway management is necessary. In this case report, we present a 21-year-old man with (Body Mass Index) = 51 and 140 kg of weight candidates for lumbar discectomy in prone position. After conclusion about his condition with difficult anesthesia, awaked endotracheal intubation in supine position was done and self positioned to prone for operation.}, Keywords = {awaked endotracheal intubation, prone position, lumbar discectomy, morbid obesity}, volume = {14}, Number = {3}, pages = {199-202}, publisher = {Bushehr University of Medical Sciences}, url = {http://ismj.bpums.ac.ir/article-1-275-en.html}, eprint = {http://ismj.bpums.ac.ir/article-1-275-en.pdf}, journal = {Iranian South Medical Journal}, issn = {1735-4374}, eissn = {1735-6954}, year = {2011} } @article{ author = {Nabipour, Iraj}, title = {Technology Foresight: A Tool for sustainability}, abstract ={Our age is one of very rapid progress in the sciences and technologies, together with Globalization. Thus, interrelationships between science, technology and society are becoming more complex. This makes economic and social trends more difficult to predict and hence, more sophisticated approaches are needed to predict new challenges in science and technology. Technology foresight is the most attractive approach. In fact, technology foresight is a “… a systematic means of assessing those scientific and technological developments which could have a strong impact on industrial competitiveness, wealth creation and quality of life. This book presents a brief review or foresighting theory and methods. The book provides a series of key methodologies along with a discussion of how technology foresight relates to sustainability.}, Keywords = {No Keyword}, volume = {14}, Number = {3}, pages = {203-203}, publisher = {Bushehr University of Medical Sciences}, url = {http://ismj.bpums.ac.ir/article-1-276-en.html}, eprint = {http://ismj.bpums.ac.ir/article-1-276-en.pdf}, journal = {Iranian South Medical Journal}, issn = {1735-4374}, eissn = {1735-6954}, year = {2011} } @article{ author = {Shirzad, Hedayatollah and Dehghanian, Seyedeh Leila and Yousefi, Maryam and Nikookar, Morteza and Rafieian, Mahmou}, title = {Effects of tramadol on activity of peritoneal phagocytes in Balb / C mice}, abstract ={Background: Morphine would impair the immune system which particularly in patients with pain or stress might deteriorate the disease process. The aim of this study was to evaluate the effect of tramadol on phagocytic activity of mouse peritoneal phagocytes. Methods: Seventy Balb/c mice were selected and divided into two equal control and treatment groups. The mice in treatment group were received 20, 40, 60, 80 and 100 mg/kg tramadol twice daily from day 1 to 5 respectively and 100 mg/kg from day 6 to 30 once daily. The mice in control group received normal saline. Six mice were euthanized at days 3, 5, 10, 20 and 30 from each group and the samples were obtained from peritoneal cavity. The rate and intensity of phagocytosis were measured by evaluation of sheep red blood cells phagocytosis by phagocytes in peritoneal samples. Results: There was not any significant difference between the two groups in the rate and intensity of phagocytosis during the first five days of the study, although they increased in both groups up to day 10. Thereafter, they increased only in treatment group. The rate of phagocytosis in the first to third samples were 20  4, 23 8, 498 in treatment group and 189, 1911, 321 in control group, respectively. This activity was significantly different in the third sample. Evaluation of sheep red blood cells phagocytosis by phagocytes in peritoneal samples. Phagocytosis intensity in treatment group was higher than control group throughout the study. Conclusion: The results indicate that tramadol can enhance the activity of immune system and in cases that suppose to have immune deficiency, tramadol can be the preferred analgesic.