Volume 26, Issue 1 (Iranian South Medical Journal 2023)
Iran South Med J 2023, 26(1): 63-76 |
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Tehranian N, Alijanpour M, Mohammadi E, Hosseini R A. The Relationship Between Postpartum Women's Sexual Function with the Type of Delivery and the Serum Concentration of Omentin-1 as a Predictive Biomarker. Iran South Med J 2023; 26 (1) :63-76
URL: http://ismj.bpums.ac.ir/article-1-1799-en.html
URL: http://ismj.bpums.ac.ir/article-1-1799-en.html
1- Department of Reproductive Health, School of Medical Sciences, Tarbiat Modares University, Tehran, Iran
2- Department of Reproductive Health, School of Medical Sciences, Tarbiat Modares University, Tehran, Iran
Department of Midwifery and reproductive health, School of Nursing and Midwifery, Babol University of Medical Sciences, Babol, Iran ,masoomalijanpoor@yahoo.com
3- Department of Nursing, School of Medical Sciences, Tarbiat Modares University, Tehran, Iran
4- Nursing and Midwifery Care Research Center, Department of Community Health and geriatric nursing, School of Nursing and Midwifery, Iran University of Medical Sciences, Tehran, Iran
2- Department of Reproductive Health, School of Medical Sciences, Tarbiat Modares University, Tehran, Iran
Department of Midwifery and reproductive health, School of Nursing and Midwifery, Babol University of Medical Sciences, Babol, Iran ,
3- Department of Nursing, School of Medical Sciences, Tarbiat Modares University, Tehran, Iran
4- Nursing and Midwifery Care Research Center, Department of Community Health and geriatric nursing, School of Nursing and Midwifery, Iran University of Medical Sciences, Tehran, Iran
Abstract: (1071 Views)
Background: Sexual function can be affected by hormonal changes, and recent studies indicate changes in the serum level of adipokines after childbirth. The present study aimed to investigate the relationship between sexual function after birth, the type of delivery, and the serum concentration of omentin-1.
Materials and Methods: This prospective cohort study was conducted in 89 women who were in the third trimester of pregnancy and met the inclusion criteria. The mother's serum omentin-1 concentration was measured in the first 24 hours after delivery, and its relationship with postpartum sexual function was evaluated according to the effect of delivery type.
Results: The results of the analysis showed that there was no significant relationship between sexual function and the type of delivery (P≥0.05). Also, serum levels of omentin-1 in the first 24 hours after vaginal delivery were higher than cesarean, but this relationship was not significant (P= 0.948). The results of Pearson's correlation test, between the serum level of oemantin-1 and sexual function in the vaginal delivery group showed that omentin-1 has a significant and inverse relationship with sexual function in the third trimester of pregnancy and the 12th week postpartum. (Respectively r= -0.317, p= 0.034 and r= -0.327, p= 0.028).
Conclusion: The results of the present study showed that the type of delivery had no significant relationship with sexual function. Also, the serum level of omentin-1 in the first 24 hours was higher in vaginal delivery than in cesarean. It can be concluded that the higher level of omentin-1 in mothers with vaginal delivery may act as a protective factor against metabolic disorders.
Materials and Methods: This prospective cohort study was conducted in 89 women who were in the third trimester of pregnancy and met the inclusion criteria. The mother's serum omentin-1 concentration was measured in the first 24 hours after delivery, and its relationship with postpartum sexual function was evaluated according to the effect of delivery type.
Results: The results of the analysis showed that there was no significant relationship between sexual function and the type of delivery (P≥0.05). Also, serum levels of omentin-1 in the first 24 hours after vaginal delivery were higher than cesarean, but this relationship was not significant (P= 0.948). The results of Pearson's correlation test, between the serum level of oemantin-1 and sexual function in the vaginal delivery group showed that omentin-1 has a significant and inverse relationship with sexual function in the third trimester of pregnancy and the 12th week postpartum. (Respectively r= -0.317, p= 0.034 and r= -0.327, p= 0.028).
Conclusion: The results of the present study showed that the type of delivery had no significant relationship with sexual function. Also, the serum level of omentin-1 in the first 24 hours was higher in vaginal delivery than in cesarean. It can be concluded that the higher level of omentin-1 in mothers with vaginal delivery may act as a protective factor against metabolic disorders.
