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A case of Mantle Cell Lymphoma with Multiple Lymphomatous Polyposis
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| Seyed Masoud Tabib1, Mohammadreza Ravanbod, Seyed Mohammad Valizadeh, Mohammadreza Farzaneh |
| 1- , mohamadsalehtabib@yahoo.com |
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Abstract: (13700 Views) |
| Multiple Lymphomatous Polyposis (MLP) is characterized by multiple polyps involving long segments of the GI tract. More than 75% of the cases are derived from pregerminal center B cells (mantle zone B cells) & less than 25% from germinal center B cells. Thus MLP is a heterogenous group that includes Mantle Cell Lymphoma (MCL) & Follicular Lymphoma (FL). Here we present a 75-year-old sailor who referred to us with abdominal pain, bloody diarrhea, iron deficiency anemia & lymphadenopathy in inguinal & femoral regions. The presence of intestinal polyposis in colonoscopic & endoscopic evaluations & the pathologic & immunohistochemical findings on tissue specimens that showed B cell lymphoma with moderate proliferative activity (50%) & nodular proliferation of small lymphocytes accompanied with positivity for CD5, CD20, CD43 & negativity for CD3, CD10, CD23 revealed that these findings are consequent to MCL with accompanied MLP. |
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| Keywords: mantle cell lymphoma, multiple lymphomatous polyposis, none hodgkin’s lymphoma, polyposis |
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Full-Text [PDF 1249 kb]
(1543 Downloads)
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Type of Study: Original |
Subject:
General
Received: 2010/08/1 | Accepted: 2010/09/29 | Published: 2010/11/13
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