Volume 29, Issue 2 (Iran South Med J 2026)                   Iran South Med J 2026, 29(2): 89-101 | Back to browse issues page


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Mohamadi S, Eskandariazad H, Ramezanzadeh M. Risk Factors among Infertile Couples Presenting to Omid Persian Gulf Infertility Treatment Center, Bushehr, in 2021. Iran South Med J 2026; 29 (2) :89-101
URL: http://ismj.bpums.ac.ir/article-1-2546-en.html
1- Department of Community Medicine, School of Medicine, Bushehr University of Medical Sciences, Bushehr, Iran
2- Student Research and Technology Committee, Bushehr University of Medical Sciences, Bushehr, Iran
3- Department of Genetics and Molecular Medicine, School of Medicine, Bushehr University of Medical Sciences, Bushehr, Iran , M.Ramezanzadeh@bpums.ac
Abstract:   (197 Views)
Background: Infertility is one of the most significant reproductive health challenges and is recognized by the World Health Organization as a global concern. Given the lack of comprehensive studies in Bushehr Province, this study aimed to investigate the risk factors among couples presenting to Omid Persian Gulf Infertility Treatment Center.
Materials and Methods: This cross-sectional study was enrolled 134 infertile couples who visited Omid Persian Gulf Infertility Treatment Center in Bushehr in 2021. Convenience sampling was used to select the participants. Data were collected through interviews and review of clinical and laboratory records. Demographic, clinical, and laboratory variables were assessed. Data were analyzed using descriptive statistics including mean, standard deviation, frequency, and percentage in SPSS version 26.
Results: The mean age of infertile women and men was 32.02 ± 6.90 and 36.30 ± 6.47 years, respectively. Among the studied couples, 80 couples (59.7%) had primary infertility and 54 couples (40.3%) had secondary infertility. The cause of infertility was female-related in 54 cases (40.3%), male-related in 19 cases (14.2%), combined in 52 cases (38.8%), and unexplained in 9 cases (6.7%). The most common female cause of infertility was polycystic ovary syndrome, observed in 96 individuals (71.7%). The most common male factor was varicocele, reported in 35 individuals (21.6%). A family history of infertility was present in 27.6% of the participants.
Conclusion: Primary infertility was more prevalent than secondary infertility. The most common male and female causes were varicocele and polycystic ovary syndrome, respectively. These findings provide valuable insights into the pattern of infertility in Bushehr Province and may inform future research priorities as well as the planning and delivery of infertility-related healthcare services.
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Original: Original | Subject: Gynecology
Received: 2024/12/23 | Accepted: 2026/06/29 | Published: 2026/07/29

