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:: Volume 14, Issue 4 (Iranian South Medical Journal 2011) ::
Iran South Med J 2011, 14(4): 240-245 Back to browse issues page
Endocrine complications in patients with major β-thalassemia
Parastoo Rostami 1, Gisoo Hatami2, Afshin Shirkani2
1- school of Medicine, Bushehr University of Medical Sciencse, Bushehr, IRAN , drp_rostami@yahoo.com
2- school of Medicine, Bushehr University of Medical Sciencse, Bushehr, IRAN
Abstract:   (12958 Views)

Background: Endocrine complications in patients with major β –thalassemia related to iron overload that the most important cause of mortality and morbidity in this patients.This study evaluate prevalence of endocrine complications in major β -thalassemia. Methods: Sixty patients with major β- thalassemia enrolled in this study. Results: We assessed 60 patients, including 27 men and 33 female disorders with major β- thalassemia by age range (10-44 years-old). 26.8% of patients didn’t have any endocrine disorders, 23.5% of patients one disorder and 48.7% have more than two. The most common complications of endocrinewere: hypogonadism (66.7%), short stature (45%), hypoparathyroidism (21.7%), diabet mellitus (18.3%), impaired glucose tolerance (6.7%), overt hypothyroidism (1.65%), subclinical hypothyroidism (1.65%). Conclusion: High prevalence of endocrine complications found in this study may emphasize regular endocrine assessment. In thalassemic patients especially in patients over the age of 10 years old.

Keywords: βthalassemia major, hypoparathyroidism, short stature, hypogonadism, hypothyroidism, hypoparathyroidism
Full-Text [PDF 171 kb]   (1630 Downloads)    
Type of Study: Original | Subject: General
Received: 2011/11/30 | Accepted: 2011/11/30 | Published: 2011/11/30
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Rostami P, Hatami G, Shirkani A. Endocrine complications in patients with major β-thalassemia. Iran South Med J. 2011; 14 (4) :240-245
URL: http://ismj.bpums.ac.ir/article-1-302-en.html


Volume 14, Issue 4 (Iranian South Medical Journal 2011) Back to browse issues page
دانشگاه علوم پزشکی بوشهر، طب جنوب ISMJ

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