Volume 20, Issue 5 (Iranian South Medical Journal 2017)
Iran South Med J 2017, 20(5): 501-518 |
Back to browse issues page
Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
Nabipour I. A Roadmap Draft for the Development of Synthetic Biology in I.R. Iran. Iran South Med J 2017; 20 (5) :501-518
URL: http://ismj.bpums.ac.ir/article-1-902-en.html
URL: http://ismj.bpums.ac.ir/article-1-902-en.html
The Persian Gulf Marine Biotechnology Research Center, The Persian Gulf Biomedical Sciences Research Institute, Bushehr University of Medical Sciences, Bushehr, Iran
Future Studies Group, The Academy of Medical Sciences of the I.R. Iran ,inabipour@gmail.com
Future Studies Group, The Academy of Medical Sciences of the I.R. Iran ,
Abstract: (4522 Views)
Background: According to the Royal Academy of Engineering (2009), “synthetic biology aims to design and engineer biologically-based parts, novel devices, and systems as well as redesigning existing, natural biological systems”. It has been predicted that synthetic biology would be one of twelve destructive and creative technologies in the future and would transform the life, business, and economic world.
Methods: By considering critical infrastructures in biological sciences, biomedical research centers, biotechnological infrastructures, national innovation system, national scientific roadmap and centers for doctoral training in the I.R. Iran and recent experiences for the progress of synthetic biology in different countries, a conceptual framework for the development of synthetic biology in the I.R. Iran was designed.
Results: Five strategies may be considered to develop synthetic biology in the I.R. Iran. 1. The establishment of centers of excellence for research in synthetic biology; 2. Support of multidisciplinary cores for biomedical technologies in universities; 3. Networking and building a national Smart Specialization Platform for synthetic biology; 4. Education and training in synthetic biology to provide the critical national workforce mass; 5. Public engagement with synthetic biology.
Conclusion: Together these five strategies provide an important foundation for the establishment of essential infrastructures and expert workforce for the development of synthetic biology in the I.R. Iran. By conducting a practical roadmap, Iran would be a leading nation in synthetic biology in the west part of Asia in the future.
Methods: By considering critical infrastructures in biological sciences, biomedical research centers, biotechnological infrastructures, national innovation system, national scientific roadmap and centers for doctoral training in the I.R. Iran and recent experiences for the progress of synthetic biology in different countries, a conceptual framework for the development of synthetic biology in the I.R. Iran was designed.
Results: Five strategies may be considered to develop synthetic biology in the I.R. Iran. 1. The establishment of centers of excellence for research in synthetic biology; 2. Support of multidisciplinary cores for biomedical technologies in universities; 3. Networking and building a national Smart Specialization Platform for synthetic biology; 4. Education and training in synthetic biology to provide the critical national workforce mass; 5. Public engagement with synthetic biology.
Conclusion: Together these five strategies provide an important foundation for the establishment of essential infrastructures and expert workforce for the development of synthetic biology in the I.R. Iran. By conducting a practical roadmap, Iran would be a leading nation in synthetic biology in the west part of Asia in the future.
Type of Study: Review |
Subject:
General
Received: 2017/10/4 | Accepted: 2017/11/16 | Published: 2017/12/9
Received: 2017/10/4 | Accepted: 2017/11/16 | Published: 2017/12/9
References
1. Synthetic Biology: scope, applications and implications. 2009. Royal Academy of Engineering. (Accessed 29 Oct 2017 at http://www.raeng.org.uk/publications/reports/synthetic-biology-report).
2. Benner SA, Sismour AM. Synthetic biology. Nat Rev Genet. 2005;6:533-43. [DOI:10.1038/nrg1637]
3. Philosophy of Systems and Synthetic Biology. 2017. Metaphysics Research Lab, Stanford University. (Accessed 29 Oct 2017 at https://plato.stanford.edu/entries/systems-synthetic-biology/.
4. Ding Y, Wu F, Tan C. Synthetic Biology: A Bridge between Artificial and Natural Cells. Life (Basel). 2014; 4(4): 1092-116. [DOI:10.3390/life4041092]
5. Holdrege C. When Engineers Take Hold of Life: Synthetic Biology. 2014. (Accessed 29 Oct 2017 at http://natureinstitute.org/pub/ic/ic32/synbio.pdf).
6. Synthetic Biology: An Introduction. 2011. European Academies Science Advisory Council. (Accessed 29 Oct 2017 at http://www.easac.eu/fileadmin/PDF_s/reports_statements/Synthetic%20Biology%20An%20Introduction%20Feb%202011.pdf).
