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:: Volume 17, Issue 3 (Iranian South Medical journal 2014) ::
Iran South Med J 2014, 17(3): 290-297 Back to browse issues page
Evaluating effect of a new sterile gauze containing Bentonite and Halloysite minerals on blood coagulation and wound healing in male rats
Mehrosadat Alavi1, Farshid Gheisari1, Mahdi Haghighatafshar2, Mohammad Ali Okhovat3, Peyman Rezaei4, Alireza Totonchi4, Mohammad Atefi5
1- Ionizing and Non-Ionizing Radiation Protection Research Center, School of Paramedical Sciences, Shiraz University of Medical Sciences, Shiraz, IRAN.
2- Nuclear Medicine and Molecular Imaging Research Center, Nemazee Hospital, Shiraz University of Medical Sciences, Shiraz, IRAN
3- Diagnostic Laboratory Sciences and Technology Research Center, School of Paramedical Sciences, Shiraz University of Medical sciences, Shiraz, IRAN
4- Student Research Committee, School of Paramedical Sciences, Shiraz University of Medical Sciences, Shiraz, IRAN.
5- Ionizing and Non-Ionizing Radiation Protection Research Center, School of Paramedical Sciences, Shiraz University of Medical Sciences, Shiraz, IRAN , mohmmad.atefi@yahoo.com
Abstract:   (9932 Views)

Background: In recent years, a wide variety of researches are performed in the field of novel technologies to stop severe bleeding. Finally, an effective combination of a mineral called Zeolite has been introduced. Bentonite and Halloysite ores are very common in Iran. Likewise, coagulation properties of these minerals have been proven in several studies. In this study, the effect of new recombinant gauze, containing Bentonite and Halloysite minerals was studied on blood coagulation and wound healing time in male rats. Materials and methods: In this exprimental study, new sterile gauze was prepared from mixture of Bentonite and Halloysite minerals and Vaseline. Then the effect of gauze was studied on the wound healing process in the Wistar rat. Finally, SPSS software was used for data analysis (T-test and the nonparametric Mann-Whitney). Differences with P <0.05 were considered as significant. Results: In the first phase, the study was carried out on 40 blood samples of mice tails. The coagulation time of 81.31 ± 19.12 sec in control group and 33.2 ± 2.18 sec in study group (Bentonite-Halloysite treated) were reported. In the second phase, the time of complete wound healing was considered. This figure was observed between 9 and 13 days in the control group and 5 to 6 days in study group which is treated with recombinant sterile gauze. Conclusion: According to the results of the present study, topical application of the new sterile gauze, combined with Bentonite and Halloysite minerals decrease clotting and wound healing time significantly

Keywords: Sterile gauze, Bentonite, Halloysite, Wound healing, Clotting time
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Type of Study: Original | Subject: General
Received: 2012/12/23 | Accepted: 2013/03/2 | Published: 2014/06/14
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Alavi M, Gheisari F, Haghighatafshar M, Okhovat M A, Rezaei P, Totonchi A et al . Evaluating effect of a new sterile gauze containing Bentonite and Halloysite minerals on blood coagulation and wound healing in male rats. Iran South Med J. 2014; 17 (3) :290-297
URL: http://ismj.bpums.ac.ir/article-1-541-en.html


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Volume 17, Issue 3 (Iranian South Medical journal 2014) Back to browse issues page
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