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:: Volume 14, Issue 1 (Iranian South Medical of Journal 2011) ::
Iran South Med J 2011, 14(1): 17-22 Back to browse issues page
In vitro Antibacterial Activities of the Marine Macroalgae" Laurencia Snyderiae" and "Sargassum Angustifolium" Against Human Pathogens
Behrouz Derakhshesh 1, Morteza Yousefzadi, Mohammad Afshar nasab, Vahid Yeganeh, Aghil Dashtian Nasab
1- , behruzdrakhshesh@yahoo.com
Abstract:   (21475 Views)
Background: Nowadays widespread applications of antibiotics caused to create resistant microorganisms and increased additive antibiotic resistance in all over the world. Thus, researches linked to investigate new antimicrobial agents that are produced in natural way have great significance to achieve new pharmaceutics resources. Based on many accomplished researches, some macroalgae have found to show noticeable antimicrobial and antifungal activities. Methods: In this research antimicrobial activity of organic extracts of the macroalgae "Laurencia snyderiae" and Sargassum angustifolium (which has been collected from coasts of Boushehr port) was tested against 3 Gram- positive bacteria Streptococous mutans, Streptococous salivaris and Streptococous sanguis as well as 4 Gram- negative bacteria Salmonella typhi, Proteus vulgaris, Shigella flexniu and Micrococos luteus. Extraction was carried out using maceration method, methanol and chloroform extracts was obtained. Antimicrobial activities of the final extracts was tested using two methods agar disk diffusion method and serial tube dilution method (in order to determine) Minimum Inhibitory Concentration (MIC). Results: Results of bioassay showed the tested macroalgae exhibited the highest antibacterial activity against Gram- negative bacteria, S. typhi and Gram- negative bacteria M. Luteus exhibited the highest resistant against algal extracts. Conclusion: red alga L. snyderiae exhibited higher antibacterial activity than brown alga S. angustifolium against tested bacteria strains.
Keywords: laurencia snyderiae, sargassum angustifolium, antibacterial activity, MIC
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Type of Study: Original | Subject: General
Received: 2010/02/18 | Accepted: 2010/06/16 | Published: 2011/01/31
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Derakhshesh B, Yousefzadi M, Afshar nasab M, Yeganeh V, Dashtian Nasab A. In vitro Antibacterial Activities of the Marine Macroalgae" Laurencia Snyderiae" and "Sargassum Angustifolium" Against Human Pathogens. Iran South Med J. 2011; 14 (1) :17-22
URL: http://ismj.bpums.ac.ir/article-1-240-en.html

Volume 14, Issue 1 (Iranian South Medical of Journal 2011) Back to browse issues page
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