Volume 26, Issue 5 (Iranian South Medical Journal 2024)
Iran South Med J 2024, 26(5): 311-323 |
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Barazesh A, Heydari Z, Rahmani E, Shadvar N, Fouladvand M A. The Presence of anti-Toxoplasma Antibodies in Pregnant Women with Normal Pregnancy Course and with History of Spontaneous Abor-tion. Iran South Med J 2024; 26 (5) :311-323
URL: http://ismj.bpums.ac.ir/article-1-1869-en.html
URL: http://ismj.bpums.ac.ir/article-1-1869-en.html
1- Department of Microbiology & Parasitology, School of Medicine, Bushehr University of Medical Sciences, Bushehr, Iran
2- Student Research and Technology Committee, Bushehr University of Medical Sciences, Bushehr, Iran
3- Department of Obstetrics and Gynecology, School of Medicine, Bushehr University of Medical Sciences, Bu-shehr, Iran
4- Department of Microbiology & Parasitology, School of Medicine, Bushehr University of Medical Sciences, Bushehr, Iran ,mfouladvand35@gmail.com
2- Student Research and Technology Committee, Bushehr University of Medical Sciences, Bushehr, Iran
3- Department of Obstetrics and Gynecology, School of Medicine, Bushehr University of Medical Sciences, Bu-shehr, Iran
4- Department of Microbiology & Parasitology, School of Medicine, Bushehr University of Medical Sciences, Bushehr, Iran ,
Abstract: (762 Views)
Background: Congenital toxoplasmosis during early pregnancy may lead to fetal death or cause irreversible complications in the fetus. In the present research, the prevalence of anti-Toxoplasma IgG and IgM antibodies was determined in pregnant women with a history of spontaneous abortion in comparison with women of normal pregnancy course referring to Bushehr medical centers.
Materials and Methods: In this descriptive cross-sectional study, 150 blood samples were collected from pregnant women with a history of spontaneous abortion and normal pregnancy course referred to Bushehr medical centers from May 2020 to May 2021. Sera were tested for anti-Toxoplasma IgG and IgM antibodies using the ELISA method. The test results along with the questionnaire information were analyzed using SPSS-16 software and Chi-square test.
Results: A total of 18.7% were seropositive and 81.3% were seronegative for anti-Toxoplasma IgG/IgM antibodies. The comparison of the two groups of women showed that there was a significant relationship between the prevalence of anti-Toxoplasma IgG antibody and spontaneous abortion and also education level, place of residence and method of washing vegetables; however, there was no statistically significant relationship between infection and some of the analyzed variables, such as history of contact with cats, number of pregnancies, deliveries and abortions, and some nutritional behaviors.
Conclusion: Chronic form of toxoplasmosis can be considered a factor for recurrent miscarriage in pregnant women. Due to the emphasis of some researchers on the non-significance of this relationship, the subject is debatable and needs further studies.
Materials and Methods: In this descriptive cross-sectional study, 150 blood samples were collected from pregnant women with a history of spontaneous abortion and normal pregnancy course referred to Bushehr medical centers from May 2020 to May 2021. Sera were tested for anti-Toxoplasma IgG and IgM antibodies using the ELISA method. The test results along with the questionnaire information were analyzed using SPSS-16 software and Chi-square test.
Results: A total of 18.7% were seropositive and 81.3% were seronegative for anti-Toxoplasma IgG/IgM antibodies. The comparison of the two groups of women showed that there was a significant relationship between the prevalence of anti-Toxoplasma IgG antibody and spontaneous abortion and also education level, place of residence and method of washing vegetables; however, there was no statistically significant relationship between infection and some of the analyzed variables, such as history of contact with cats, number of pregnancies, deliveries and abortions, and some nutritional behaviors.
Conclusion: Chronic form of toxoplasmosis can be considered a factor for recurrent miscarriage in pregnant women. Due to the emphasis of some researchers on the non-significance of this relationship, the subject is debatable and needs further studies.
