Volume 13, Issue 4 (Iranian South Medical of Journal 2010)                   Iran South Med J 2010, 13(4): 293-298 | Back to browse issues page

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Tabib S M, Ravanbod M, Valizadeh S M, Farzaneh M. A case of Mantle Cell Lymphoma with Multiple Lymphomatous Polyposis . Iran South Med J 2010; 13 (4) :293-298
URL: http://ismj.bpums.ac.ir/article-1-235-en.html
1- , mohamadsalehtabib@yahoo.com
Abstract:   (14174 Views)
Multiple Lymphomatous Polyposis (MLP) is characterized by multiple polyps involving long segments of the GI tract. More than 75% of the cases are derived from pregerminal center B cells (mantle zone B cells) & less than 25% from germinal center B cells. Thus MLP is a heterogenous group that includes Mantle Cell Lymphoma (MCL) & Follicular Lymphoma (FL). Here we present a 75-year-old sailor who referred to us with abdominal pain, bloody diarrhea, iron deficiency anemia & lymphadenopathy in inguinal & femoral regions. The presence of intestinal polyposis in colonoscopic & endoscopic evaluations & the pathologic & immunohistochemical findings on tissue specimens that showed B cell lymphoma with moderate proliferative activity (50%) & nodular proliferation of small lymphocytes accompanied with positivity for CD5, CD20, CD43 & negativity for CD3, CD10, CD23 revealed that these findings are consequent to MCL with accompanied MLP.
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Type of Study: Original | Subject: General
Received: 2010/08/1 | Accepted: 2010/09/29 | Published: 2010/11/13

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