Volume 29, Issue 4 (Iran South Med J 2026)
Iran South Med J 2026, 29(4): 207-219 |
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Taherahmadi H, Khamenehpour K, Razzaghi A, Shirmohammadi S. Investigation of Factors Affecting Sleep Disorders in Infants Less Than One Year of Age with Gastroesophageal Reflux Disease Referred to the Qazvin Sleep Clinic in 2024-2025. Iran South Med J 2026; 29 (4) :207-219
URL: http://ismj.bpums.ac.ir/article-1-2643-en.html
URL: http://ismj.bpums.ac.ir/article-1-2643-en.html
1- Department of Pediatrics, Arak University of Medical Sciences, Arak, Iran
2- Clinical Research Development Unit of Advanced Medicine, Qazvin University of Medical Sciences, Qazvin, Iran ,kh.khamenehpour@qums.ac.ir
3- Social Determinants of Health Research Center, Research Institute for Prevention of Non-Communicable Diseases, Qazvin University of Medical Sciences, Qazvin, Iran
4- Clinical Research Development Unit of Advanced Medicine, Qazvin University of Medical Sciences, Qazvin, Iran
2- Clinical Research Development Unit of Advanced Medicine, Qazvin University of Medical Sciences, Qazvin, Iran ,
3- Social Determinants of Health Research Center, Research Institute for Prevention of Non-Communicable Diseases, Qazvin University of Medical Sciences, Qazvin, Iran
4- Clinical Research Development Unit of Advanced Medicine, Qazvin University of Medical Sciences, Qazvin, Iran
Abstract: (21 Views)
Background: Sleep disorders in infants significantly affect their physical and mental development. Since gastroesophageal reflux disease (GERD) is known to affect sleep quality, this study aimed to investigate the factors associated with sleep disorders in infants with GERD.
Materials and Methods: This descriptive-analytical cross-sectional study was conducted between 2024 and 2025 on infants under 12 months old diagnosed with GERD. Data were collected using a demographic information questionnaire and Infant Sleep Questionnaire (ISQ). Statistical analysis included descriptive statistics, chi-square tests, independent t-tests, and linear regression analysis using SPSS (version 27). A p-value of <0.05 was considered statistically significant.
Results: A total of 261 infants were screened and GERD was diagnosed in 75 (28.73%). Of the 75 infants, 54 (72%) had sleep disturbances (mean infant nighttime sleep duration: 7.9 ± 1.9 hours). Fourteen (25.9%, n=54) breastfed infants and forty (74.1%, n=54) formula-fed infants had sleep disturbances (p=0.008). Infants with GERD who had sleep disturbances had lower mean infant sleep score (45.9 ± 18.3, p < 0.001), parental perception of infant sleep (51.4 ± 21.4, p=0.004), and total sleep questionnaire score (53.13 ± 0.7, p < 0.001).
Conclusion: Sleep disturbances were observed in half of the infants with GERD. Type of feeding, mean sleep score, parental perception of sleep, and total score of the sleep questionnaire were significantly associated with the occurrence of sleep disorders in infants with GERD.
Materials and Methods: This descriptive-analytical cross-sectional study was conducted between 2024 and 2025 on infants under 12 months old diagnosed with GERD. Data were collected using a demographic information questionnaire and Infant Sleep Questionnaire (ISQ). Statistical analysis included descriptive statistics, chi-square tests, independent t-tests, and linear regression analysis using SPSS (version 27). A p-value of <0.05 was considered statistically significant.
Results: A total of 261 infants were screened and GERD was diagnosed in 75 (28.73%). Of the 75 infants, 54 (72%) had sleep disturbances (mean infant nighttime sleep duration: 7.9 ± 1.9 hours). Fourteen (25.9%, n=54) breastfed infants and forty (74.1%, n=54) formula-fed infants had sleep disturbances (p=0.008). Infants with GERD who had sleep disturbances had lower mean infant sleep score (45.9 ± 18.3, p < 0.001), parental perception of infant sleep (51.4 ± 21.4, p=0.004), and total sleep questionnaire score (53.13 ± 0.7, p < 0.001).
Conclusion: Sleep disturbances were observed in half of the infants with GERD. Type of feeding, mean sleep score, parental perception of sleep, and total score of the sleep questionnaire were significantly associated with the occurrence of sleep disorders in infants with GERD.
Original: Original |
Subject:
infants
Received: 2026/05/6 | Accepted: 2026/08/2 | Published: 2026/09/26
Received: 2026/05/6 | Accepted: 2026/08/2 | Published: 2026/09/26
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