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:: Volume 18, Number 6 (Iranian South Medical Journal 2016) ::
Iran South Med J 2016, 18(6): 1208-1220 Back to browse issues page
Assessment of Anti- Inflammatory effect of sea urchin Echinometra mathaei From the Persian Gulf
Solmaz Soleimani1, Morteza Yousefzadi *2, Sohila Moein3, Narges Amrollahi Bioki1
1- Department of marine biology, Faculty of Marine Science and technology, Hormozgan University, Bandar Abbas, Iran
2- Department of marine biology, Faculty of Marine Science and technology, Hormozgan University, Bandar Abbas, Iran , morteza110110@gmail.com
3- Department biochemistry & Molecular medicine research center, Faculty of Medical Sciences, Hormozgan University, Bandar Abbas, Iran
Abstract:   (1146 Views)

Background: sea urchins belonging to phylum echinoderms of marine invertebrates them found to possess excellent. Inflammation can be considered a set of complex processes that many body systems including the immune and nervous system are involved. The aim of the present research was undertaken to study the anti- inflammatory activity of different extracts, coelomic fluid and pigments shells and spines of sea urchin of Echinodermata mathaei.

Material and method: Isolation of different tissues extracts (spine, shell, gonad and aristotol lantern) sea urchin by three solvents (n- hexan, ethyl acetate, methanol). Isolation coelomic fluid by buffered mode and pigments shell and spine by HCl of sea urchin evaluation antioxidant (DPPH radical scavenging) and anti- inflammatory activity investigated through inhibition albumin serum denaturation.

Resuts: According to the results of the study, the spine- methanoli and coelomic fluid (CF) had the highest activity in the DPPH radical scavenging and aristotol lantern- ethyl acetate and pigment shell highest activity in the anti- inflammatory methods. Significant differences were observed at P<0.05.

Conclusion: The result of this research indicated that sea urchin of E.mathaei due to the high antioxidant activity, have anti- inflammatory activities too.

Keywords: Anti- inflammatory activity, sea urchin, Echinodermata mathaei, Persian Gulf
Full-Text [PDF 820 kb]   (602 Downloads)    
Type of Study: Original | Subject: Pharmacology
Received: 2015/12/22 | Accepted: 2015/12/22 | Published: 2015/12/22
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DOI: 10.7508/ismj.1394.06.011


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Soleimani S, Yousefzadi M, Moein S, Amrollahi Bioki N. Assessment of Anti- Inflammatory effect of sea urchin Echinometra mathaei From the Persian Gulf. Iran South Med J. 2016; 18 (6) :1208-1220
URL: http://ismj.bpums.ac.ir/article-1-754-en.html
Volume 18, Number 6 (Iranian South Medical Journal 2016) Back to browse issues page
دانشگاه علوم پزشکی بوشهر، طب جنوب ISMJ

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