[Home ] [Archive]   [ فارسی ]  
:: Main :: About :: Current Issue :: Archive :: Search :: Submit :: Contact ::
:: Volume 10, Issue 1 (Vol. 10, No. 1, September 2007 2007) ::
Iran South Med J 2007, 10(1): 34-39 Back to browse issues page
Efficacy of intramuscular single dose of ceftriaxon versus ten days amoxicillin for treatment of children with acute otitis media
Ali Akbar Rahbari manesh Mr, Afshin Shirkani Mr 1, Hooshang Akhtar Khavari Mr, Peyman Salamaty Mr
1- , shirkani@Razi.tums.ac.ir
Abstract:   (10446 Views)
Background: Ceftriaxone is a prolonged third-generation cephalosporin and its intramuscular single dose can provide the necessary serum level against typical pathogens of acute otitis media up to 72 hours. Methods: In a prospective, randomized clinical trial study, the efficacy of intramuscular single dose of ceftriaxone (50mg/kg/dose) was compared to 10 days amoxicillin (50mg/kg/day, divided 3 time per day) to treat acute otitis media in children. A total of 110 children aged 5 months to 12 years, with uncomplicated acute otitis media were randomly selected to receive either an oral suspension amoxicillin for 10 days or an intramuscular single dose of ceftriaxone. Results: Clinical manifestation and demographic characteristics were similar in both groups. In ceftriaxone group, 48 (88.9%) of 54 cases were recovered completely, and in amoxicilline group, the treatment was successful in 51 (99.1%) of 56 cases (p>0.05). In ceftriaxone, 2 cases and in amoxicilline group, 3 cases developed a skin rash (p>0.05). Conclusion: The efficacy of intramuscular single dose of ceftriaxone (50mg/kg) to treat uncomplicated acute otitis media in children is as effective as amoxicillin (50mg/kg/day, divided 3 times per day).
Keywords: ceftriaxone, amoxicillin, acute otitis media, antibiotic
Full-Text [PDF 164 kb]   (1477 Downloads)    
Type of Study: Original | Subject: General
Received: 2008/08/31 | Accepted: 2008/08/31 | Published: 2008/08/31
Send email to the article author

Add your comments about this article
Your username or Email:

CAPTCHA


XML   Persian Abstract   Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Rahbari manesh A A, Shirkani A, Akhtar Khavari H, Salamaty P. Efficacy of intramuscular single dose of ceftriaxon versus ten days amoxicillin for treatment of children with acute otitis media. Iran South Med J. 2007; 10 (1) :34-39
URL: http://ismj.bpums.ac.ir/article-1-5-en.html


Volume 10, Issue 1 (Vol. 10, No. 1, September 2007 2007) Back to browse issues page
دانشگاه علوم پزشکی بوشهر، طب جنوب ISMJ

Iranian South Medical Journal is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License which allows users to read,
copy, distribute and make derivative works for non-commercial purposes from the material, as long as the author of the original work is cited properly

Copyright © 2017, Iranian South Medical Journal| All Rights Reserved

Persian site map - English site map - Created in 0.06 seconds with 32 queries by YEKTAWEB 4137