7. Peccoud J, Isalan M. The PLOS ONE synthetic biology collection: six years and counting. PloS one. 2012;7 (8):e43231. [DOI:10.1371/journal.pone.0043231]
8. Kis Z, Pereira HS, Homma T, et al. Mammalian synthetic biology: emerging medical applications. J R Soc Interface. 2015; 12(106): 1-18. [DOI:10.1098/rsif.2014.1000]
9. Courbet A, Renard E, Molina F. Bringing next-generation diagnostics to the clinic through synthetic biology. EMBO Mol Med. 2016; 8(9): 987-91. [DOI:10.15252/emmm.201606541]
10. May M. Synthetic biology's clinical applications. 2015. (Accessed 29 Oct 2017 at http://www.sciencemag.org/custom-publishing/technology-features/synthetic-biology-s-clinical-applications.
11. Evans A, Ratcliffe E. Rising influence of synthetic biology in regenerative medicine. Engineering Biology. 2017; 1(1): 24-29. [DOI:10.1049/enb.2017.0007]
12. Cachat E, Davies JA. Application of Synthetic Biology to Regenerative Medicine. J Bioeng Biomed Sci. 2011; S2: 003. (Accessed 29 Oct 2017 at https://www.omicsonline.org/application-of-synthetic-biology-to-regenerative-medicine-2155-9538.S2-003.pdf).
13. Think synthetic biology. 2016. Ontario Genomics. (Accessed 29 Oct 2017 at http://www.ontariogenomics.ca/syntheticbiology/Ontario_Synthetic_Biology_Report_2016.pdf).
14. Eight great technologies. 2013. UK Department for Business, Innovation and Skills. www.gov.uk. (Accessed 29 Oct 2017 at https://www.gov.uk/government/speeches/eight-great-technologies).
15. National Bioeconomy Blueprint. 2012. Office of Science and Technology Policy: whitehouse.gov. (Accessed 29 Oct 2017 at https://obamawhitehouse.archives.gov/sites/default/files/microsites/ostp/national_bioeconomy_blueprint_exec_sum_april_2012.pdf).
16. Rejeski D, Fellow G, Center W. Synthetic Biology in the United States: A Brief History of an Emerging Innovation System. 2016. (Accessed 29 Oct 2017 at http://platformvaluenow.org/wp-content/uploads/2017/06/SyntheticBiologyCaseStudy_Rejeski.pdf).
17. Si T, Zhao H. A brief overview of synthetic biology research programs and roadmap studies in the United States. Synth Syst Biotechnol. 2016; 1(4): 258-64. [DOI:10.1016/j.synbio.2016.08.003]
18. Clarke LJ, Kitney RI. Synthetic biology in the UK - An outline of plans and progress. Synth Syst Biotechnol. 2016; 1(4): 243-57. [DOI:10.1016/j.synbio.2016.09.003]
19. Next steps for European synthetic biology: a strategic vision from ERASynBio. 2014. (Accessed 29 Oct 2017 at http://www.evolva.com/wp-content/uploads/2016/01/EU-Synbio-Vision.pdf.
20. Workshop on Synthetic Biology. 2015. European Commission. (Accessed 29 Oct 2017 at https://ec.europa.eu/health/sites/health/files/scientific_committees/emerging/docs/ev_20151210_booklet_en.pdf).
21. Singh V, Jain R, Dhar PK. Challenges and Opportunities for Synthetic Biology in India. Curr Synthetic Sys Biol. 2014; 2(3): e112.
22. Singh D, Dhar PK. Exploring the Future of Synthetic Biology in India and its Probable Pathways from Infancy to Maturity. Curr Synthetic Sys Biol. 2013; 1(1): 106.
23. Gronvall GK. US Competitiveness in Synthetic Biology. Health Secur. 2015; 13(6): 378-89. [DOI:10.1089/hs.2015.0046]
24. Hayden E. Tech investors bet on synthetic biology. Nature. 2015; 527: 19. (Accessed 29 Oct 2017 at https://www.nature.com/polopoly_fs/1.18715!/menu/main/topColumns/topLeftColumn/pdf/527019a.pdf?origin=ppub). [DOI:10.1038/527019a]
25. Nabipour I, Assadi M. Infrastructures for systems medicine in Iran's health roadmap. Iran South Med J 2014, 17(5): 974-92.
26. Nabipour I, Mosleh A, Assadi M. Role of the future creative universities in the triple helix of science and technology corridors. Iran South Med J 2015, 17(6): 1068-89.
27. Carter SR. Synthetic Biology and the U.S. Biotechnology Regulatory System Challenges and Options. 2014. J. Craig Venter Institute. (Accessed 29 Oct 2017 at http://www.jcvi.org/cms/fileadmin/site/research/projects/synthetic-biology-and-the-us-regulatory-system/full-report.pdf).
Send email to the article author
| Rights and Permissions | |
 |
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |
