1- Department of Pediatrics, School of Medicine, Bushehr University of Medical Sciences, Bushehr, IRAN 2- Department of Obstetrics & Gynecology, School of Medicine, Bushehr University of Medical Sciences, Bushehr, IRAN 3- Department of Community Medicine, School of Medicine, Bushehr University of Medical Sciences, Bushehr, IRAN Persian Gulf Nuclear Medicine Research Center, The Persian Gulf Biomedical Research Center, Busheh University of Medical Sceinecs, Bushehr, IRAN , motamedn@bpums.ac.ir 4- Department of Pathology, School of Medicine, Bushehr University of Medical Sciences, Bushehr, IRAN 5- School of Medicine, Bushehr University of Medical Sciences, Bushehr, IRAN
Abstract: (8933 Views)
Abstract Background: Vitamin D deficiency during pregnancy has important implications for the mother and infant. Adequate vitamin D concentrations during pregnancy are necessary to neonatal calcium homeostasis, bone maturation and mineralization. This study was designed to evaluate serum 25-OH vitamin D concentration in Bushehrian mothers and effect of vitamin D deficiency on pregnancy outcomes. Material and Methods: One hundred full-term pregnant women were recruited from a university hospital in Bushehr port, in spring & summer 2012. Maternal blood samples were collected on the day of delivery. Serum was assayed for 25-hydroxy vitamin D, calcium, phosphors and PTH. Vitamin D concentration of less than 20 ng/ml was considered as hypovitaminosis D. Results: Prevalence of vitamin D Deficiency was 76%. A significant direct correlation was seen between maternal serum calcium and birth weight of neonates (r= -0.31, P= 0.002). Mean serum level of vitamin D in mothers aged less than 30 years was significantly higher in comparison to less than 30 years mothers. (P= 0.24, 95% CI= 0.02-0.32). A significant direct correlation was seen between serum vitamin D level and parathormone (r= -0.33, P= 0.001). Conclusion: Consideration of adequate calcium and vitamin D intake during pregnancy is essential. Furthermore, it seems it is necessary to reconsider recommendation for vitamin D supplementation during pregnancy.
Hatami G, Ahmadi S, Motamed N, Eghbali S S, Amirani S. 25-OH Vitamin D serum level in pregnant women in Bushehr- 2012. Iran South Med J 2014; 16 (6) :410-418 URL: http://ismj.bpums.ac.ir/article-1-472-en.html
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