}, Keywords = {phagocytosis, Tramadol, phagocytic cell, immune system}, volume = {14}, Number = {4}, pages = {214-219}, publisher = {Bushehr University of Medical Sciences}, url = {http://ismj.bpums.ac.ir/article-1-299-en.html}, eprint = {http://ismj.bpums.ac.ir/article-1-299-en.pdf}, journal = {Iranian South Medical Journal}, issn = {1735-4374}, eissn = {1735-6954}, year = {2011} } @article{ author = {SaffariChaleshtary, Javad and Moradi, Mohammad taghi and Farrokhi, Effat and Tabatabaiefar, Mohammad Amin and taherzadeh, Maryam and Azadegan, Fatemeh and Mobini, Gholamreza and Banitalebi, Mehdi and Rahimian, Ghorban Ali and HashemzadehChaleshtary, Mortez}, title = {Study of P53 gene mutations in promoter and exons 2-4 and 9-11 in patient with gastric cancer by PCR-SSCP in Chaharmahal Va Bakhtiari province}, abstract ={Background: Gastric cancer is one of the most important diseases and after lung cancer, is the second cause of cancer death worldwide. Genetic factors including oncogenes and tumor suppressor genes are always contributed in progression of this cancer. The P53 tumor suppressor gene has a broad role in genomic stability and DNA repair. The aim of this study was to determine the P53 gene mutations in gastric cancer specimens in Chaharmahal Va Bakhtiari Province. Methods: In this descriptive-lab based study, we investigated the promoter, exons 2-4 and 9-11 of P53 gene mutations in 38 paraffin embedded gastric cancer specimens. DNA was extracted following the standard phenol chloroform protocol. The P53 gene mutations were determined using PCR-SSCP procedure. Results: Our study revealed no P53 gene mutation in promoter and exons 2-4 and 9-11 in the gastric cancer subjects studied. Conclusion: While P53 gene mutations have been reported as the most frequent genetic alterations and are found in about 50% of the human malignancies, no mutation was detected in this study. The reason may be due to small sample size or mutations on other genes or epigenetic factors.}, Keywords = {gastric cancer, mutation, P53 gene, promoter, PCR- SSCP}, volume = {14}, Number = {4}, pages = {220-229}, publisher = {Bushehr University of Medical Sciences}, url = {http://ismj.bpums.ac.ir/article-1-300-en.html}, eprint = {http://ismj.bpums.ac.ir/article-1-300-en.pdf}, journal = {Iranian South Medical Journal}, issn = {1735-4374}, eissn = {1735-6954}, year = {2011} } @article{ author = {Mirzaei, Ali and Mirzaei, Noushin and Mirzaei, Mahsa and Delaviz, hamdollah}, title = {Hepatoprotectivitve effect of Iranian grape seed and Jaft (a part of oak fruit) extracts against CCL4 induced-liver toxicity in rats}, abstract ={Background: Specialists are more interest to grape seed oil for antioxidant activity. Flavonoid compounds, particularly proanthocyanidin are mainly responsible for antioxidant potential in grape seed oil. In addition, recently the interest in using natural remedies to treat diseases increases the use of herbal drugs.The protective effect of grape seed and Jaft extract (a part of oak fruit) was studied on liver toxicity which induced by carbon tetra chloride (CCl4) in rats. Methods: This study carried out on 28 male wistar rats. Mixture of hydroalchoholic grape seed and Jaft extracts was gavaged (200mg/kg) in two groups of extract control and experiment groups, daily for 7 days. At the same time, in two groups of CCl4(toxic ) and treatment, CCl4 in olive oil solution was injected (1ml/kg i.p) since third day, daily, for 5 days. In control groups, olive oil injected (0.5ml/kg i.p) daily, for 5 days. Results: There was significant (P≤0.05) increase in the hepatic enzyme levels such as Aspartate Transaaminase (AST), Alanine Transaminase (ALT), Alkaline Phosphates (ALP) and Bilirubin in toxic group compare to control group. Treat with extract can reduce elevation of liver enzymes AST, ALT, ALP and bilirubin, that caused by CCl4 toxin. The administered of extract only, did not meaningfully alter the enzyme levels when compared to the control groups. Conclusion: According to damage induced by CCl4 and protective potential of extract, we can recommend that mixture of grape seed and Jaft extract has hepatoprotective effect due to antioxidant components.