Volume 27, Issue 2 (Iran South Med J 2024)                   Iran South Med J 2024, 27(2): 148-158 | Back to browse issues page


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Halvani A, Rafatmagham S, Poorteymori S. Relationship between Serum Sodium Level at Admission of Patients with Pulmonary Embo-lism and Their Prognosis during Hospitaliza-tion. Iran South Med J 2024; 27 (2) :148-158
URL: http://ismj.bpums.ac.ir/article-1-2013-en.html
1- Department of Internal Medicine, Yazd Medical Science Branch, Islamic Azad University, Yazd, Iran
2- Department of Internal Medicine, Fasa University of Medical Sciense, Fasa, Iran , R.sareh2012@gmail.com
3- Department of Medical Science Branch, Islamic Azad University, Yazd, Iran
Abstract:   (698 Views)
Background: The aim of this study was to assess the relationship between serum sodium level on admission and the prognosis of patients with pulmonary embolism.
Materials and Methods: The current descriptive-analytical study is cross-sectional, and 101 patients with pulmonary embolism who were admitted and treated in Shohadaye Kargar Hospital in Yazd in 2010-2020 were studied.
Results: The findings showed no difference between the mean serum sodium level at admission in patients with coronary disease, pulmonary disease, cancer and renal disease compared to other individuals. The mean serum sodium level on admission of patients who were hospitalized in the ICU was lower than the non-ICU admissions. No significant relationship was observed between serum sodium level and the length of hospitalization. There was a significant relationship between the need for ICU admission and serum sodium level, and ICU admission was more common in patients with hyponatremia. There was no significant relationship between ICU admission and the patients' age, treatment outcomes, and right ventricular dysfunction. There was also no significant relationship between the patients’ age, right ventricular dysfunction and serum sodium levels and treatment outcomes.
Conclusion: Hyponatraemia on admission predicts poor outcome and is an independent risk factor for ICU admission in patients with pulmonary embolism. As a result, this issue requires careful consideration and further study.
Full-Text [PDF 586 kb]   (248 Downloads)    
Type of Study: Original | Subject: Lung diseases
Received: 2024/08/26 | Accepted: 2024/10/19 | Published: 2024/12/7

References
1. Nasirian M, Gharepapagh E, Fakhari A, et al. Evaluation of D-dimer Test Correlation with Lung Perfusion-Ventilation Scan in Patients Suspected Pulmonary Embolism. Iran South Med J 2023; 25(6): 519-530. (Persian) [Article]
2. Pforte A. Epidemiology, diagnosis and thrapy of pulmonary embolism. Eur J Med Res 2004; 9(4): 171-9. [Article]
3. Yousefi Abdolmaleki E, Teymourzadeh Baboli M, Abedi Samakoosh M, et al. Hyponatremia and Dependent Factors in Admitted Patients with Tuberculosis at Razi Teaching Hospital, North of Iran 2006- 2011. J Mazandaran Univ Med Sci 2013; 22(97): 12-16. (Persian) [Article]
4. Park B, Messina L, Dargon P, et al. Recent trends in clinical outcomes and resource utilization for pulmonary embolism in the United States: findings from the nationwide inpatient sample. Chest 2009; 136(4): 983-90. [DOI]
5. Zhou XY, Chen HL, Ni SS. Hyponatremia and shortterm prognosis of patients with acute pulmonary embolism: A meta-analysis. Int J Cardiol 2017; 227: 251-6. [DOI]
6. Rahimtoola A, Bergin J. Acute pulmonary embolism: an update on diagnosis and management. Current problems in cardiology 2015; 30(2): 61-114. [DOI]
7. Kumar V, Abbas A, Fausto N, et al. Basic Pathology. Saunders, 2012, 98. [Article]
8. Goldhaber S, Kasper D, Braunwald E & et al. Harrison's Principles of Internal Medicine. 19th ed. New York, NY 2015; (300): 1561-5. [Article]
9. Lewis Sh L, Dirksen Sh R, Heitkemper M M & et al. Medical - surgical nursing: Assessment and management of clinical problems. 9 ed, Mosby, 2013, 552. [Article]
10. Gharehpapagh E, Salarifard A. Clinical examination of pulmonary embolism by scanperfusion radiopharmaceuticals and lung ventilation. Med J Tabriz Uni Med Sciences 2011; 33(5): 71-77. [Article]
11. Schers N. Prognostic Importance of Hyponatremia in Patients with Acute Pulmonary Embolism. Am J Respir Crit Care Med 2010; 182(9): 1178-83. [DOI]
12. Karimian J, Entezari M, Pahlavani N & et al. Evaluation the effects of L-arginine supplementation on exercise performance, body composition and serum sodium and potassium in healthy male athletes. Iran South Med J 2016; 18(6): 1186-97. [Article]
13. Nasirian M, Gharepapagh E, Fakhari A & et al. Evaluation of D-dimer Test Correlation with Lung PerfusionVentilation Scan in Patients Suspected Pulmonary Embolism. Iran South Med J 2023; 25(6): 519-530. [Article]
14. Müller M, Schefold J C, Guignard V & et al. Hyponatraemia is independently associated with in-hospital mortality in patients with pneumonia. Eur J Intern Med 2018; 54: 46-52. [DOI]
15. Winther JA, Brynildsen J, Høiseth AD & et al. Prevalence and Prognostic Significance of Hyponatremia in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease: Data from the Akershus Cardiac Examination (ACE) 2 Study. PLOS ONE 2016; 11(8): 1-14. [Article]
16. Chalela R, González-García J, Chillarón J & et al. Impact of hyponatremia on mortality and morbidity in patients with COPD exacerbations. Respiratory Medicine 2016; 117: 237-42. [DOI]
17. Jaff MR, McMurtry MS, Archer SL & et al. Management of massive and submassive pulmonary embolism, Iliofemoral Deep Vein Thrombosis, and Chronic Thromboembolic Pulmonary Hypertension: A Scientific Statement From the American Heart Association. Circulation 2011; 123(16): 1788-830. [DOI]
18. Zilberberg MD, Exuzides A, Spalding J & et al. Hyponatremia and hospital outcomes among patients with pneumonia: a retrospective cohort study. BMC Pulm Med 2008; 8(16). [DOI]
19. Forfia PR, Mathai SC, Fisher MR & et al. Hyponatremia predicts right heart failure and poor survival in pulmonary arterial hypertention. Am J Respir Crit Care Med 2008; 177(12): 1364-9. [DOI]
20. Cho JH, Sridharan GK, Kim SH & et al. Right ventricular dysfunction as an echocardiographic prognostic factor in hemodynamically stable patients with acute pulmonary embolism: a meta-analysis. BMC Cardiovasc Disord 2014; 14: 64. [DOI]

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