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:: Volume 18, Number 6 (Iranian South Medical Journal 2016) ::
Iran South Med J 2016, 18(6): 1270-1286 Back to browse issues page
Bryozoans, the remedy hidden treasures of oceans: secondary metabolites
Gholamhosean Mohebbi1, Iraj Nabipour1, Seyedeh Samira Arshadi *2
1- The Persian Gulf Marine Biotechnology Research Center, The Persian Gulf Biomedical Research Institute, Bushehr University of Medical Sciences, Bushehr, Iran
2- The Persian Gulf Marine Biotechnology Research Center, The Persian Gulf Biomedical Research Institute, Bushehr University of Medical Sciences, Bushehr, Iran , samiraarshadi@ymail.com
Abstract:   (1337 Views)

Bryozoans, commonly known as “moss animals”, are typically aquatic, filter feeding, sessile, colonial marine animals. Although, they are a rich resource of new bioactive secondary metabolites, but studies on their secondary metabolite have been neglected. Although over 8000 species are known, the lowest numbers of novel compounds were isolated from the phylum Bryozoa. In addition, presently nothing is recognized regarding the origin of the bioactive compounds isolated by bryozoans. At present nothing is known regarding the origin of the natural products isolated by bryozoans. The most famous of compounds obtained from these organisms are macrolide lactones of Bryostatins. They are potent modulators of protein kinase C. The amazing compounds such as Flustramines, Hinckdentine, Convolutamines, Kororamides, Chatellines, Chartellamides, Convolutamines, Convolutamidines, euthyroideone, amathaspiramide, lutamides, Volutamides, tambjamines, Phidolopins, and dozens of other compounds with different biological properties have been obtained. Very few studies have been done on these treasures in the sea depth, and more studies need to be done on them for access to their secondary metabolites.

Keywords: Bryozoans, Bryostatin, Flustramine, Secondary metabolites
Full-Text [PDF 1257 kb]   (644 Downloads)    
Type of Study: Review | Subject: Pharmacology
Received: 2015/12/22 | Accepted: 2015/12/22 | Published: 2015/12/22
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DOI: 10.7508/ismj.1394.06.017


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Mohebbi G, Nabipour I, Arshadi S S. Bryozoans, the remedy hidden treasures of oceans: secondary metabolites. Iran South Med J. 2016; 18 (6) :1270-1286
URL: http://ismj.bpums.ac.ir/article-1-761-en.html
Volume 18, Number 6 (Iranian South Medical Journal 2016) Back to browse issues page
دانشگاه علوم پزشکی بوشهر، طب جنوب ISMJ

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