Volume 25, Issue 5 (Iranian South Medical Journal 2023)
Iran South Med J 2023, 25(5): 442-453 |
Back to browse issues page
Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
Barazesh A, Bolouki H, Obeidi N, Malekizadeh H, Shadvar N, Fouladvand M A. Evaluation of the Presence of Anti-Toxoplasma Antibodies in Blood Donors’ Presenting to Blood Transfusion Center, Bushehr, Iran. Iran South Med J 2023; 25 (5) :442-453
URL: http://ismj.bpums.ac.ir/article-1-1659-en.html
URL: http://ismj.bpums.ac.ir/article-1-1659-en.html
Afshin Barazesh1 
, Heideh Bolouki1 , Narges Obeidi2 , Hasan Malekizadeh3 , Neda Shadvar1 , Morad Ali Fouladvand * 4
, Heideh Bolouki1 , Narges Obeidi2 , Hasan Malekizadeh3 , Neda Shadvar1 , Morad Ali Fouladvand * 4
1- Department of Microbiology & Parasitology, School of Medicine, Bushehr University of Medical Sciences, Bushehr, Iran
2- Department of Laboratory Sciences, School of Para-medicine, Bushehr University of Medical Sciences, Bushehr, Iran
3- Department of Ophthalmology, School of Medicine, Bushehr University of Medical Sciences, Bushehr, Iran
4- Department of Microbiology & Parasitology, School of Medicine, Bushehr University of Medical Sciences, Bushehr, Iran , mfooladvand39@yahoo.com
2- Department of Laboratory Sciences, School of Para-medicine, Bushehr University of Medical Sciences, Bushehr, Iran
3- Department of Ophthalmology, School of Medicine, Bushehr University of Medical Sciences, Bushehr, Iran
4- Department of Microbiology & Parasitology, School of Medicine, Bushehr University of Medical Sciences, Bushehr, Iran , mfooladvand39@yahoo.com
Abstract: (990 Views)
Background: If blood donors are infected with toxoplasmosis, they often have no obvious clinical symptoms due to a healthy immune system, but the Toxoplasma is still present in their white blood cells. Blood recipients are also often people with various anemia or defective immune systems. Therefore, receiving such blood will increase the risk of infection and acute form of toxoplasmosis. The aim of this study was to evaluate the sero-epidemiology of toxoplasmosis in blood donors presenting to Bushehr Blood Transfusion Organization.
Method and Materials: In this descriptive cross-sectional study, 243 blood donors presenting to Bushehr Blood Transfusion Organization from May 2020 to May 2021 were examined for the presence of anti-Toxoplasma IgG and IgM antibodies using ELISA method. The results along with the questionnaire information were analyzed using SPSS software and Chi-square test.
Results: In this study, 76 (31.3%) and 10 (4.1%) blood donors were positive for anti-Toxoplasma IgG and IgM antibodies, respectively. In five cases, both IgG and IgM antibodies were positive. The results revealed no statistically significant relationship between infection with toxoplasma and some of the variables such as permanent residence, age, history of cat ownership, history consuming unpasteurized milk and vegetable cleaning method.
Conclusion: Considering the relatively significant prevalence of toxoplasmosis among blood donors in Bushehr and given the fact that toxoplasmosis is a life-threatening risk factor in immune-compromised blood recipients, it is recommended that health planners add the toxoplasmosis diagnosis tests to the list of essential screening tests for blood donors.
Method and Materials: In this descriptive cross-sectional study, 243 blood donors presenting to Bushehr Blood Transfusion Organization from May 2020 to May 2021 were examined for the presence of anti-Toxoplasma IgG and IgM antibodies using ELISA method. The results along with the questionnaire information were analyzed using SPSS software and Chi-square test.
Results: In this study, 76 (31.3%) and 10 (4.1%) blood donors were positive for anti-Toxoplasma IgG and IgM antibodies, respectively. In five cases, both IgG and IgM antibodies were positive. The results revealed no statistically significant relationship between infection with toxoplasma and some of the variables such as permanent residence, age, history of cat ownership, history consuming unpasteurized milk and vegetable cleaning method.
