Volume 7, Issue 2 (Iranian south medical of journals 2005)
Iran South Med J 2005, 7(2): 122-127 |
Back to browse issues page
Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
Shariati M. Genetic epidemiology of Down syndrome in Iran. Iran South Med J 2005; 7 (2) :122-127
URL: http://ismj.bpums.ac.ir/article-1-91-en.html
URL: http://ismj.bpums.ac.ir/article-1-91-en.html
, shariatymk@yahoo.com
Abstract: (21793 Views)
Down syndrome is the most common autosomal abnormality and occurs in approximately 1 per 700 live births. Down syndrome accounts for about one third of all moderate and sever mental handicaps in school-aged children. To reveal genetic epidemiology of Down syndrome, 545 karyotypes of referred cases to the author were evaluated. The frequencies of three cytogenetic variants of Down syndrome were trisomy 21 (77.5%), mosaicism (18%) and chromosomal translocation (4.5%). Male to female ratio was 1.34. The mean age of their mothers and fathers were 29.03 years (median=27 years) and 34.6 years (median=33 years), respectively. Therefore, mean age of Iranian mothers with Down syndrome is six years less than those in the western countries.
Type of Study: Original |
Subject:
General
Received: 2009/01/17 | Accepted: 2009/01/17 | Published: 2009/01/17
Received: 2009/01/17 | Accepted: 2009/01/17 | Published: 2009/01/17
Send email to the article author
| Rights and Permissions | |
 |
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |
