[Home ] [Archive]   [ فارسی ]  
:: Main :: About :: Current Issue :: Archive :: Search :: Submit :: Contact ::
:: Volume 23, Issue 4 (Iranian South Medical Journal 2020) ::
Iran South Med J 2020, 23(4): 321-329 Back to browse issues page
Developmental Skills of Children with and Without Congenital Hypothyroidism
Belghes Rovshan1 , Afagh Hassanzadeh Rad 2, Satila Dalili3, Ali Reza Gholi Famian1
1- Department of Linguistics and Foreign Languages, School of Persian Literature and Foreign Languages, Payame Noor University, Tehran, Iran
2- Department of Linguistics and Foreign Languages, School of Persian Literature and Foreign Languages, Payame Noor University, Tehran, Iran , afaghrad@yahoo.com
3- Pediatric Diseases Research Center, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran
Abstract:   (601 Views)
Background: Congenital hypothyroidism is one of the most common endocrinology diseases in children. Given the importance of evaluating the normal growth and development and identifying growth and
development abnormalities, this study aimed to evaluate the developmental skills of patients with congenital hypothyroidism and healthy children.
Materials and Methods: This controlled cross-sectional study recruited 30 children with congenital hypothyroidism and 30 healthy children aged three to five years who presented to endocrine clinic of 17 Shahrivar Hospital in Rasht. Ages and Stages Questionnaire, with 5 developmental domains of communication, gross motor skills, fine motor skills, problem solving, and personal-social skills was completed.
Results: Comparison of the two groups revealed no significant difference between the groups in the domains of gross motor, problem solving, and personal-social skills (P>0.05), while there was a significant
difference between them in the domains of communication and fine motor skills (P<0.05). Although lower mean scores of all skills were noted in patients with congenital hypothyroidism, the scores were acceptable.
Conclusion: Based on the results, it appears that addressing congenital hypothyroidism and its
complications can affect children’s health.
 