References
1. Zegers-Hochschild F, Adamson GD, Dyer S, et al. The international glossary on infertility and fertility care, 2017. Fertil Steril 2017; 108(3): 393-406. [DOI]
2. Tabong PT, Adongo PB. Infertility and childlessness: a qualitative study of the experiences of infertile couples in North Ghana. BMC Pregnancy Childbirth 2013; 13: 72. [DOI]
3. Cox CM, Thoma ME, Tchangalova N, et al. Infertility prevalence and the methods of estimation from 1990 to 2021: a systematic review and meta-analysis. Hum Reprod Open 2022; 2022(4): hoac051. [DOI]
4. Taheri Panah R, Haghdoost A.A, Baneshi M.R, et al. Nationwide prevalence of infertility in Iranian couples: findings from a 2019 study. BMC Public Health 2025; 25(1): 1963. [DOI]
5. Aryanpur M, Heydari Gh, Tarahomi M, et al. Prevalence of tobacco smoking among infertile couples in Tehran. J Reprod Infertil 2009; 9(4): 342-349. (Persian) [Article]
6. Sarvari A, Naderi MM, Heidari M, et al. Effect of Environmental Risk Factors on Human Fertility. J Reprod Infertil 2010; 11(4): 211-225. (Persian) [Article]
7. Agarwal A, Mulgund A, Hamada A, et al. A unique view on male infertility around the globe. Reprod Biol Endocrinol 2015; 13: 37. [DOI]
8. Kazemijaliseh H, Tehrani FR, Behboudi-Gandevani S, et al. The prevalence and causes of primary infertility in Iran: a population-based study. Glob J Health Sci 2015; 7(6): 226-232. [DOI]
9. Masoumi S Z, Parsa P, Darvish N, et al. An epidemiologic survey on the causes of infertility in patients referred to infertility center in Fatemieh Hospital in Hamadan. Iran J Reprod Med 2015; 13(8): 513-516. [Article]
10. Ray A, Shah A, Gudi A, et al. Unexplained infertility: an update and review of practice. Reprod Biomed Online 2012; 24(6): 591-602. [DOI]
11. Cates W, Farley TM, Rowe PJ. Worldwide patterns of infertility: is Africa different? Lancet 1985; 2(8455): 596-598. [DOI]
12. Mirzaei M, Namiranian N, Firouzabadi RD, et al. The prevalence of infertility in 20-49 years women in Yazd, 2014-2015: A cross-sectional study. Int J Re-prod Biomed 2018; 16(11): 683-688. [Article]
13. Aliakbari F, Emadeddin M, Azizi F, et al. A survey on infertility in men and its relation to risk factors in selected provinces of Iran. JBRA Assist Reprod 2021; 25(4): 563-569. [DOI]
14. Concepción-Zavaleta MJ, Coronado-Arroyo JC, Qui-roz-Aldave JE,et al. Thyroid disfunction and female infertility. A comprehensive review. Diabetes Metab Syndr 2023; 17(11): 102876. [DOI]
15. Bosdou JK, Konstantinidou E, Anagnostis P, et al. Vitamin D and obesity: two interacting players in the field of infertility. Nutrients 2019; 11(7): 1455. [DOI]
16. Al-Otaibi ST. Male infertility among bakers associated with exposure to high environmental temperature at the workplace. J Taibah Univ Med Sci 2018; 13(2): 103-107. [DOI]
17. Zhang M-H, Shi ZD, Yu JC, et al. Scrotal heat stress causes sperm chromatin damage and cysteinyl aspartatespicific proteinases 3 changes in fertile men. J Assist Reprod Genet 2015; 32(5): 747–755. [DOI]
18. De Jong A, Menkveld R, Lens J, et al. Effect of alcohol intake and cigarette smoking on sperm parameters and pregnancy. Andrologia 2014; 46(2): 112-117. [DOI]
19. Mikkelsen EM, Riis AH, Wise LA, et al. Alcohol consumption and fecundability: prospective Danish cohort study. BMJ 2016; 354: i4262. [DOI]
20. Nagpal A, Girotra P, Nagpal D, et al. Study of the effect of smoking on sperm count in male infertility. Int J Gynaecol Obstet 2021; 5(5): 67-69. [DOI]
21. Hakim RB, Gray RH, Zacur H. Alcohol and caffeine consumption and decreased fertility. Fertil Steril 1998; 70(4): 632-637. [DOI]
22. Inhorn MC, Kobeissi L, Nassar Z, et al. Consanguinity and family clustering of male factor infertility in Lebanon. Fertil Steril 2009; 91(4): 1104-1109. [DOI]
23. Iqbal S, Zakar R, Fischer F, et al. Consanguineous marriages and their association with women’s re-productive health and fertility behavior in Pakistan: secondary data analysis from Demographic and Health Surveys, 1990–2018. BMC Women's Health 2022; 22(1): 118. [DOI]
24. Nussbaum RL, McInnes RR, Willard HF. Thompson & Thompson genetics in medicine e-book.8th ed. Philadelphia: Elsevier, 2016. [Article]
25. Pinborg A, Gaarslev C, Hougaard CO, et al. Influence of female bodyweight on IVF outcome: a longitudinal multicentre cohort study of 487 infertile cou-ples. Reprod Biomed Online 2011; 23(4): 490-499. [DOI]
26. Maghsoumi-Norouzabad L, Zare Javid A, Aiiashi S, et al. The impact of obesity on various semen parameters and sex hormones in Iranian men with infertility: A cross-sectional study. Res Rep Urol 2020; 12: 357-365. [DOI]
27. Bagwell MA, Thompson SJ, Addy CL, et al. Primary infertility and oral contraceptive steroid use. Fertil Steril 1995; 63(6): 1161-1166. [DOI]
28. Pinkerton GD, Carey HM. Post-pill infertility. Med J Aust. 1976; 1(8): 223-224. [Article]
29. Emokpae MA, Brown SI. Effects of lifestyle factors on fertility: practical recommendations for modification. Reprod Fertil 2021; 2(1): R13-R26. [DOI]
30. Alibeigi Z, Jafari-Dehkordi E, Kheiri S, et al. The impact of traditional medicine-based lifestyle and diet on infertility treatment in women undergoing assisted reproduction: a randomized controlled trial. Complement Med Res 2020; 27(4): 230-241. [DOI]

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