[Home ] [Archive]   [ فارسی ]  
:: Main :: About :: Current Issue :: Archive :: Search :: Submit :: Contact ::
:: Volume 17, Issue 2 (Iranian South Medical journal 2014) ::
Iran South Med J 2014, 17(2): 191-200 Back to browse issues page
Venom Apparatus Structure and Conutoxins Granules formation in Cone Snail (Conus coronatus) of Persian Gulf
Ferial Monsef1, Saber Khodabandeh 2, Iraj Nabipour3
1- Department of Marine Biology, Tarbiat Modares University, Tehran, IRAN
2- Department of Marine Biology, Tarbiat Modares University, Tehran, IRAN , skhoda@modares.ac.ir
3- The Persian Gulf Marine Biotechnology Research Center, the Persian Gulf Biomedical Research Center, Bushehr University of Medical Sceince, Bushehr, IRAN
Abstract:   (6382 Views)

Background: Today use conotoxin as a neurotoxin and cytotoxin in medical science is obvious. These compounds are produced by venomous cone snails. Toxins produced by the venom apparatus of this snail and injected into the prey. To obtain and identification of these toxins, study of venom apparatus and the manufacture formation is necessary. Materials and Methods: In order to study the organ, specimens of C. coronatus were collected from the Coast of Gheshm Island. After dissection were fixed in Bouin's for 48 hours and transferred to laboratory into 70% ethanol. After dehydration and Paraffin embedded were cutted by microtome and then collected on glass slides and stained then photographed and studied. Results: Observation showed that, the venom bulb was muscular and in their middle part a channel with epithelial cells was observable that secreted some material. Venom duct walls composed of 3 parts including the outer layer of connective tissue with muscle an inner layer of columnar epithelial cells with basal nucleus and the inner lumens which filled by the. Departed nucleus by secretion exist in all 3 part of venom duct. In radula sac sections, lots growing radula were observed. Conclusion: Venom bulb was a weak secretion role and venom duct near the pharynx have a more mature granule than the other part. Holocrine secretion happened in all part of venom duct. Most suitable part for extract the conotoxin was the venom bulb end part.

Keywords: Conus, Gheshm Island, Toxin, C. coronatus, Radula
Full-Text [PDF 824 kb]   (1442 Downloads)    
Type of Study: Original | Subject: General
Received: 2014/04/14 | Accepted: 2014/04/14 | Published: 2014/04/14
Send email to the article author

Add your comments about this article
Your username or Email:

CAPTCHA


XML   Persian Abstract   Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Monsef F, Khodabandeh S, Nabipour I. Venom Apparatus Structure and Conutoxins Granules formation in Cone Snail (Conus coronatus) of Persian Gulf. Iran South Med J. 2014; 17 (2) :191-200
URL: http://ismj.bpums.ac.ir/article-1-525-en.html


Volume 17, Issue 2 (Iranian South Medical journal 2014) Back to browse issues page
دانشگاه علوم پزشکی بوشهر، طب جنوب ISMJ

Iranian South Medical Journal is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License which allows users to read,
copy, distribute and make derivative works for non-commercial purposes from the material, as long as the author of the original work is cited properly

Copyright © 2017, Iranian South Medical Journal| All Rights Reserved

Persian site map - English site map - Created in 0.05 seconds with 32 queries by YEKTAWEB 4144