Volume 26, Issue 4 (Iranian South Medical Journal 2024)
Iran South Med J 2024, 26(4): 248-259 |
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Gharepapagh E, Aryanpour F, Fakhari A, Dabiri Oskui S. Prevalence and Intensity of Vesicoureteral Reflux in Children with UTI based on Direct Radionuclide Cystography. Iran South Med J 2024; 26 (4) :248-259
URL: http://ismj.bpums.ac.ir/article-1-1860-en.html
URL: http://ismj.bpums.ac.ir/article-1-1860-en.html
1- Medical Radiation Sciences Research Team, Tabriz University of Medical Sciences, Tabriz, Iran
Department of Nuclear Medicine, School of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran ,esmaeil.gharepapagh@gmail.com, gharepapaghe@tbzmed.ac.ir
2- Medical Radiation Sciences Research Team, Tabriz University of Medical Sciences, Tabriz, Iran
Department of Nuclear Medicine, School of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran
Department of Nuclear Medicine, School of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran ,
2- Medical Radiation Sciences Research Team, Tabriz University of Medical Sciences, Tabriz, Iran
Department of Nuclear Medicine, School of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran
Abstract: (478 Views)
Background: Urinary tract infection (UTI) is considered one of the most common types of infection in children. Vesicoureteral reflux (VUR) is one of the major risk factors of UTI leading to renal scarring. Cur-rently, two diagnostic methods are used for the evaluation of VUR, including voiding cystourethrography (VCUG) and radionuclide cystourethrography (DRNC). The present study examines the prevalence and intensity of VUR using direct radionuclide cystography (DRNC) in children referred to the Nuclear Medi-cine Division of Imam Reza Hospital in Tabriz, Iran.
Materials and Methods: The referred patients were studied by DRNC in filling, post filling, voiding and post voiding phases if there was confirmed VUR or not. Furthermore, VCUG, sonography and urine cul-ture had been performed for all the patients prior to our investigation. Both dynamic and static imaging were performed from the bladder, ureters and kidneys. The results were studied by a nuclear medicine physician to assess VUR and grade it.
Results: The prevalence of VUR among all 300 patients was calculated to be 29.3%. Most of the cases of VUR were unilateral (63.6%), among which involvement of the left kidney (42%) was significantly more frequent (p=0.022). The most common grade in the cases with unilateral involvement was grade B, and in those with bilateral involvement, grade C. The highest frequency of VUR was observed in the age group below 1 year (10%, n=30), followed by 1-4 years and 5-8 years, each with the frequency of 8.67% (n=26). There was no significant difference in terms of frequency of VUR based on age (p=0.198).
Conclusion: Our study showed that there is no significant association between VUR and urine culture results, but there is significant association between sonography/clinical findings and VUR. Moreover, the results demonstrated that DRNC is more sensitive than VCUG in the detection of VUR.
Materials and Methods: The referred patients were studied by DRNC in filling, post filling, voiding and post voiding phases if there was confirmed VUR or not. Furthermore, VCUG, sonography and urine cul-ture had been performed for all the patients prior to our investigation. Both dynamic and static imaging were performed from the bladder, ureters and kidneys. The results were studied by a nuclear medicine physician to assess VUR and grade it.
Results: The prevalence of VUR among all 300 patients was calculated to be 29.3%. Most of the cases of VUR were unilateral (63.6%), among which involvement of the left kidney (42%) was significantly more frequent (p=0.022). The most common grade in the cases with unilateral involvement was grade B, and in those with bilateral involvement, grade C. The highest frequency of VUR was observed in the age group below 1 year (10%, n=30), followed by 1-4 years and 5-8 years, each with the frequency of 8.67% (n=26). There was no significant difference in terms of frequency of VUR based on age (p=0.198).
Conclusion: Our study showed that there is no significant association between VUR and urine culture results, but there is significant association between sonography/clinical findings and VUR. Moreover, the results demonstrated that DRNC is more sensitive than VCUG in the detection of VUR.
Keywords: Urinary tract infection, vesicoureteral reflux, voiding cystourethrography, radionuclide cystourethrography
Type of Study: Original |
Subject:
nuclear medicine
Received: 2023/11/25 | Accepted: 2024/02/6 | Published: 2024/03/3
Received: 2023/11/25 | Accepted: 2024/02/6 | Published: 2024/03/3
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