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:: Volume 6, Issue 1 (Iranian south medical of journals 2003) ::
Iran South Med J 2003, 6(1): 45-52 Back to browse issues page
Efficacy of ibuprofen, naproxen and mefenamic acid for relief of pain from primary dysmenorrheal
Azita Norouzi Ms , Rahim Tahmasevi Mr, Farahnaz Kamali Mrs
Abstract:   (16912 Views)
Cyclic pain associated with menses during ovulatory cycles, but without demonstrable lesions affecting the reproductive cycle, is a common disability, which causes significant absence from school or work. To evaluate the efficacy of naproxen, ibuprofen and mefenamic acid in the treatment of primary dysmenorrheal, 120 girls were randomized to four groups (three as treatment groups and the other as placebo). The pain intensity was recorded using self visual analogue scale in 0, 1, 2, 4 and 6 hours after treatment. There was no significant difference in intensity of pain between groups at zero time, however the pain intensity decreased significantly in all treatment group in comparison to placebo (p<0.05). The mean of pain intensity was lower in ibuprofen in comparison to the other treatment groups, however there was no significant difference in pain intensity between the treatment groups in the sixth hour of treatment. Therefore, ibuprofen is recommended as a treatment choice for pain reduction in primary dysmenorrheal due to its rapid onset of action.
Keywords: primary dysmenorrheal, naproxen, ibuprofen, mefenamic acid
Full-Text [PDF 189 kb]   (1412 Downloads)    
Type of Study: Original | Subject: General
Received: 2009/01/19 | Accepted: 2009/01/19 | Published: 2009/01/19
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Norouzi A, Tahmasevi R, Kamali F. Efficacy of ibuprofen, naproxen and mefenamic acid for relief of pain from primary dysmenorrheal. Iran South Med J. 2003; 6 (1) :45-52
URL: http://ismj.bpums.ac.ir/article-1-108-en.html


Volume 6, Issue 1 (Iranian south medical of journals 2003) Back to browse issues page
دانشگاه علوم پزشکی بوشهر، طب جنوب ISMJ

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