[Home ] [Archive]   [ فارسی ]  
:: Main :: About :: Current Issue :: Archive :: Search :: Submit :: Contact ::
:: Volume 22, Issue 6 (Iranian South Medical Journal 2020) ::
Iran South Med J 2020, 22(6): 381-391 Back to browse issues page
Relationship between Baseline ECG Abnormalities and Quantitative Perfusion Parameters of Myocardial Perfusion Findings
Tahereh Ghaedian 1, Mandana Mirzaei2, Mohammad Mehdi Ghaedian3
1- Nuclear Medicine and Molecular Imaging Research Center, Namazi Hospital, Shiraz University of Medical Sceinces, Shiraz, Iran , tghaedian@gmail.com
2- Nuclear Medicine and Molecular Imaging Research Center, Namazi Hospital, Shiraz University of Medical Sceinces, Shiraz, Iran
3- Kowsar Hospital, Shiraz, Iran
Abstract:   (1672 Views)
Background: Coronary Artery Disease (CAD) is one of the major causes of mortality in most countries. Electrocardiography (ECG) and myocardial perfusion imaging (MPI) are non-invasive disgnostic tests for CAD. Finding a relationship between abnormal findings in the baseline ECG and MPI findings can be helpful in better diagnosis of CAD.
Materials and Methods: The present study examined ECG of patients who underwent MPI and categorized them into three groups: normal ECG, abnormal ST-T change, and abnormal Q or fragmented QRS. The quantitative and semi-quantitative parameters as well as visual interpretation of MPI were compared among the three groups.
Results: Finally, 230 patients entered the study, including 92 patients (40.0%) with normal ECG, 86 patients (37.4%) with ST-T changes and 52 patients (22.6%) with fQRS-Q complex abnormality. In total, 77 patients (33.5%) had positive MPI scan. There were significant differences between the normal and ST-T subgroups with Q-fQRS group for all quantitative and semi-quantitative variables, however, normal and ST-T groups were significantly different only in terms of SSS, SDS and TPDs. Frequency of abnormal MPI was significantly higher in Q-fQRS group.
Conclusion: The results of this study showed that myocardial ischemia is more frequent in patients with baseline ST-T ECG changes. In addition, Q-fQRS abnormality is associated with higher rates of both myocardial scar and ischemia in MPI.
Keywords: Electrocardiography, Myocardial Perfusion Imaging, Coronary Artery Disease, Quantitative and Semiquantitative MPI Perfusion Parameters
Full-Text [PDF 760 kb]   (567 Downloads)    
Type of Study: Original | Subject: Cardiovascular System
Received: 2019/06/30 | Accepted: 2019/10/22 | Published: 2020/01/28
1. Zipes DP, Libby P, Bonow RO, et al. Braunwald's Heart Disease E-Book: A Textbook of Cardiovascular Medicine. Elsevier Health Sciences, 2018, 2040.
2. Members WG, Doherty JU, Kort S, et al. ACC/AATS/AHA/ASE/ASNC/HRS/SCAI/SCC T/SCMR/STS 2019 Appropriate Use Criteria for Multimodality Imaging in the Assessment of Cardiac Structure and Function in Nonvalvular Heart Disease: A Report of the American College of Cardiology Appropriate Use Criteria Task Force, American Association for Thoracic Surgery, American Heart Association, American Society of Echocardiography, American Society of Nuclear Cardiology, Heart Rhythm Society, Society for Cardiovascular Angiography and Interventions, Society of Cardiovascular Computed Tomography, Society for Cardiovascular Magnetic Resonance, and the Society of Thoracic Surgeons. J Am Soc Echocardiog 2019; 32(5): 553-79.
3. Assadi M, Nabipour I, Saghari Met al. The role of myocardial perfusion imaging in the screening of silent ischemia in diabetic patients. Iran South Med J 2010; 13(1): 59-71.
4. Bonakdar H, Moladoust H, Kheirkhah J, et al. Significance of a Fragmented QRS Complex in Patients with Chronic Total Occlusion of Coronary Artery without Prior Myocardial Infarction. Anatol J Cardiol 2016; 16(2): 106-12. [DOI:10.5152/akd.2015.5887]
5. Nijveldt R, Beek AM, Hirsch A, et al. Functional Recovery after Acute Myocardial Infarction: Comparison between Angiography, Electrocardiography, and Cardiovascular Magnetic Resonance Measures of Microvascular Injury. J Am Coll Cardiol 2008; 52(3): 181-9. [DOI:10.1016/j.jacc.2008.04.006]
6. Shafiee E, Nabipour I, Jafary SM, et al. The association of metabolic syndrome and ischemic heart disease using resting electrocardiogram in the Northern Persian Gulf adults. Iran South Med J 2005; 7(2): 154-161.
7. Kakhki VRD, Ayati N, Zakavi SR, et al. Comparison between Fragmented QRS and Q Waves in Myocardial Scar Detection Using Myocardial Perfusion Single Photon Emission Computed Tomography. Kardiol Pol 2015; 73(6): 437-44. [DOI:10.5603/KP.a2014.0242]