Type of Study: Original |
Subject:
Obstetrics
Received: 2023/08/25 | Accepted: 2023/10/14 | Published: 2023/11/14
Received: 2023/08/25 | Accepted: 2023/10/14 | Published: 2023/11/14
References
1. Fanshawe AM, De Jonge A, Ginter N, et al. The Impact of Mode of Birth, and Episiotomy, on Postpartum Sexual Function in the Medium-and Longer-Term: An Integrative Systematic Review. IntJEnvironResPublicHealth 2023; 20(7): 5252. [DOI]
2. Jamali S, Inaloo R, Javadpour S, et al. The Relationship between Sexual Function and Quality ofLife in Reproductive-age grouped Women in Iran: A Cross-Sectional Study. Ambient Sci 2018; 5: 1-5. [DOI]
3. Ahmadi F, Tahmasebi R, Noroozi A, et al. Prevalence of and Factors Affecting Sexual Dysfunction in Women of Reproductive Age. Iran South Med J 2022; 25(2): 114-129. [DOI]
4. Gutzeit O, Levy G, Lowenstein L. Postpartum Female Sexual Function: Risk Factors for Postpartum Sexual Dysfunction. Sex Med 2020; 8(1): 8-13. [DOI]
5. Alijanpour M, Tehranian N, Mohammadi E, et al. Women's Perceptions and Experiences of the Concept of Postpartum Sexual Function: A Directed Qualitative Content Analysis. J Midwifery Reprod Health 2022; 10(2): 3290-3301. [DOI]
6. Chang SR, Chen KH, Lin HH, et al. Comparison of the effects of episiotomy and no episiotomy on pain, urinary incontinence, and sexual function 3 months postpartum: A prospective follow-up study. Int J Nurs Stud 2011; 48(4): 409-418. [DOI]
7. van Brummen HJ, Bruinse HW, van de Pol G, et al. Which factors determine the sexual function 1 year after childbirth?.BJOG 2006; 113(8): 914-918. [DOI]
8. WHO Statement on Caesarean Section Rates.WHO. (Accessed June 9, 2021, at https://www.who.int/news-room/questionsand-answers/item/who-statement-oncaesarean-section-rates-frequently-askedquestions). [Article]
9. Rebelo F, Franco-Sena AB, Struchiner CJ, et al. Changes in maternal plasma Adiponectin from late pregnancy to the postpartum period according to the mode of delivery: results from a prospective cohort in Rio de Janeiro, Brazil. PloS One 2016; 11(7): e0158886. [DOI]
10. Gutaj P, Sibiak R, Jankowski M, et al. The Role of the Adipokines in the Most Common Gestational Complications. Int J Mol Sci 2020; 21(24): 9408. [DOI]
11. Tan YL, Zheng XL, Tang CK. The protective functions of omentin in cardiovascular diseases. Clin Chim Acta 2015; 448: 98-106. [DOI]
12. Smitka K, Marešová D. Adipose tissue as an endocrine organ: an update on proinflammatory and anti-inflammatory microenvironment. Prague Med Rep 2015; 116(2): 87-111. [DOI]
13. Yang R, Xu M, Pray J, et al. Cloning of omentin, anew adipocytokine from omental fat tissue in humans. Diabetes 2003; 52(supplement 1): 1-A730. [Article]
14. Liu R, Wang XL, Bu P. Omentin-1 is associated with carotidatherosclerosis in patients with metabolic syndrome. Diabetes Res Clin Pract 2011; 93(1): 21-25. [DOI]
15. Rao SS, Hu Y, Xie PL, et al. Omentin-1 prevents inflammation-induced osteoporosis by downregulating the pro-inflammatory cytokines. Bone Res 2018; 6: 9. [DOI]
16. Cunningham FG, Leveno K, Dashe J, et al. Maternal Physiology. Williams Obstetrics. 26th ed. McGraw Hill, 2022, 67-102. [Article]
17. Barker G, Lim R, Georgiou HM, et al. Omentin-1 is decreased in maternal plasma, placenta and adipose tissue of women with pre-existing obesity. PloS One 2012; 7(8): e42943. [DOI]
18. Aktas G, Alçelik A, Ozlu T, et al. Association between omentin levels and insulin resistance in pregnancy. Exp Clin Endocrinol Diabetes 2014; 122(3): 163-6. [DOI]
19. Parvanehvar S, Tehranian N, Kazemnejad A, et al. Maternal omentin-1 level, quality of life and marital satisfaction in relation to mode of delivery: a prospective cohort study. BMC Pregnancy Childbirth 2020; 20(1): 136. [DOI]
