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:: Volume 17, Issue 3 (Iranian South Medical journal 2014) ::
Iran South Med J 2014, 17(3): 298-306 Back to browse issues page
Evaluation of Polyethylen - Vazeline guaze and melolin on healing of graft donor sites in rat
Mohammad Javad Fatemi1, Mohammad Pegahmehr2, Amir Assadollah Khajerahimi3, Mahnaz Chahardouli4, Shahrzad Taghavi4, Shabnam Mostafavi4, Maryam Sakhae4, Pegah Nafar4
1- Department of Plastic Reconstructive Surgery, Burn Research Center, Hazrat Fatima Hospital, Iran University of Medical Sciences, Tehran, IRAN , Mjfatemi41@gmail.com
2- General Surgery, Burn research Center, Iran University of Medical University.Tehran, IRAN
3- Department of Plastic Reconstructive Surgery, Burn Research Center, Hazrat Fatima Hospital, Iran University of Medical Sciences, Tehran, IRAN
4- Burn Resaerch Center, Iran University of Medical Sciences, Tehran, IRAN
Abstract:   (9570 Views)

Background: Different types of dressings are applied on wounds to accelerate the healing process and improve its long term outcomes. This study designed to compare the healing rate of skin graft donor site while dressed with polyethylene, Meloline and Vaseline in rats. Material and Methods: In an experimental study, polyethylen, vazeline gauze and melolin were used for skin grft donor site dressing. 30 rats, randomly assigned to 3 groups. An approximately 5x5 cm split thickness wound was made on the dorsum of each rat under general anesthesia. Then dressed by polyethylene, Vaseline gauze and Melolin in each group. The wound size was measured by Image J sotware after operation and on days 3, 6, 9 and 12 to evaluate the rate of healing, then the results compared between groups. Results: The mean area of the wound size on day 12 was 0.72±0.44 cm2 in Vaseline group, 0.68±0.75 cm2 in polyethylene group and 0.14±0.17 cm2 in Meloline group.In 3rd day Vaseline group had smaller size, but in days 6 and 9 the smaller size belonged to Meloline similar to day 12, which differed statistically with Vaseline.P<0.04 Conclusion: Polyethylene dressing according to its low price and acceptable rate of wound healing may be an appropriate choice for wounds’ dressing.

Keywords: wound dressing, wound healing, skin graft donor site, Meloline, Polyethylene, Vaseline
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Type of Study: Original | Subject: General
Received: 2012/08/28 | Accepted: 2012/10/13 | Published: 2014/06/14
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Fatemi M J, Pegahmehr M, Khajerahimi A A, Chahardouli M, Taghavi S, Mostafavi S, et al . Evaluation of Polyethylen - Vazeline guaze and melolin on healing of graft donor sites in rat. Iran South Med J. 2014; 17 (3) :298-306
URL: http://ismj.bpums.ac.ir/article-1-542-en.html


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Volume 17, Issue 3 (Iranian South Medical journal 2014) Back to browse issues page
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