Volume 15, Issue 1 (Iranian South Medical of Journal 2012)                   Iran South Med J 2012, 15(1): 25-34 | Back to browse issues page

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Bahmani M, Avijgan M, Gholami Ahangaran M, Rafieian M. The Comparison of the anti Limnatis nilotica effets of albendazole and some of the Iranian medicinal plants . Iran South Med J 2012; 15 (1) :25-34
URL: http://ismj.bpums.ac.ir/article-1-310-en.html
1- Young Researchers Club, Department of Basic Science, Dehloran Branch, Islamic Azad university, Ilam, IRAN , mahmood.bahmani@gmail.com
2- Department of Infectious and Tropical Medicine, Iranian Traditional Medicine Research Center, Isfahan University of Medical Sciences, Isfahan, IRAN
3- Young Researchers Club, Department of Veterinary Medicine, Shahrekord Branch, Islamic Azad University, Shahrekord, IRAN
4- Medicinal Plants Research Center, Shahrekord University of Medical Sciences, Shahrekord, IRAN
Abstract:   (14151 Views)

Background: Aquatic leech invade mucosal membrane and causes anemia. Until now, there is not any commercial effective drug for controlling of this parasite. In this experimental study, investigated the effect of some chemical and herbal drugs against leech (Limnatis nilotica). Methods: Methanolic extract of Artemisia kermanensis and Artemisia spp and hydroalcoholic extracts of Scrophularia deserti, Quercus brantii and Achillea spp was prepared. . Each drugs was tested in one group with 9 replicates. Each leech preserve in one separated jar and drugs were added to each jar. Albendazole used as commercial anti-parasite and distilled water was used as negative control. The movement and respond of each Leech was recorded for 720 minutes. Also, the leeches were monitored for paralysis and death in this duration. Results: In this study, leeches receiving albendazol (600mg) died at 138 min after exposure with albendazol. But exposure with methanolic extracts of Artemisia kermanensis (600 mg), Artemisia spp (600 mg) and hydroalcoholic extracts of Quercus brantii (600 mg), Achillea spp (600 mg) and Scrophularia deserti (600 mg) have no effect on liviability of leeches. Methanolic extract of Artemisia kermanensis with doses of 1800 and 2400 mg, caused death in leeches after 720, 635 and 188 minutes, respectively. Also, methanolic extracts of Arthemisia spp with doses of 1200, 1800 and 2400 mg, caused death in leeches after 720 , 600 and 601 minutes, respectively. Conclusion: This study demonstrated that the herbal drugs that used in this study with compare to albendazole have no considering effect on Limniatis nilotica.

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Type of Study: Original | Subject: General
Received: 2010/06/30 | Accepted: 2010/09/28 | Published: 2012/01/16

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