}, Keywords = {grape seed extract, alkaline phosphates, aspartate transaaminase, alanine transaminase, oak fruit }, volume = {14}, Number = {4}, pages = {230-239}, publisher = {Bushehr University of Medical Sciences}, url = {http://ismj.bpums.ac.ir/article-1-301-en.html}, eprint = {http://ismj.bpums.ac.ir/article-1-301-en.pdf}, journal = {Iranian South Medical Journal}, issn = {1735-4374}, eissn = {1735-6954}, year = {2011} } @article{ author = {Rostami, Parastoo and Hatami, Gisoo and Shirkani, Afshi}, title = {Endocrine complications in patients with major β-thalassemia}, abstract ={Background: Endocrine complications in patients with major &beta; –thalassemia related to iron overload that the most important cause of mortality and morbidity in this patients.This study evaluate prevalence of endocrine complications in major &beta; -thalassemia. Methods: Sixty patients with major &beta;- thalassemia enrolled in this study. Results: We assessed 60 patients, including 27 men and 33 female disorders with major &beta;- thalassemia by age range (10-44 years-old). 26.8% of patients didn’t have any endocrine disorders, 23.5% of patients one disorder and 48.7% have more than two. The most common complications of endocrinewere: hypogonadism (66.7%), short stature (45%), hypoparathyroidism (21.7%), diabet mellitus (18.3%), impaired glucose tolerance (6.7%), overt hypothyroidism (1.65%), subclinical hypothyroidism (1.65%). Conclusion: High prevalence of endocrine complications found in this study may emphasize regular endocrine assessment. In thalassemic patients especially in patients over the age of 10 years old.}, Keywords = {βthalassemia major, hypoparathyroidism, short stature, hypogonadism, hypothyroidism, hypoparathyroidism}, volume = {14}, Number = {4}, pages = {240-245}, publisher = {Bushehr University of Medical Sciences}, url = {http://ismj.bpums.ac.ir/article-1-302-en.html}, eprint = {http://ismj.bpums.ac.ir/article-1-302-en.pdf}, journal = {Iranian South Medical Journal}, issn = {1735-4374}, eissn = {1735-6954}, year = {2011} } @article{ author = {Kargar, Mohammad and Najafi, Akram and Zandi, Keyv}, title = {Prevalence of rotavirus gastroenteritis and circulating genotypes in children hospitalized in Borazjan, during 2008-2009}, abstract ={Background: Human rotaviruses are the major etiological agents of acute viral gastroenteritis in infants and young children worldwide. With the licensure of new rotavirus vaccines, data on the burden of disease and the diversity of rotavirus genotypes circulating are important regarding immunization strategies. The purpose of the present study was to determine the genotypes of VP7 protein rotavirus in hospitalized children in Borazjan. Methods: In this study,375 stool samples from children less than 7 year old with severe diarrhaea hospitalized at 17 Shahrivar hospital in Borazjan, were collected during 2008 to 2009. Group A rotavirus antigen was detected in stool specimens using Enzyme Immunoassay (EIA). Then G-typing of the positive specimens was evaluated by Nested RT-PCR method. Results: Among the collected samples, 24.27% were positive for rotavirus infection. The highest incidence was observed in children aged 12-17 months (6.93%) (p=0.056). The most common prevalence of positive rotavirus was observed in autumn with 54.94% compared to the least prevalence in summer with 2.20% (p=0).The frequency of G1, G4, G9 ,non-typeable genotypes were 51.65%, 2.20 %, 4.40%, 41.76% ,respectively. But, G2, G3, G8, G10 and G12 genotypes weren’t detected. Conclusion: The noticeable frequency of non-typeable genotypes indicates that must be using from another primers for characterization of unusual genotypes. Also because of the high frequency of rotavirus infection, surveillance and expanded program of immunization especially for children less than 2 years is necessary.