Keywords: Congenital Hypothyroidism, Developmental Skills, Growth Skills, Growth disorders
Full-Text [PDF 390 kb]   (131 Downloads)    
Type of Study: Original | Subject: Endocrine System
Received: 2020/03/4 | Accepted: 2020/06/16 | Published: 2020/09/30
References
1. Dalili S, Rezvani SM, Dalili H, et al. Congenital Hypothyroidism: Etiology And Growth-Development Outcome. Acta Med Iran 2014; 52(10): 752-6.
2. Karamizadeh Z, Dalili S, Sanei-Far H, et al. Does Congenital Hypothyroidism Have Different Etiologies In Iran?. Iran J Pediatr 2011; 21(2): 188-92.
3. Nabipour I, Rezapour F, Jafary SM. Evaluating autoimmunity markers (TPO Ab, Tg Ab and TM Ab) in hypothyroid patients of Bushehr province . Iran South Med J 2005; 8(1): 37-42.
4. Kooistra L, Vulsma T, Van Der Meere J. An Investigation Of Impulsivity In Children With Early-Treated Congenital Hypothyroidism. Dev Neuropsychol 2004; 26(2): 595-610. [DOI:10.1207/s15326942dn2602_4]
5. Mehran L, Khalili D, Yarahmadi S, et al. Evaluation Of The Congenital Hypothyroidism Screening Programme In Iran: A 3-Year Retrospective Cohort Study. Arch Dis Child Fetal Neonatal Ed 2019; 104(2): F176-81. [DOI:10.1136/archdischild-2017-313720]
6. Baridkazemi S, Bahrami HR, Eftekhari Gol R, et al. Investigation Of The Risk Factors For Congenital Hypothyroidism In Iran: A Population-Based Case-Control Study. Int J Pediatr 2019; 7(2): 8951-8.
7. Wheeler SM, Willoughby KA, Mcandrews MP, et al. Hippocampal Size And Memory Functioning In Children And Adolescents With Congenital Hypothyroidism. J Clin Endocrinol Metab 2011; 96(9): E1427-34. [DOI:10.1210/jc.2011-0119]
8. Redmond GP. Hypothyroidism And Women's Health. Int J Fertil Womens Med 2002; 47(3): 123-7.
9. Dalili S, Rezvany SM, Dadashi A, et al. Congenital Hypothyroidism: A Review Of The Risk Factors. Acta Med Iran 2012; 50(11): 735-9.
10. Sajedi F, Vameghi R, Kraskian Mojembari A, et al. Standardization And Validation Of The ASQ Developmental Disorders Screening Tool In Children Of Tehran City. Tehran Univ Med J 2012; 70(7): 436-46. (Persian)
11. Zeinalzadeh AH, Alizadeh M, Dadashzadeh H, et al. Comparison Of Anthropometric Indices In Children With Congenital Hypothyroidism Detected By Screening, With Healthy Children In School Age. Stud Med Sci 2015; 26(3): 237-42. (Persian)
12. Feizi A, Hashemipour M, Hovsepian S, et al. Study Of The Efficacy Of Therapeutic Interventions In Growth Normalization Of Children With Congenital Hypothyroidism Detected By Neonatal Screening. Iran J Endocrinol Metab 2011; 13(6): 681-9. (Persian)
13. Ng SM, Wong SC, Didi M. Head Circumference And Linear Growth During The First 3 Years In Treated Congenital Hypothyroidism In Relation To Aetiology And Initial Biochemical Severity. Clin Endocrinol 2004; 61(1): 155-9. [DOI:10.1111/j.1365-2265.2004.02087.x]
14. Soliman AT, Azzam S, Elawwa A, et al. Linear Growth And Neurodevelopmental Outcome Of Children With Congenital Hypothyroidism Detected By Neonatal Screening: A Controlled Study. Indian J Endocrinol Metab 2012; 16(4): 565-8. [DOI:10.4103/2230-8210.98012]
15. Khabiri SR, Namakin K, Pordanjani SR. A Comparison Of Healthy Children And Children Of Patients With Congenital Hypothyroidism Treated Under Treatment With Some Evolutionary Indicators. J Birjand Univ Med Sci 2017; 24(3): 199-206. (Persian)
16. Komur M, Ozen S, Okuyaz C, et al. Neurodevelopment Evaluation In Children With Congenital Hypothyroidism By Bayley-III. Brain Dev 2013; 35(5): 392-7. [DOI:10.1016/j.braindev.2012.07.003]
17. Rovet JF, Ehrlich R. Psychoeducational Outcome In Children With Early-Treated Congenital Hypothyroidism. Pediatrics 2000; 105(3): 515-22. [DOI:10.1542/peds.105.3.515]
18. Huo K, Zhang Z, Zhao D, et al. Risk Factors For Neurodevelopmental Deficts In Congenital Hypothyroidism After Early Substitution Treatment. Endocr J 2011; 58(5): 355-61. [DOI:10.1507/endocrj.K10E-384]
Send email to the article author

Add your comments about this article
Your username or Email:

CAPTCHA


XML   Persian Abstract   Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Rovshan B, Hassanzadeh Rad A, Dalili S, Gholi Famian A R. Developmental Skills of Children with and Without Congenital Hypothyroidism. Iran South Med J. 2020; 23 (4) :321-329
URL: http://ismj.bpums.ac.ir/article-1-1331-en.html


Volume 23, Issue 4 (Iranian South Medical Journal 2020) Back to browse issues page
دانشگاه علوم پزشکی بوشهر، طب جنوب ISMJ

Iranian South Medical Journal is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License which allows users to read,
copy, distribute and make derivative works for non-commercial purposes from the material, as long as the author of the original work is cited properly

Copyright © 2017, Iranian South Medical Journal| All Rights Reserved

Persian site map - English site map - Created in 0.04 seconds with 30 queries by YEKTAWEB 4313