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The Correlation of Calcium Intake with Bone Mass Density and Bone Turn Over Markers in Adults in Bushehr Province
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| Alireza Rahbar 1, Iraj Nabipour |
| 1- , rahbar_alireza@yahoo.com |
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Abstract: (15544 Views) |
| Background: Introduction: Low bone mineral density (BMD) is a major risk factor for osteoporotic fracture. There are emerging evidences, that micronutrients and macronutrients may play a protective role against age related bone loses. In this study the relationship between dietary calcium intake and bone mineral density in adult population was investigated. Methods: A total of 1028 healthy men and women, aged 20-72 years, were randomly selected from 13 clusters in Bushehr port. Dietary calcium intake with a validated FFQ was evaluated. Dual-energy X-ray absorptiometry (DXA) was used to determine the bone mineral density (BMD) of the lumbar spine (L2-L4), distal third of radius, and proximal femur. Serum degradation products of the C-terminal telopeptides of type I collagen (CTX), and osteocalcin were measured by highly specific ELISA methods. Results: There was significant positive age- adjusted linear correlation between dietary calcium intake and femur neck BMD (r=0.06, p<0.05), femur ward’s triangle BMD (r=0.07, p=0.01), and femur trocanter BMD (r=0.06, p<0.05). Negative age-adjusted linear correlation between dietary calcium intake and osteocalcin (r=-0.07, p<0.05) in adults population were significant. Conclusion: It is concluded that a high dietary calcium intake has protective role against osteoprotc fracture and is supported by reduction of osteocalcin, a turn over marker in people who had used more calcium. |
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| Keywords: dietary calcium intake, bone mineral density, C-terminal telopeptides of type I collagen, bone turnover markers, osteocalcin |
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Full-Text [PDF 179 kb]
(1850 Downloads)
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Type of Study: Original |
Subject:
General
Received: 2009/08/11 | Accepted: 2010/01/23 | Published: 2010/05/8
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