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:: Volume 8, Issue 1 (Iranian south medical of journals 2005) ::
Iran South Med J 2005, 8(1): 8-14 Back to browse issues page
Effect of dietary fish oil and corn oil on blood biochemical factors in diabetic Rat
Mehdi Shariati Mr 1, Mohammad Khaksary Haddad Mr, Hamidreza Jafari Mr, Mehran Bahadoran Mr
1- , shariatik @ Yahoo.com
Abstract:   (16819 Views)
Background: The potential role of omega – 3 (ω-3) and omega-6 (ω-6) fatty acids on blood biochemical factors are in interest and controversy. Some experiences showed that omega – 3 (ω-3) and omega-6 (ω-6) fatty acids have a potential effect on triglyceride, LDL-cholesterol, HDL-cholesterol and total cholesterol levels in diabetes mellitus. Methods: Male rats were divided into four groups (one normal group and three diabetic groups). Induction of diabetes was done by streptozotocin [50mg/kg, s.c. (STZ)]. In diabetic groups, one group was Control, received STZ alone, and the other diabetic groups were fed with fish oil or corn oil for 8 weeks after 4 weeks of induction of diabetes. Plasma glucose, total cholesterol, triglyceride, LDL- choleserol and HDL-cholesterol were measured at 4 and 8 weeks after intervention. Results: Fish oil and corn oil diets had an inhibitory effect on increased plasma glucose in diabetic rat by 46.8% and 40.7%, respectively. Diabetic rats in the control group demonstrated increased plasma total cholesterol, triglyceride and LDL-cholesterol levels, but plasma total cholesterol, triglyceride and LDL-cholesterol levels were significantly decreased and HDL-cholesterol level was increased by both diets in interventional groups. Conclusion: Corn oil and fish oil supplementation have a role on plasma glucose and lipid profile in diabetic rats. To understand the functional mechanisms of these diets, further studies remain to be accomplished.
Keywords: fish oil; corn oil; diabetes; fatty acids
Full-Text [PDF 185 kb]   (1482 Downloads)    
Type of Study: Original | Subject: General
Received: 2009/01/14 | Accepted: 2009/01/14 | Published: 2009/01/14
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Shariati M, Khaksary Haddad M, Jafari H, Bahadoran M. Effect of dietary fish oil and corn oil on blood biochemical factors in diabetic Rat. Iran South Med J. 2005; 8 (1) :8-14
URL: http://ismj.bpums.ac.ir/article-1-53-en.html


Volume 8, Issue 1 (Iranian south medical of journals 2005) Back to browse issues page
دانشگاه علوم پزشکی بوشهر، طب جنوب ISMJ

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