}, Keywords = {rotavirus, nested RT-PCR, VP7, acute gastroenteritis }, volume = {14}, Number = {4}, pages = {246-255}, publisher = {Bushehr University of Medical Sciences}, url = {http://ismj.bpums.ac.ir/article-1-303-en.html}, eprint = {http://ismj.bpums.ac.ir/article-1-303-en.pdf}, journal = {Iranian South Medical Journal}, issn = {1735-4374}, eissn = {1735-6954}, year = {2011} } @article{ author = {Bagheri, Fariborz and Akbarizadeh, Fatemeh and Hatami, Hamidrez}, title = {The Relationship between Spiritual Intelligence and Happiness on the Nurse Staffs of the Fatemeh Zahra Hospital and Bentolhoda Institute of Boushehr City}, abstract ={Background: Spiritual intelligence defined as the capacity of human understanding for asking ultimate, questions about the meaning of life and relation between us and world we are living in it. It seems employing spiritual intelligence in the life will guide us to achieve happiness and wellbeing in the life. The goal of this survey is to investigate relation between of spiritual intelligence and happiness among nurses of two main hospitals, namely Fatemeh Zahra and Bentolhosa in Bousher. Methods: This is a cross-sectional descriptive and inferential designed study. A total of 125 hospital nurses, who were working in Boushehr, were recruited by convenience sampling. The questionnaires were completed by respondents themselves (self reporting). The questionnaires were combined from three parts. I) Spiritual intelligence questionnaire Naseris four-point Linker-type inventory that made in Allameh of university in Iran. II) Oxford happiness questionnaire. III) Demographic characteristics. Results: The findings showed there were significant relationship between spiritual intelligence variables, self-conscious transcendence (p< 0.001, r=0.288), spiritual experiences (p<0.000, r=0.347), patience (p<0.002, r=0.274), and happiness of nurses. But neither happiness nor spiritual intelligence shows any correlation with demographic characteristic such as age, sex, marital status, education, degree, years of nursing experience, but only the ward were the nurses performing their duties with spiritual intelligence and happiness has significant relationship. Conclusion: Promoting spiritual intelligence of the nurses can help them have more stable happiness.}, Keywords = {spiritual nursing, spiritual intelligence, happiness, religion}, volume = {14}, Number = {4}, pages = {256-263}, publisher = {Bushehr University of Medical Sciences}, url = {http://ismj.bpums.ac.ir/article-1-304-en.html}, eprint = {http://ismj.bpums.ac.ir/article-1-304-en.pdf}, journal = {Iranian South Medical Journal}, issn = {1735-4374}, eissn = {1735-6954}, year = {2011} } @article{ author = {Marjani, Mehdi and Faghihi, hoom}, title = {Radiographic evaluation of using Persian Gulf coral powder effect on bone healing defects in rabbits}, abstract ={Background: &zwj;Considering the fact that research on the marine products and creatures, in particular coral, has started just in the past decade and more attentions are focused on the benefits of this material, it has been decided to utilize the coral native to Persian Gulf as oral powder to heal tibia bone defect in rabbit. Methods: In this experimental study 18 New Zealander rabbits weighing 2.5-3 kg were categorized randomly in 3 groups (control, oral calcium powder and oral coral powder group) of 6 rabbits. For inducing the defect, the first 3rd part of tibial bone was blunt dissected. A whole with the depth of 0.6-0.8 mm and diameter of 4 mm was produced in all 3 groups in the same style. The Calcium group was treated daily with 1150 mg calcium powder, coral group received 1220 mg of coral powder and control group were kept under standard condition. Course of treatment was 2 months and on days 0,10,20,30,40,50,63 the animals were evaluated for healing criteria such as filling the defects, density, external callus formation and intercortical callus. Results: Radiologic parameters indicates that filling defect, density, external and inter cortical callus and absorption for animals receiving coral is better than that of control and calcium group (P<0/05). Conclusion: In conclusion, by oral administration of Persian Gulf coral powder results increasing the rate of bone formation. Finally for human use, these results must be evaluated more in clinical studies.