8. Higgins JP, Williams G, Nagel JS, et al. Left Bundle-Branch Block Artifact on Single Photon Emission Computed Tomography with Technetium Tc 99m (Tc-99m) Agents: Mechanisms and a Method to Decrease False-Positive Interpretations. Am Heart J 2006; 152(4): 619-26. [DOI:10.1016/j.ahj.2006.06.009]
9. Caliskan B, Korkmaz A, Erdem F. Contribution of Fragmented QRS on Myocardial Perfusion Imaging in the Assessment of Functionally Significant Coronary Artery Stenoses. Eur Rev Med Pharmacol Sci 2016; 20(8): 1575-81.
10. Erdogan T, Kocaman SA, Çetin M, et al. Relationship of Fragmented QRS Complexes with Inadequate Coronary Collaterals in Patients with Chronic Total Occlusion. J Cardiovasc Med 2012; 13(8): 499-504. [DOI:10.2459/JCM.0b013e328353683c]
11. Eyuboglu M, Kucuk U, Senarslan O, et al. Comparison of the Presence of Fragmented QRS Complexes in the Inferior Versus the Anterior Leads for Predicting Coronary Artery Disease Severity. Rev Port Cardiol 2017; 36(2): 89-93. [DOI:10.1016/j.repc.2016.07.008]
12. Hizal Erdem F, Tavil Y, Yazici H, et al. Association of Fragmented QRS Complex with Myocardial Reperfusion in Acute ST‐Elevated Myocardial Infarction. Ann Noninvasive Electrocardiol 2013; 18(1): 69-74. [DOI:10.1111/anec.12011]
13. Kang X, Berman DS, Lewin HC, et al. Comparative Localization of Myocardial Ischemia by Exercise Electrocardiography and Myocardial Perfusion SPECT. J Nucl Cardiol 2000; 7(2): 140-5. [DOI:10.1016/S1071-3581(00)90034-5]
14. Farahani B, Skandari R, Abbasi MA, et al. The Association between Myocardial Perfusion Scan and Electrocardiographic Findings among Patients with Myocardial Ischemia. Int J Cardiovasc Pract 2017; 2(1): 17-20. [DOI:10.21859/ijcp-020108]
15. Mahmoodzadeh S, Moazenzadeh M, Rashidinejad H, et al. Diagnostic Performance of Electrocardiography in the Assessment of Significant Coronary Artery Disease and its Anatomical Size in Comparison with Coronary Angiography. J Res Med Sci 2011; 16(6): 750-5.
16. Ashley EA, Raxwal V, Froelicher V. An Evidence-Based Review of the Resting Electrocardiogram as a Screening Technique for Heart Disease. Prog Cardiovasc Dis 2001; 44(1): 55-67. [DOI:10.1053/pcad.2001.24683]
17. Sawano M, Kohsaka S, Okamura T, et al. Independent Prognostic Value of Single and Multiple Non-Specific 12-Lead Electrocardiographic Findings for Long-Term Cardiovascular Outcomes: A Prospective Cohort Study. PloS One 2016; 11(6): e0157563. [DOI:10.1371/journal.pone.0157563]
18. Prineas RJ, Grandits G, Rautaharju PM, et al. Long-Term Prognostic Significance of Isolated Minor Electrocardiographic T-Wave Abnormalities in Middle-Aged Men Free of Clinical Cardiovascular Disease (The Multiple Risk Factor Intervention Trial [MRFIT]). Am J Cardiol 2002; 90(12): 1391-5. [DOI:10.1016/S0002-9149(02)02881-3]
19. Farhan HL, Hassan KS, Al-Belushi A, et al. Diagnostic Value of Electrocardiographic T Wave Inversion in Lead aVL in Diagnosing Coronary Artery Disease in Patients with Chronic Stable Angina. Oman Med J 2010; 25(2): 124-7. [DOI:10.5001/omj.2010.33]
20. Korkmaz A, Yildiz A, Demir M, et al. The Relationship between Fragmented QRS and Functional Significance of Coronary Lesions. J Electrocardiol 2017; 50(3): 282-6. [DOI:10.1016/j.jelectrocard.2017.01.005]
21. Ozdemir S, Tan YZ, Colkesen Y, et al. Comparison of Fragmented QRS and Myocardial Perfusion-Gated SPECT Findings. Nucl Med Commun 2013; 34(11): 1107-15. [DOI:10.1097/MNM.0b013e3283653884]
Send email to the article author

Add your comments about this article
Your username or Email:


XML   Persian Abstract   Print

Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Ghaedian T, Mirzaei M, Ghaedian M M. Relationship between Baseline ECG Abnormalities and Quantitative Perfusion Parameters of Myocardial Perfusion Findings. Iran South Med J. 2020; 22 (6) :381-391
URL: http://ismj.bpums.ac.ir/article-1-1200-en.html

Volume 22, Issue 6 (Iranian South Medical Journal 2020) Back to browse issues page
دانشگاه علوم پزشکی بوشهر، طب جنوب ISMJ

Iranian South Medical Journal is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License which allows users to read,
copy, distribute and make derivative works for non-commercial purposes from the material, as long as the author of the original work is cited properly

Copyright © 2017, Iranian South Medical Journal| All Rights Reserved

Persian site map - English site map - Created in 0.04 seconds with 30 queries by YEKTAWEB 4313