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:: Volume 19, Number 1 (Iranian South Medical Journal 2016) ::
Iran South Med J 2016, 19(1): 155-166 Back to browse issues page
Beneficial effects of resveratrol on reducing blood glucose and insulin resistance in T2DM
Ali Movahed *
The Persian Gulf Tropical Medicine Research Center, The Persian Gulf Biomedical Research Institute, Bushehr University of Medical Sciences, Bushehr, Iran , amovahed58@gmail.com
Abstract:   (1692 Views)

In recent years, the active compounds from the plants and fruits, which have been used in the human foods regimen, have received increased attention in medical research. Therefore, the side effects of chemical drugs and their complications have persuaded the scientists to look into the active compounds of fruits and plants, to find their useful effects in prevention and treatment of different diseases. One of such compounds is resveratrol, a natural poly phenol found prefavorably in grapes and berries. Its useful effects on metabolic syndrome, including cardiovascular diseases, fatness and T2DM, have been extensively studied in animal models and human clinical trials. In fact the results from numerous studies have shown that resveratrol may be useful in the prevention and even treatment of type 2 Diabetes. Over the past two decades, the results of investigations conducted on animal models and clinical trials on human and, meta analysis applied, regarding the effectiveness of resveratrol in reducing fasting blood sugar and insulin resistance have been promising. Therefore, in this review I will discuss the useful effects of resveratrol and its mechanism of action on type 2 Diabetes and related parameters, in different models including animals and human clinical trials.   

Keywords: Resveratrol, type 2 diabetes, mechanism of action, metabolic syndrome, insulin resistance
Full-Text [PDF 399 kb]   (616 Downloads)    
Type of Study: Review | Subject: Endocrine System
Received: 2016/02/25 | Accepted: 2016/02/25 | Published: 2016/02/25
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DOI: 10.7508/ismj.1395.01.013
PMID: 26879600
PMCID: PMC4825102


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Movahed A. Beneficial effects of resveratrol on reducing blood glucose and insulin resistance in T2DM. Iran South Med J. 2016; 19 (1) :155-166
URL: http://ismj.bpums.ac.ir/article-1-779-en.html
Volume 19, Number 1 (Iranian South Medical Journal 2016) Back to browse issues page
دانشگاه علوم پزشکی بوشهر، طب جنوب ISMJ

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