دوره 24، شماره 4 - ( دو ماهنامه طب جنوب 1400 )                   جلد 24 شماره 4 صفحات 340-300 | برگشت به فهرست نسخه ها


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Mohebbi G H. Stonefish (Synanceja spp.) from A to Z and their Envenomation: a Review. Iran South Med J 2021; 24 (4) :300-340
URL: http://ismj.bpums.ac.ir/article-1-1502-fa.html
محبی غلامحسین. توکسینولوژی سنگ ماهی(Synanceja spp.) ، از الف تا یاء: یک مطالعه مروری. مجله طب جنوب. 1400; 24 (4) :300-340

URL: http://ismj.bpums.ac.ir/article-1-1502-fa.html


مرکز تحقیقات زیست فناوری دریایی‌ خلیج‌فارس، پژوهشکده علوم زیست پزشکی خلیج‌فارس، دانشگاه علوم پزشکی بوشهر، بوشهر، ایران ، mohebbihsn@yahoo.com
چکیده:   (3955 مشاهده)
اعتقاد بر این است که سنگ ماهی، زهرآگینترین، خطرناکترین و حتی کشندهترین ماهی برای انسان و جانوران است که تاکنون در جهان شناخته شده است. دستگاه زهری آنها شامل 13-12 هیپودرمیک پشتی، دو پلیویک و سه خار مقعدی است که حاوی زهر هستند. خارهای سینه­ای تزئینی بوده و زهری نیستند. زهر آنها حاوی مخلوطی از پروتئینهای آنزیمی و غیرآنزیمی نظیر استونوستوکسین، تراکینیلیزین، وروکوتوکسین و نئووروتوکسین با فعالیت­های بیولوژیک و مکانیسمهای سمیت مختلف است. آنها با مکانیسمهای گوناگونی، بر روی گیرندهها و کانالهای یونی عمل میکنند و موجب عوارض برجسته موضعی و سیستمیک در جانوران تلقیح شده با زهر میشوند. بیشتر پروتکلهای معمولی مدیریت مسمومیت شامل احیای اولیه، تسکین علائم درد با آب گرم (45 درجه سانتی­گراد)، کاربرد آنتی ونوم برای رفع علائم موضعی سیستمیک یا شدید و برداشتن تیغها یا دیگر اجسام خارجی با جراحی می­باشند. توصیههای متعددی در مورد استفاده از غوطهوری ارگان مورد تهاجم در آب داغ، به عنوان یک اقدام اولیه وجود دارد. آنتی­بیوتیک­ها در زخم­های عمیق به دلیل شیوع زیاد زخم به همراه، نکروز و عفونت­های ثانویه، پیشنهاد می­گردند. مانند هر چیز دیگری، پیشگیری بهتر از درمان است و باید در آب­های مناطقی که سنگ­ماهی وجود دارند، کفش پوشید و آگاهانه قدم برداشت.
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نوع مطالعه: مروری | موضوع مقاله: داروشناسی
دریافت: 1400/4/14 | پذیرش: 1400/5/18 | انتشار: 1400/8/8

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