}, Keywords = {Persian Gulf coral, bone healing, inter cortical callus, radiography }, volume = {14}, Number = {4}, pages = {264-273}, publisher = {Bushehr University of Medical Sciences}, url = {http://ismj.bpums.ac.ir/article-1-305-en.html}, eprint = {http://ismj.bpums.ac.ir/article-1-305-en.pdf}, journal = {Iranian South Medical Journal}, issn = {1735-4374}, eissn = {1735-6954}, year = {2011} } @article{ author = {Assadi, Mahsan and Nemati, Reza and Nabipour, Iraj}, title = {The Potential role of marine derived food products on Alzheimer\'s disese and cognitive decline}, abstract ={Background: Alzheimer's disese is the most frequent cause of dementia and is one of important cause of mortality and morbidity in the world. Although, there are different therapeutic options for its treatment , the results of these therapies are disappointing. Omega-3 fatty acids in marine- derived food products, affect on different mechanisms, improve cognitive function, memory.in this study, effect Omega-3 fatty acids in marine- derived food products of cognitive disorders and Alzheimer's are reviewed. Methods: The method employed in this research was a systematic bibiliographic review,in which only the double-blind placebo-controlled studies or the clinically detailed enough open-labeled studies using validated scales were retained. Results: Many studies have shown that Omega-3 fatty acids in marine- derived food products, affect by different mechanisms include decrease inflammation and oxidative stress, synaptogenesis, synaptic plasticity, and neurogenesis promotion in neuroprotection and improvement cognitive function and memory, also omega3 fatty acid could lead to a decrease in risk of Alzheimer's diseas and the other cognitive impairements. Conclusion: However, more and large clinical trials are needed to confirm the beneficial effects of omega 3 fatty acid supplementation on the management of Alzheimer's disease and cognitive decline.}, Keywords = {alzheimer\'s disese, cognitive decline, marine, marine products}, volume = {14}, Number = {4}, pages = {274-287}, publisher = {Bushehr University of Medical Sciences}, url = {http://ismj.bpums.ac.ir/article-1-306-en.html}, eprint = {http://ismj.bpums.ac.ir/article-1-306-en.pdf}, journal = {Iranian South Medical Journal}, issn = {1735-4374}, eissn = {1735-6954}, year = {2011} } @article{ author = {Nabipour, Iraj and Assadi, Maji}, title = {Book review: Use of Stable Iodine in Nuclear Emergencies}, abstract ={Following a radiological or nuclear event, radioactive iodine may be get into the body through respiratory or gastrointestinal systems. In the contaminated cases with radioactive iodine, the radioactive iodine absorbed by the thyroid can injure the gland. Because of the carcinogenic effects of its radiation, there is a significant public health risk in the event of exposure to radioactive iodine. On other hand, due to stable (non-radioactive) iodine acts to block radioactive iodine from being taken into the thyroid gland, it can help protect this gland from injury and following side effects. In this query, potassium iodide (also called KI) is a salt of stable iodine in a medicine form which is recommended to use sine many years ago. With effective planning and the use of stable iodine prophylaxis, accompanied with other protective implementations, this risk is mostly avoidable. This book contains information such as iodine and physiology kinetic , exposure risk to radioactive iodine, how to use stable iodine in this events , complications attributed to stable(non-radioactive) iodine and also at last chapter the final recommendation published by WHO is included.}, Keywords = {none}, volume = {14}, Number = {4}, pages = {288-289}, publisher = {Bushehr University of Medical Sciences}, url = {http://ismj.bpums.ac.ir/article-1-307-en.html}, eprint = {http://ismj.bpums.ac.ir/article-1-307-en.pdf}, journal = {Iranian South Medical Journal}, issn = {1735-4374}, eissn = {1735-6954}, year = {2011} }