Type of Study: Original |
Subject:
Parasitology
Received: 2023/12/25 | Accepted: 2024/03/9 | Published: 2024/05/5
Received: 2023/12/25 | Accepted: 2024/03/9 | Published: 2024/05/5
References
1. Hatam GR, Shamseddin A, Nikouee F. Seroprevalence of toxoplasmosis in high school girls in Fasa district, Iran. Iran J Immunol 2005; 2(3): 177-181. [Article]
2. Jones J, Lopez A, Wilson M. Congenital toxoplasmosis. Am Fam Physician 2003; 67(10): 2131-2138. [PubMed]
3. Fouladvand M, Barazesh A, Naimei B, et al. Seroprevalence of toxoplasmosis in high school girls in Bushehr city, south west of Iran, 2009. Afr J Microbiol Res 2010; 4(11): 1117-1121. [DOI]
4. Al-Hamdani MM, Mahdi NK. Toxoplasmosis among women with habitual abortion. East Med Hlth J 1996; 3(2): 310-315. [Article]
5. Qublan HS, Jumaian N, Abu-Salem A, et al. Toxoplasmosis and habitual abortion. J Obstet Gynaecol 2002; 22(3): 296-8. [DOI]
6. Ndir I, Gaye A, Faye B, et al. Seroprevalence of Toxoplasmaosis among women having spontaneous abortion and pregnant women following in a center of health up-town in Dakar. Dakar Med 2004; 49(1): 5-9. [PubMed]
7. Hosseinzadeh M, Khosravi A, Kalantari B, et al. Seroepidemiological assessment of toxoplasmosis in women with and without abortion history in Ilam. Health Syst Res 2011; 6(4): 1- 9. (Persian) [Article]
8. Ebadi P, Solhjoo K, Bagheri K, et al. Seroprevalence of toxoplasmosis in women with recurrent spontaneous abortion in comparison with normal delivery. Pars J Med Sci 2011; 9(1): 1- 5. (Persian) [DOI]
9. Aali BSh, Fasihi Harandi M, Nazari E, et al. Comparison of Toxoplasma gondii IgG and IgM seropositivity between women with spontaneous abortions and ongoing pregnancies. Iran J Obstetric Gynecol Infertil 2011; 14(1): 1- 6. (Persian) [DOI]
10. Wen LZ, Liu LQ, Ao LM, et al. Effect of Toxoplasma infection during pregnancy to the development of fetus and infant. Zhonghua Fu Chan Ke Za Zhi 2003; 38(6): 331-333. [PubMed]
11. Singh N. Status of Toxoplasma antibodies in recurrent fetal loss in U.A.E. women. Indian J Pediatr 1998;65(6): 891-897. [DOI]
12. Sahwi SY, Zaki MS, Haiba NY, et al. Toxoplasmosis as a cause of repeated abortion. J Obstet Gynaecol 1995; 21(2): 145-148. [DOI]
13. Fouladvand M, Barazesh A, Naimei B, et al. Seroepidemiological study of toxoplasmosis in childbearing age women in Bushehr City, south west of Iran in 2009. Afr J Biotechnol 2010; 9(36): 5809-5812. [Article]
14. Motazedian MH, Fouladvand M, Barazesh A. The prevalence of toxoplasmosis in hemodialysis patients in Bushehr, Iran in 2012. J Mazandaran Univ Med Sci 2016; 26(141): 123-130. (Persian) [Article]
15. Saki J, Mohammadpour N, Moramezi F, et al. Seroprevalence of Toxoplasma gondii in women who have aborted in comparison with the women with normal delivery in Ahvaz, southwest of Iran. Scientific World J 2015; 2015: 764369. [DOI]
16. Nayeri T, Sarvi S, Moosazadeh M, et al. The global seroprevalence of anti-Toxoplasma gondii antibodies in women who had spontaneous abortion: A systematic review and metaanalysis. PLoS Negl Trop Dis 2020; 14(3): e0008103. [DOI]
17. Barazesh A, Sarkari B, Mehrabi Sisakht F, et al. Seroprevalence and molecular evaluation of toxoplasmosis in patients undergoing chemotherapy for malignancies in the Bushehr province, southwest Iran. Jundishapur J Microbiol 2016; 9(9): e35410. [DOI]
18. Fouladvand MA, Barazesh A, Naiemi B, et al. Seroepidemiological study of toxoplasmosis in girl students from Persian Gulf University and Bushehr University of Medical Sciences. Iran South Med J 2010; 13(2): 114-122. (Persian) [Article]
19. Âjami A, Sharif M, Saffar M, et al. Serological study of toxoplasmosis in women referred to medical health laboratory before marriage, Mazandaran, 2000. J Mazandaran Univ Med Sci 2001; 11(31): 51-56. (Persian) [Article]
20. Saeedi M, Bakhshandeh Nosrat S, Ghaemi E, et al. The prevalence of Toxoplasma antibodies in women during marriage consultation in Gorgan. J Gorgan Univ Med Sci 2002; 4(1): 64-70. (Persian) [Article]
21. Fallah E, Navazesh R, Majidi J, et al. An epidemiological study of Toxoplasma infection among high-school girls in Jolfa. J Reprod Infertil 2005; 6(3): 261-269. (Persian) [Article]
22. Daryani A, Sagha M, Sharif M, et al. Seroepidemiology of toxoplasmosis in women referred to Ardabil laboratory of health center for medical examinations before marriage, Iran, 2002. Int J Trop Med 2006; 1(1): 27-29. [Article]
23. Yang HJ, Jin KN, Park YK, et al. Seroprevalence of toxoplasmosis in the residents of Cheju Island, Korea. Korean J Parasitol 2000; 38(2): 91-93. [DOI]
24. Rafiei A, Hamadi A, Amani F. Seroprevalence of Toxoplasma among girl students in Ahvaz city, Iran. J Infect Trop Dis 2006; 10(31): 35-41. (Persian) [Article]
25. Ziaei Kajbaf T, Taheri M. Evaluation of prevalence of seropositively against toxoplasmosis among childbearing age women in Ahwaz city in year 2003. Jundishapur Scientific Med J 2008; 7(56): 92-99. (Persian) [Article]
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