:: Volume 13, Issue 2 (Iranian South Medical Journal 2010) ::
Iran South Med J 2010, 13(2): 93-101 Back to browse issues page
The Correlation of Calcium Intake with Bone Mass Density and Bone Turn Over Markers in Adults in Bushehr Province
Alireza Rahbar Mr 1, Iraj Nabipour Mr
1- , rahbar_alireza@yahoo.com
Abstract:   (14277 Views)
Background: Introduction: Low bone mineral density (BMD) is a major risk factor for osteoporotic fracture. There are emerging evidences, that micronutrients and macronutrients may play a protective role against age related bone loses. In this study the relationship between dietary calcium intake and bone mineral density in adult population was investigated. Methods: A total of 1028 healthy men and women, aged 20-72 years, were randomly selected from 13 clusters in Bushehr port. Dietary calcium intake with a validated FFQ was evaluated. Dual-energy X-ray absorptiometry (DXA) was used to determine the bone mineral density (BMD) of the lumbar spine (L2-L4), distal third of radius, and proximal femur. Serum degradation products of the C-terminal telopeptides of type I collagen (CTX), and osteocalcin were measured by highly specific ELISA methods. Results: There was significant positive age- adjusted linear correlation between dietary calcium intake and femur neck BMD (r=0.06, p<0.05), femur ward’s triangle BMD (r=0.07, p=0.01), and femur trocanter BMD (r=0.06, p<0.05). Negative age-adjusted linear correlation between dietary calcium intake and osteocalcin (r=-0.07, p<0.05) in adults population were significant. Conclusion: It is concluded that a high dietary calcium intake has protective role against osteoprotc fracture and is supported by reduction of osteocalcin, a turn over marker in people who had used more calcium.
Keywords: dietary calcium intake, bone mineral density, C-terminal telopeptides of type I collagen, bone turnover markers, osteocalcin
Full-Text [PDF 179 kb]   (1592 Downloads)    
Type of Study: Original | Subject: General
Received: 2010/05/8 | Accepted: 2010/05/8 | Published: 2010/05/8


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Volume 13, Issue 2 (Iranian South Medical Journal 2010) Back to browse issues page