ISMJ

Abstract Background: Imipenem is a betalactam antibioticthat has antibacterial activity against gram positive,gram negative and anerobic species. Antibiotic resistance is a problem in Iran. In this study, we asses imipenem resistance in blood cultures in Bushehr educational hospitals. Material and method:This cross sectional study was done in 2010. Blood cultures were taken from admitted patients in hospitals. For all samples, antibiogram with disk diffusion was done. And result of culture was categorized into three groups :resistance, sensitive and intermediate. Data was analyzed with SPSS Version13. Results: This study consisted of 200 patients. 48% Male, 37% female, 14% NeonateThe age of study group was ranged between 1 and 90 years (Mean 21, Standard deviation 28). . Psuedomonus aeroginosa and staphilococcus epidermis had higher perevalence. Resistancy to imipenem was 29/5%. Resistancy to imipenem was 41/4% in NICU. Concdlsion: Findings indicated that antibiotic resistancy is increasing in Bushehr. Therfore, it is necessary to modify antibiotic prescription and restrict using wide spectrum antibiotics such as imipenem.