20. Rosen R, Brown C, Heiman J, et al. The Female Sexual Function Index (FSFI): a multidimensional self-report instrument for the assessment of female sexual function. J Sex Marital Ther 2000; 26(2): 191-208. [DOI]
21. Mohammadi KH, Heydari M, Faghihzadeh S. The Female Sexual Function Index (FSFI): validation of the Iranian version. Payesh 2008; 7(3): 269-78. (Persian) [DOI]
22. Beck AT, Steer RA, Carbin MG. Psychometric properties of the Beck Depression Inventory: Twenty-five years of evaluation. Clin Psychol Rev 1988; 8(1): 77-100. [DOI]
23. Ghassemzadeh H, Mojtabai R, Karamghadiri N, et al. Psychometric properties of a Persian‐language version of the Beck Depression Inventory‐Second edition: BDI‐II‐PERSIAN. Depression Anxiety 2005; 21(4): 185-92. [DOI]
24. Baghdarin N, KhosraviAnbaran Z, Mazloum SR, et al. Comparison of sexual function of women after vaginal delivery and cesarean section in patients referred to health centers in Mashhad. IJOGI 2012; 15(30): 8-14. (Persian) [DOI]
25. Lurie S, Aizenberg M, Sulema V, et al. Sexual function after childbirth by the mode of delivery: a prospective study. Arch Gynecol Obstet 2013; 288(4): 785-792. [DOI]
26. Moghadam M, Zaheri F, ShamsAlizadeh N, et al. The Relationship Between the Type of Delivery and Sexual Function in Mothers Referring to Kourdistan (Sanandaj) Health Centers in 2015-2016. Crescent J med Biol Sci 2019; 6(4): 473-480. [Article]
27. Kahramanoglu I, Baktiroglu M, Hamzaoglu K, et al. The impact of mode of delivery on the sexual function of primiparous women: a prospective study. Arch Gynecol Obstet 2017; 295(4): 907-916. [DOI]
28. Hantoushzadeh S, Rajabzadeh A, Saadati A, et al. Caesarean or normal vaginal delivery: overview of physicians’ self-preference and suggestion to patients. Arch Gynecol Obstet 2009; 280(1): 33-37. [DOI]
29. Moghimi-Hanji S, Mahdizade-Torzani Z. A Comparative Sexual Function after Childbirth in Nulliparous Women who Delivered by Cesarean and Vaginal. Q Horizon Med Sci 2011; 18(5): 225-31. [Article]
30. Banaei M, Moridi A, Dashti S. Sexual Dysfunction and its Associated Factors After Delivery: Longitudinal Study in Iranian Women. Mater Sociomed 2018; 30(3): 198-203. [DOI]
31. Yan P, Xu Y, Zhang Z, et al. Association of Circulating Omentin-1 with Osteoporosis in a Chinese Type 2 Diabetic Population.Mediators Inflamm 2020; 2020: 9389720. [DOI]
32. De Souza A, Dwyer PL, Charity M, et al. The effects of mode delivery on postpartum sexual function: a prospective study. BJOG 2015; 122(10): 1410-8. [DOI]
33. Yang RZ, Lee MJ, Hu H, et al. Identification of omentin as a novel depot-specific adipokine in human adipose tissue: possible role in modulating insulin action. Am J Physiol Endocrinol Metab 2006; 290(6): E1253- E1261. [DOI]
34. Chen H, Montagnani M, Funahashi T, et al. Adiponectin stimulates production of nitric oxide in vascular endothelial cells. J biol Chem 2003; 278(45): 45021-45026. [DOI]
35. Brunetti L, Orlando G, Ferrante C, et al. Orexigenic effects of omentin-1 related to decreased CART and CRH gene expression and increased norepinephrine synthesis and release in the hypothalamus. Peptides 2013; 44: 66-74. [DOI]
36. Mahde A, Shaker M, Al-Mashhadani Z. Study of omentin1 and other adipokines and hormones in PCOS patients. Oman Med J 2009; 24(2): 108-18. [DOI]
37. El-Kaream SA, El-Monem SA, Mohassab GI, et al. Relationship between Testosterone Level, Serum Omentin-1 and Insulin Resistance in Obese Men. Am J Biomed Sci 2015. [DOI]
38. shahdaeizadeh S, Edalatmanesh MA, moghadasi M. Evaluation of sex hormones (FSH, Estrogen and Testostrone) changes during follicular and luteal phases and sexual dysfunction in women with Multiple Sclerosis. Pars J Med Sci 2015; 12(4): 23-30. (Persian) [DOI]
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