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:: Volume 17, Issue 2 (Iranian South Medical journal 2014) ::
Iran South Med J 2014, 17(2): 223-232 Back to browse issues page
Comparison of antibiotic resistance of bacterial agents associated in septicaemia in children and infants
Mohammad Kazem Sharifi Yazdi1, Mohammad Taghi Haghi Ashtiani2, Bahram Nikmanesh2, Mohammad Mehdi Soltan Dallal 3
1- Zoonotic Diseases Research Centre, Tehran University of Medical Sciences, Tehran, IRAN.
Department of Medical Laboratory Sciences, School of Paramedical Sciences, Tehran University of Medical Sciences, Tehran, IRAN.
2- Laboratory, Children’s Medical Center, Tehran University of Medical Sciences, Tehran, IRAN
3- Division of Microbiology, Department of Pathobiology, School of Public Health, Tehran University of Medical Sciences, Tehran, IRAN.
Food Microbiology Research Center, Tehran University of Medical Sciences, Tehran, IRAN. , msoltandallal@gmail.com
Abstract:   (5716 Views)

Background: Septicaemia is a leading cause of morbidity and mortality of infant’s and childerens espicially in first week of their life, both in developed and underdeveloped countries.The aim of this research was to study of bacterial agents causing septicaemia and to determine their antibiotic suseptibility patternes. Materials and Methods : This was a descriptive study, it was performed during eight months from October 2011 till May 2011.In total 216 blood culture samples of children suspected of septicaemia in children health centre hospital were send to the laboratory for investigation. The bacterial identification was carried out by culturing and conventional biomedical tests. The antibiotic sensitivity tests were performed by disk diffusion method. These data are analyzed by SPSS and the results Expressed as relative frequencies. Results: Out of 216 tested samples 55(25.6%) were positive and 161 (74.54%) negative. The dominated bacteria was Escherichia coli (31.42%), followed by Staphylococcus aureus (22.86 %), Klebsiella pneumonia (20%)), Staphylococcus epidermidis (14.28%), Streptococcus pneumonia (2.86%), Salmonella typhi (2.86%), Enterobacter cloacae (2.86%) and Stenotrophomonas maltophilia (2.86%). In general gram-negative bacteria were isolated more than gram-positive. Staphylococcus bacteria were more resistant to antibiotics than other isolated bacteria, and were 100% resistant to penicillin. The enterobacteriaceae were more sensitive to norfloxacin, amikacin, tobramycin, and they were 100% resistant to ampicillin. Conclusion: The results obtained in this study showed that gram-negative bacteria are more responsible in septicaemia in children ward, and norfloxacin is the more effective antibiotic in comparison with others.

Keywords: septicaemia, infants, bacterial agent, antibiotic resistance
Full-Text [PDF 671 kb]   (1434 Downloads)    
Type of Study: Original | Subject: General
Received: 2014/04/14 | Accepted: 2014/04/14 | Published: 2014/04/14
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Sharifi Yazdi M K, Haghi Ashtiani M T, Nikmanesh B, Soltan Dallal M M. Comparison of antibiotic resistance of bacterial agents associated in septicaemia in children and infants. Iran South Med J. 2014; 17 (2) :223-232
URL: http://ismj.bpums.ac.ir/article-1-529-en.html


Volume 17, Issue 2 (Iranian South Medical journal 2014) Back to browse issues page
دانشگاه علوم پزشکی بوشهر، طب جنوب ISMJ

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