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:: Volume 18, Number 6 (Iranian South Medical Journal 2016) ::
Iran South Med J 2016, 18(6): 1179-1185 Back to browse issues page
The effects of Hyperglycemia and Hyperlipidemia on blood indices
Mohammad Mahmoudi1, Shaban Alizadeh2, Akbar Dorgalaleh2, Shadi Tabibian3, Samira Esmaeili Reykandeh3, Morteza Shamsizadeh *4
1- Minoodasht Pathobiological Laboratory, Minnodasht, Golestan, Iran
2- Department of Hematology and Transfusion Medicine, School of Allied Medical Sciences, Tehran University of Medical Sciences, Tehran, Iran
3- Department of Hematology and Transfusion Medicine, School of Allied Medical Sciences, Tehran University of Medical Sciences, Tehran, Iran Allied Medical Student's Scientific Research Center, Tehran University of Medical Sciences, Tehran, Iran
4- Faculty Member, School of Nursing and Midwifery, Shahroud University of Medical Sciences, Shahroud, Iran , shamsizadeh@shmu.ac.ir
Abstract:   (1234 Views)

Background: Cell Blood Count (CBC) are performed with automatic analysers in laboratories.It works based on three principles electrical impedance, scatter light and flowcytometry. Many factors might affect results by these machines. This study was performed to assay the effect of some confounders on the results of analysers that work based on electrical resistance.

Material and method: This analytical study (case- control) was conducted on 243 persons with hyperglycemia and hyperlipidemia and 100 healthy persosn (control group) in Fateme Zahra Hospital in North of Iran, Golestan. First, Blood glucose and triglyceride were measured with biochemical analyser and CBC was performed for each person. Finally, Statistical analysis and comparison between two groups were performed with SPSS software.

Resuts: Comparison between case and control group was shown that both hyperlipidemia and hyperglycemia cause increase in  Mean Cell Volume (MCV) and also hyperlipidemia can cause increase in Mean Cell Hemoglobin Concentration (MCHC), Hemoglobin and Hematocrit (Hct) with (P<0.05)

Conclusion: According to this study, confounding factors such as hyperglycemia and hyperlipidemia can affect the results of analysers that work based on electrical impedance and it should be considered in laboratories.

Keywords: hyperlipidemia, hyperglycemia, automatic analyser, Hematologic indices
Full-Text [PDF 425 kb]   (577 Downloads)    
Type of Study: Original | Subject: Hemic and Lymphatic Systems
Received: 2015/12/22 | Accepted: 2015/12/22 | Published: 2015/12/22
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DOI: 10.7508/ismj.1394.06.008
PMCID: 27496582


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Mahmoudi M, Alizadeh S, Dorgalaleh A, Tabibian S, Esmaeili Reykandeh S, Shamsizadeh M. The effects of Hyperglycemia and Hyperlipidemia on blood indices. Iran South Med J. 2016; 18 (6) :1179-1185
URL: http://ismj.bpums.ac.ir/article-1-751-en.html
Volume 18, Number 6 (Iranian South Medical Journal 2016) Back to browse issues page
دانشگاه علوم پزشکی بوشهر، طب جنوب ISMJ

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