Conclusion: Considering the relatively significant prevalence of toxoplasmosis among blood donors in Bushehr and given the fact that toxoplasmosis is a life-threatening risk factor in immune-compromised blood recipients, it is recommended that health planners add the toxoplasmosis diagnosis tests to the list of essential screening tests for blood donors.
Type of Study: Original |
Subject:
Parasitology
Received: 2022/10/13 | Accepted: 2023/01/4 | Published: 2023/02/19
Received: 2022/10/13 | Accepted: 2023/01/4 | Published: 2023/02/19
References
1. Madireddy S, Rivas Chacon ED, Mangat R. Toxoplasmosis. Treasure Island (FL): StatPearls Publishing, 2022. [PubMed]
2. Stopić M, Štajner T, Marković-Denić L, et al. Epidemiology of Toxoplasmosis in SERBIA: A Cross-Sectional Study on Blood Donors. Microorganisms 2022; 10(3): 492. [DOI]
3. Hajimohammadi B, Ahmadian S, Firoozi Z, et al. A Meta-Analysis of the Prevalence of Toxoplasmosis in Livestock and Poultry Worldwide. EcoHealth 2022; 19(1): 55-74. [DOI]
4. Mammari N, Halabi MA, Yaacoub S, et al. Toxoplasma gondii modulates the host cell responses: an overview of apoptosis pathways. Biomed Res Int 2019; 2019: 6152489. [DOI]
5. Khabisi SA, Almasi SZ, Zadeh SL. Seroprevalence and Risk Factors Associated with Toxoplasma gondii Infection in the Population Referred to Rural and Urban Health Care Centers in Zahedan, Primary Referral Level, in Southeastern Iran. J Parasitol Res 2022; 2022: 7311905. [DOI]
6. Hosseini SA, Golchin E, Sharif M, et al. A serological investigation and genotyping of Toxoplasma gondii among Iranian blood donors indicates threat to health of blood recipients. Transfus Apher Sci 2020; 59(3): 102723. [DOI]
7. Saebi E. Textbook of Clinical Parasitology, Protozoal Diseases in Iran. Tehran: Hayyan Co 1998: 247-98. [Article]
8. Raisenan S. Toxoplasmosis transmitted by blood transfusion. Transfusion 1978; 18(3): 329-332. [DOI]
9. Assmar M, Amirkhani A, Piazak N, et al. Toxoplasmose en Iran. Résultats d'une étude séroépidémiologique [Toxoplasmosis in Iran. Results of a seroepidemiological study]. Bull Soc Pathol Exot 1997; 90(1): 19-21. [PubMed]
10. Daryani A, Sarvi S, Aarabi M, et al. Seroprevalence of Toxoplasma gondii in the Iranian general population: a systematic review and meta-analysis. Acta Trop 2014; 137: 185-194. [DOI]
11. Ormazdi H, Sanikhani N, Hadighi R, et al. Investigation of antibodies (IgG and IgM) against Toxoplasma gondii in blood donors referred to Tehran blood transfusion organization by ELISA. Urmia M J 2010; 21(2): 212-216. (Persian) [Article]
12. Abdulmawjood A, Rosa S, Taubert A, et al. Investigation of persistence of infectious Toxoplasma gondii in raw sausages using inhouse developed and validated real time-PCR. Meat Sci 2014; 97(4): 542-547. [DOI]
13. John DT, Petri WA. Examinations of stool specimens. In: Markell EK, editors. Medical parasitology. 9 th ed. Missouri: Saunders, 2006, 1-481. [Article]
14. Krick JA, Remington JS. Toxoplasmosis in the adult—an overview. N Engl J Med 1978; 298(10): 550-553. [DOI]
15. Siegel SE, Lunde MN, Gelderman AH, et al. Transmission of toxoplasmosis by leukocyte transfusion. Blood 1971; 37(4): 388-394. [PubMed]
16. Gholami M, Maghsood AH, Mohammadi A, et al. Seroprevalence of Toxoplasmosis in blood donors of Hamadan transfusion center in 2013. Yafte 2015; 17(2): 113-122. (Persian) [Article]
17. Shaddel M, Mirzaii Dizgah I, Sharif F. The prevalence of toxoplasmosis in Imam Reza Hospital blood bank samples, Tehran, Iran. Transfus Apher Sci 2014; 51(2): 181-183. [DOI]
18. Sarkari B, Shafiei R, Zare M, et al. Seroprevalence and molecular diagnosis of Toxoplasma gondii infection among blood donors in southern Iran. J Infect Dev Ctries 2014; 8(04): 543-547. [DOI]
19. Ferdowsi S, Farsi L, Tajalli SM, et al. Seroprevalence anti-Toxoplasma gondii antibodies and anti-Epstein-barr virus (ebv) antibody among volunteer blood donors referred Gonabad Blood Transfusion Organization. Int J Basic Sci Med 2013; 5(2): 60-69. (Persian) [Article]
20. Mansouri A, Adhami Mojarad MR, Badfar G, et al. Epidemiology of Toxoplasma gondii among blood donors in Iran: A systematic review and meta-analysis. Transfus Apher Sci 2017; 56(3): 404-409. [DOI]
21. Sharif M, Ajami A, Daryani A, et al. Serological survey of toxoplasmosis in women referred to Medical Health Laboratory before marriage, northern Iran, 2003-2004. Int J Mol Med Adv Sci 2006; 2(2): 134-137. [Article]
22. Ajami A, Sharif M, Saffar M, et al. Serological study of Toxoplasmosis in women referred to Medical Health Laboratory before marriage, Mazandaran, 2000. J Mazandaran Univ Med Sci 2001; 11(31): 51-56. [Article]
23. Sharif M, Ziaei H, Daryani A, et al. Seroepidemiological study of toxoplasmosis in intellectual disability children in rehabilitation centers of northern Iran. Res Dev Disabil 2007; 28(3): 219-224. [DOI]
24. Fouladvand M, Barazesh A, Zandi K, et al. Seroepidemiological study of toxoplasmosis in childbearing age women in Bushehr city, south west of Iran in 2009. Afr J Biotechnol 2010; 9(36): 5809-5812. [Article]
25. Motazedian MH, Fouladvand M, Barazesh A. The prevalence of toxoplasmosis in hemodialysis patients in Bushehr, Iran in 2012. J Mazandaran Univ Med Sci 2016; 26(141): 123-130. [Article]
26. Barazesh A, Sarkari B, Mehrabi Sisakht F, et al. Seroprevalence and Molecular Evaluation of Toxoplasmosis in Patients Undergoing Chemotherapy for Malignancies in the Bushehr Province, Southwest Iran. Jundishapur J Microbiol 2016; 9(9): e35410. [DOI]
27. Fouladvand MA, Barazesh A, Naiemi B, et al. Seroepidemiological study of toxoplasmosis in girl students from Persian Gulf University and Bushehr University of Medical Sciences. Iran South Med J 2010; 13(2): 114-122. [Article]
28. Fallah E, Navazesh R, Majidi J, et al. An epidemiological study of toxoplasma infection among high-school girls in Jolfa. J Reprod Infertil 2005; 6(3): 261-269. (Persian) [Article]
29. Kamyabi Z, Atapour M. Investigation of the prevalence of Toxoplasma antibodies in women during marriage consultation in Kerman city. J Kerman Univ Med Sci 1999; 6(3): 127-133. (Persian) [Article]
30. manouchehri naeeni K, keshavarz H, abdizade dehkordi R, et al. Seroprevalence of anti-Toxoplasma antibodies among pregnant women from Chaharmahal and Bakhtyari province using indirect immunoflurescent in 2006-2007. J Shahrekord Univ Med Sci 2007; 8(4): 74-80. [Article]
31. Fouladvand M, Jafari SM. Prevalence of antibodies to Toxoplasma gondii in pregnant women of Bushehr. Iran South Med J 2001; 3(2): 113-116. [Article]
32. Daryani A, Sagha M. Seroepidemiology of toxoplasmosis in women referring to the laboratory of health center in Ardabil for premarital medical examinations. J Ardebil Univ Med Sci 2004; 4(13): 19-25. [Article]
33. Saeidi M, Bakhshandehnosrat S, Ghaemi E, et al. The prevalence of Toxoplasma antibodies in women during marriage consultation in Gorgan. J Gorgan Univ Med Sci 2002; 4(1): 64-71. (Persian) [Article]
Send email to the article author
| Rights and Permissions | |
 |
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |
